This manuscript describes a procedure to track the remodeling of the cerebrovasculature during amyloid plaque accumulation in vivo using longitudinal two-photon microscopy. A thinned-skull preparation enables the visualization of fluorescent dyes to assess the progression of cerebrovascular damage in a mouse model of Alzheimer's disease.

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

•

•

•

Chapters

Summary

Automatic Translation

Tags

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System

Intranasal Administration of CNS Therapeutics to Awake Mice

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Transplantation into the Anterior Chamber of the Eye for Longitudinal, Non-invasive In vivo Imaging with Single-cell Resolution in Real-time

In vivo ¹⁹F MRI for Cell Tracking

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging

Rose Bengal Photothrombosis by Confocal Optical Imaging In Vivo: A Model of Single Vessel Stroke

Depletion of Mouse Cells from Human Tumor Xenografts Significantly Improves Downstream Analysis of Target Cells

Read Article