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JoVE Journal
Neuroscience

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Primary Culture of Mouse Dopaminergic Neurons
 

Primary Culture of Mouse Dopaminergic Neurons

Article DOI: 10.3791/51751
September 8th, 2014

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Summary September 8th, 2014

Dopaminergic neurons play a vital regulatory role in the brain. Their loss is associated with Parkinson's disease. In this video, we show how to generate primary cultures of central dopaminergic neurons from embryonic mouse mesencephalon. Such cultures are useful to study the extreme vulnerability of these neurons to various stresses.

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