Francesca Granucci

Department of Biotechnology and Biosciences, University of Milano-Bicocca

Affiliated withUniversity of Milano-Bicocca Humanitas Clinical and Research Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 21	2016
Publication title Cited by 9	2018

Other Publications

Article	Year
IL-2 mediates adjuvant effect of dendritic cells. Trends in immunology\| PubMed ID: 11923103	2002
Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12193691	2002
Toll-like receptor 4 is not required for the full maturation of dendritic cells or for the degradation of Gram-negative bacteria. European journal of immunology\| PubMed ID: 12355432	2002
Opinion: Interpretation of the complexity of innate immune responses by functional genomics. Nature reviews. Immunology\| PubMed ID: 12415311	2002
Interactions of bacterial pathogens with dendritic cells during invasion of mucosal surfaces. Current opinion in microbiology\| PubMed ID: 12615223	2003
Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12734352	2003
Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity. The EMBO journal\| PubMed ID: 12773371	2003
The immune response is initiated by dendritic cells via interaction with microorganisms and interleukin-2 production. The Journal of infectious diseases\| PubMed ID: 12792850	2003
The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia. Blood\| PubMed ID: 12842997	2003
A type I IFN-dependent pathway induced by Schistosoma mansoni eggs in mouse myeloid dendritic cells generates an inflammatory signature. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14978105	2004
The regulatory role of dendritic cells in the immune response. International archives of allergy and immunology\| PubMed ID: 15178886	2004
A contribution of mouse dendritic cell-derived IL-2 for NK cell activation. The Journal of experimental medicine\| PubMed ID: 15289500	2004
The European dimension for the mouse genome mutagenesis program. Nature genetics\| PubMed ID: 15340424	2004
Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice. Blood\| PubMed ID: 15353479	2005
A central role for tissue-resident dendritic cells in innate responses. Trends in immunology\| PubMed ID: 15530834	2004
A power law global error model for the identification of differentially expressed genes in microarray data. BMC bioinformatics\| PubMed ID: 15606915	2004
A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana. European journal of immunology\| PubMed ID: 15657947	2005
Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15944286	2005
TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15972660	2005
Synthesis and biological evaluation of novel lipid A antagonists. Bioorganic & medicinal chemistry\| PubMed ID: 16203155	2006
Dendritic cell biology. Advances in immunology\| PubMed ID: 16227091	2005
Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16547236	2006
Induction of peripheral T cell tolerance by antigen-presenting B cells. II. Chronic antigen presentation overrules antigen-presenting B cell activation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16547237	2006
Dendritic cells in pathogen recognition and induction of immune responses: a functional genomics approach. Journal of leukocyte biology\| PubMed ID: 16641136	2006
Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis. European journal of immunology\| PubMed ID: 16708398	2006
Natural killer (NK) cell functions can be strongly boosted by activated dendritic cells (DC). European journal of immunology\| PubMed ID: 17013979	2006
Inhibition of lipid a stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides. Angewandte Chemie (International ed. in English)\| PubMed ID: 17387663	2007
Self-tolerance, dendritic cell (DC)-mediated activation and tissue distribution of natural killer (NK) cells. Immunology letters\| PubMed ID: 17451813	2007
Gene expression profiling of dendritic cells by microarray. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 17876096	2007
Central role of dendritic cells in the regulation and deregulation of immune responses. Cellular and molecular life sciences : CMLS\| PubMed ID: 18327662	2008
Image filtering for two-photon deep imaging of lymphonodes. European biophysics journal : EBJ\| PubMed ID: 18389230	2008
Role of Toll like receptor-activated dendritic cells in the development of autoimmunity. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 18508547	2008
Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice. Glia\| PubMed ID: 18615568	2008
Generation of murine growth factor-dependent long-term dendritic cell lines to investigate host-parasite interactions. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19347308	2009
CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation. Nature\| PubMed ID: 19525933	2009
The dendritic cell life cycle. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19887908	2009
Straightforward synthesis of novel Akt inhibitors based on a glucose scaffold. Carbohydrate research\| PubMed ID: 20044079	2010
Gene expression profiles identify inflammatory signatures in dendritic cells. PloS one\| PubMed ID: 20195376	2010
Regulation of antigen uptake, migration, and lifespan of dendritic cell by Toll-like receptors. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 20556351	2010
