Frank Tacke

Department of Medicine III, RWTH Aachen University

Affiliated withRWTH Aachen University RWTH University-Hospital Aachen

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 300	2015
Publication title Cited by 27	2015

Other Publications

Article	Year
TNFα-mediated liver destruction by Kupffer cells and Ly6Chi monocytes during Entamoeba histolytica infection. PLoS pathogens\| PubMed ID: 23300453	2013
Serum concentrations of A Proliferation-Inducing Ligand (APRIL) are elevated in sepsis and predict mortality in critically ill patients. Journal of critical care\| PubMed ID: 23337484	2013
Circulating microRNA-150 serum levels predict survival in patients with critical illness and sepsis. PloS one\| PubMed ID: 23372743	2013
Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis. Biochimica et biophysica acta\| PubMed ID: 23376114	2013
Elastin-based molecular MRI of liver fibrosis. Hepatology (Baltimore, Md.)\| PubMed ID: 23424008	2013
From NAFLD to NASH to fibrosis to HCC: role of dendritic cell populations in the liver. Hepatology (Baltimore, Md.)\| PubMed ID: 23519833	2013
Serum sodium based modification of the MELD does not improve prediction of outcome in acute liver failure. BMC gastroenterology\| PubMed ID: 23551795	2013
Met-CCL5 modifies monocyte subpopulations during liver fibrosis regression. International journal of clinical and experimental pathology\| PubMed ID: 23573314	2013
Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23596313	2013
Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis. Biochimica et biophysica acta\| PubMed ID: 23770341	2013
Frequency and phenotype of human circulating and intrahepatic natural killer cell subsets is differentially regulated according to stage of chronic liver disease. Digestion\| PubMed ID: 23774822	2013
YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23872051	2013
Regulation and prognostic relevance of symmetric dimethylarginine serum concentrations in critical illness and sepsis. Mediators of inflammation\| PubMed ID: 23935249	2013
Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients. Journal of critical care\| PubMed ID: 23953490	2013
Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis. Hepatology (Baltimore, Md.)\| PubMed ID: 23959575	2014
RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation. Cell reports\| PubMed ID: 23972991	2013
U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis. Experimental & molecular medicine\| PubMed ID: 24052167	2013
HBV Subgenotypes D1, D2, D-del! Are 'Old' Genotyping Methods Interpreted Correctly? Hepatitis monthly\| PubMed ID: 24066000	2013
Experimental liver fibrosis research: update on animal models, legal issues and translational aspects. Fibrogenesis & tissue repair\| PubMed ID: 24274743	2013
Macrophage heterogeneity in liver injury and fibrosis. Journal of hepatology\| PubMed ID: 24412603	2014
Levels of circulating miR-133a are elevated in sepsis and predict mortality in critically ill patients. Critical care medicine\| PubMed ID: 24413579	2014
High prevalence of Y-box protein-1/p18 fragment in plasma of patients with malignancies of different origin. BMC cancer\| PubMed ID: 24443788	2014
Pharmacological inhibition of the chemokine C-C motif chemokine ligand 2 (monocyte chemoattractant protein 1) accelerates liver fibrosis regression by suppressing Ly-6C(+) macrophage infiltr... Hepatology (Baltimore, Md.)\| PubMed ID: 24481979	2014
Role of lymphocytes in liver cancer. Oncoimmunology\| PubMed ID: 24498546	2013
CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis. Gut\| PubMed ID: 24561613	2014
Eat more carrots? Dampening cell death in ethanol-induced liver fibrosis by β-carotene. Hepatobiliary surgery and nutrition\| PubMed ID: 24570954	2013
Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 24575897	2014
Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 24607939	2014
Administration of proton pump inhibitors in critically ill medical patients is associated with increased risk of developing Clostridium difficile-associated diarrhea. Journal of critical care\| PubMed ID: 24674763	2014
Translation control of TAK1 mRNA by hnRNP K modulates LPS-induced macrophage activation. RNA (New York, N.Y.)\| PubMed ID: 24751651	2014
Role of gamma-delta T cells in liver inflammation and fibrosis. World journal of gastrointestinal pathophysiology\| PubMed ID: 24891982	2014
GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering. Diabetes\| PubMed ID: 24947356	2014
A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis. EMBO molecular medicine\| PubMed ID: 24963148	2014
Molecular identification of hepatitis B virus genotypes/subgenotypes: revised classification hurdles and updated resolutions. World journal of gastroenterology : WJG\| PubMed ID: 24966586	2014
Elevated miR-122 serum levels are an independent marker of liver injury in inflammatory diseases. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 25039534	2014
Roles for chemokines in liver disease. Gastroenterology\| PubMed ID: 25066692	2014
Interleukins in chronic liver disease: lessons learned from experimental mouse models. Clinical and experimental gastroenterology\| PubMed ID: 25214799	2014
Distinct patterns of IgG and IgA against food and microbial antigens in serum and feces of patients with inflammatory bowel diseases. PloS one\| PubMed ID: 25215528	2014
Cyclic adenosine monophosphate-responsive element modulator alpha overexpression impairs function of hepatic myeloid-derived suppressor cells and aggravates immune-mediated hepatitis in mice... Hepatology (Baltimore, Md.)\| PubMed ID: 25330465	2014
Pharmacological inhibition of the chemokine CXCL16 diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury. PloS one\| PubMed ID: 25372401	2014
Variceal bleeding in liver cirrhosis at the ICU: sufficient data to treat adrenal insufficiency?*. Critical care medicine\| PubMed ID: 25402288	2014
Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases. Biomaterials\| PubMed ID: 25453965	2015
CXCL9 is a prognostic marker in patients with liver cirrhosis receiving transjugular intrahepatic portosystemic shunt. Journal of hepatology\| PubMed ID: 25457205	2015
Reply: To PMID 24481979. Gastroenterology\| PubMed ID: 25457849	2014
Liver immunology: new perspectives. Hepatobiliary surgery and nutrition\| PubMed ID: 25568857	2014
Immune mechanisms in acetaminophen-induced acute liver failure. Hepatobiliary surgery and nutrition\| PubMed ID: 25568858	2014
Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology. Hepatobiliary surgery and nutrition\| PubMed ID: 25568859	2014
Therapeutic targeting of liver inflammation and fibrosis by nanomedicine. Hepatobiliary surgery and nutrition\| PubMed ID: 25568860	2014