Joan W. Conaway

Stowers Institute for Medical Research

Affiliated withStowers Institute for Medical Research Kansas University Medical Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 8	2014
Publication title Cited by 4	2014
Publication title Cited by 1	2019

Other Publications

Article	Year
Roles of SCF and VHL ubiquitin ligases in regulation of cell growth. Progress in molecular and subcellular biology\| PubMed ID: 11908068	2002
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature\| PubMed ID: 11961546	2002
A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase. The Journal of biological chemistry\| PubMed ID: 12048197	2002
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12351678	2002
The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription. Advances in cancer research\| PubMed ID: 12374282	2002
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. The Journal of biological chemistry\| PubMed ID: 12538644	2003
von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12604794	2003
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular cell\| PubMed ID: 15175151	2004
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex. The Journal of biological chemistry\| PubMed ID: 15590664	2005
Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. The Journal of biological chemistry\| PubMed ID: 15611125	2005
The mammalian Mediator complex and its role in transcriptional regulation. Trends in biochemical sciences\| PubMed ID: 15896743	2005
Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes. Methods (San Diego, Calif.)\| PubMed ID: 17101442	2006
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors. The EMBO journal\| PubMed ID: 17110932	2006
Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. The Journal of biological chemistry\| PubMed ID: 17150956	2007
RNA polymerase II: a "nobel" enzyme demystified. Molecular cell\| PubMed ID: 17157247	2006
YY1 functions with INO80 to activate transcription. Nature structural & molecular biology\| PubMed ID: 17721549	2007
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. The Journal of biological chemistry\| PubMed ID: 18077452	2008
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. The Journal of biological chemistry\| PubMed ID: 18187417	2008
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18218781	2008
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Molecular cell\| PubMed ID: 18922472	2008
Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1. The EMBO journal\| PubMed ID: 19037258	2008
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. The Journal of biological chemistry\| PubMed ID: 19049968	2009
Direct inhibition of RNA polymerase II transcription by RECQL5. The Journal of biological chemistry\| PubMed ID: 19570979	2009
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19666485	2009
Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID. The Journal of biological chemistry\| PubMed ID: 19805548	2009
Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19920177	2009
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. The Journal of biological chemistry\| PubMed ID: 20018852	2010
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular cell\| PubMed ID: 20159561	2010
When transcription meets recombination: a lesson from the human RECQ protein complexes. F1000 biology reports\| PubMed ID: 20948612	2009
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell\| PubMed ID: 21295698	2011
Thematic minireview series on computational systems biology. The Journal of biological chemistry\| PubMed ID: 21566145	2011
Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell\| PubMed ID: 21729782	2011
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. The EMBO journal\| PubMed ID: 21822215	2011
Introduction to theme "Chromatin, epigenetics, and transcription". Annual review of biochemistry\| PubMed ID: 22404631	2012
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. PloS one\| PubMed ID: 22912744	2012
Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation. Cell reports\| PubMed ID: 23122963	2012
Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate. The Journal of biological chemistry\| PubMed ID: 23132853	2012
Immunoaffinity purification of protein complexes from Mammalian cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23436370	2013
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction. Nature structural & molecular biology\| PubMed ID: 23563140	2013
Transcriptional properties of mammalian elongin A and its role in stress response. The Journal of biological chemistry\| PubMed ID: 23828199	2013
Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes. PLoS genetics\| PubMed ID: 24244196	2013
Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24297934	2013
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex. Cell\| PubMed ID: 24882805	2014