Sylvie Claeysen

CNRS, Institut de Génomique Fonctionnelle, Montpellier

Affiliated withInstitut de Génomique Fonctionnelle, Montpellier U661, Montpellier Universités de Montpellier

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 65	2014
Publication title Cited by 9	2016

Other Publications

Article	Year
G protein-coupled receptors: dominant players in cell-cell communication. International review of cytology\| PubMed ID: 11804040	2002
A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists. The Journal of biological chemistry\| PubMed ID: 11976337	2002
A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist. FEBS letters\| PubMed ID: 12062436	2002
A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL). The Journal of biological chemistry\| PubMed ID: 12441358	2003
New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. Journal of cell science\| PubMed ID: 15466885	2004
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor. The Journal of biological chemistry\| PubMed ID: 15722344	2005
Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2. FEBS letters\| PubMed ID: 15811337	2005
Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements. The Journal of biological chemistry\| PubMed ID: 15919661	2005
Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation. Cell and tissue research\| PubMed ID: 16896947	2006
5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling. Molecular biology of the cell\| PubMed ID: 17377064	2007
Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor. PloS one\| PubMed ID: 18338032	2007
5-HT(4) receptors: history, molecular pharmacology and brain functions. Neuropharmacology\| PubMed ID: 18603269	2008
Engineering GPCR signaling pathways with RASSLs. Nature methods\| PubMed ID: 18668035	2008
Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors. Molecular pharmacology\| PubMed ID: 19168624	2009
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. The EMBO journal\| PubMed ID: 19661922	2009
Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation. Journal of medicinal chemistry\| PubMed ID: 20078106	2010
G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient. The Journal of biological chemistry\| PubMed ID: 21247891	2011
5-HT(4) receptors, a place in the sun: act two. Current opinion in pharmacology\| PubMed ID: 21342787	2011
Alzheimer culprits: cellular crossroads and interplay. Cellular signalling\| PubMed ID: 22627093	2012
Pharmacological profile of engineered 5-HT₄ receptors and identification of 5-HT₄ receptor-biased ligands. Brain research\| PubMed ID: 23148949	2013
5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10. ACS chemical neuroscience\| PubMed ID: 23336052	2013
Serotonin type 4 receptor dimers. Methods in cell biology\| PubMed ID: 24143975	2013
Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease. Frontiers in aging neuroscience\| PubMed ID: 24399967	2013
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25157130	2014
Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's... Journal of medicinal chemistry\| PubMed ID: 25793650	2015
Serotonin: A New Hope in Alzheimer's Disease? ACS chemical neuroscience\| PubMed ID: 26011650	2015
Cerebrovascular pathology during the progression of experimental Alzheimer's disease. Neurobiology of disease\| PubMed ID: 26774030	2016