Differences in lipopolysaccharide-induced signaling between conventional dendritic cells and macrophages. Immunobiology\| PubMed ID: 20579765	2010
The regulatory role of dendritic cells in the induction and maintenance of T-cell tolerance. Autoimmunity\| PubMed ID: 20670116	2011
Deciphering the complexity of Toll-like receptor signaling. Cellular and molecular life sciences : CMLS\| PubMed ID: 20680392	2010
A dairy bacterium displays in vitro probiotic properties for the pharyngeal mucosa by antagonizing group A streptococci and modulating the immune response. Infection and immunity\| PubMed ID: 20732995	2010
Accumulative difference image protocol for particle tracking in fluorescence microscopy tested in mouse lymphonodes. PloS one\| PubMed ID: 20808918	2010
DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells. Immunome research\| PubMed ID: 21092113	2010
Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling. Angewandte Chemie (International ed. in English)\| PubMed ID: 21226138	2011
Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants. European journal of immunology\| PubMed ID: 21688262	2011
CD14 controls the LPS-induced endocytosis of Toll-like receptor 4. Cell\| PubMed ID: 22078883	2011
Similarities and differences of innate immune responses elicited by smooth and rough LPS. Immunology letters\| PubMed ID: 22207037	2012
CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice. The Journal of clinical investigation\| PubMed ID: 22466648	2012
Regulation and dysregulation of innate immunity by NFAT signaling downstream of pattern recognition receptors (PRRs). European journal of immunology\| PubMed ID: 22706795	2012
Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells. Blood\| PubMed ID: 22760781	2012
The timing of IFNÎ² production affects early innate responses to Listeria monocytogenes and determines the overall outcome of lethal infection. PloS one\| PubMed ID: 22912878	2012
EFIS-EJI Ita Askonas Award. Q&A with Francesca Granucci, winner of the EFIS-EJI Ita Askonas Award 2012. European journal of immunology\| PubMed ID: 23108931	2012
The nature of activatory and tolerogenic dendritic cell-derived signal 2. Frontiers in immunology\| PubMed ID: 23882267	2013
Migratory conventional dendritic cells in the induction of peripheral T cell tolerance. Journal of leukocyte biology\| PubMed ID: 23898045	2013
Role of CD14 in host protection against infections and in metabolism regulation. Frontiers in cellular and infection microbiology\| PubMed ID: 23898465	2013
Systemically administered DNA and fowlpox recombinants expressing four vaccinia virus genes although immunogenic do not protect mice against the highly pathogenic IHD-J vaccinia strain. Virus research\| PubMed ID: 24050999	2013
IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions. Cell reports\| PubMed ID: 24055061	2013
Modeling leukocyte-leukocyte non-contact interactions in a lymph node. PloS one\| PubMed ID: 24204669	2013
Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity. European journal of immunology\| PubMed ID: 24338698	2014
Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic. Chembiochem : a European journal of chemical biology\| PubMed ID: 24339336	2014
The nature of activatory and tolerogenic dendritic cell-derived signal 2. Frontiers in immunology\| PubMed ID: 24567734	2014
rBet v 1 immunotherapy of sensitized mice with Streptococcus thermophilus as vehicle and adjuvant. Human vaccines & immunotherapeutics\| PubMed ID: 24603094	2014
Murein lytic enzyme TgaA of Bifidobacterium bifidum MIMBb75 modulates dendritic cell maturation through its cysteine- and histidine-dependent amidohydrolase/peptidase (CHAP) amidase domain. Applied and environmental microbiology\| PubMed ID: 24814791	2014
Microbe- and danger-induced inflammation. Molecular immunology\| PubMed ID: 25037632	2015
"Endotoxin, TLR4 signaling and beyond". Molecular immunology\| PubMed ID: 25218433	2015
Cream formulation impact on topical administration of engineered colloidal nanoparticles. PloS one\| PubMed ID: 25962161	2015
A role for CCR5(+)CD4 T cells in cutaneous psoriasis and for CD103(+) CCR4(+) CD8 Teff cells in the associated systemic inflammation. Journal of autoimmunity\| PubMed ID: 27068801	2016
Prolonged contact with dendritic cells turns lymph node-resident NK cells into anti-tumor effectors. EMBO molecular medicine\| PubMed ID: 27406819	2016
Blood to skin recirculation of CD4 memory T cells associates with cutaneous and systemic manifestations of psoriatic disease. Clinical immunology (Orlando, Fla.)\| PubMed ID: 28392462	2017
Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood. Scientific reports\| PubMed ID: 28798369	2017
IFN-λ suppresses intestinal inflammation by non-translational regulation of neutrophil function. Nature immunology\| PubMed ID: 28846084	2017
Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases. Seminars in immunology\| PubMed ID: 28855088	2017
Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems. Science immunology\| PubMed ID: 28939652	2017
Nanoparticles: "magic bullets" for targeting the immune system. Seminars in immunology\| PubMed ID: 29173493	2017
Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs. Frontiers in immunology\| PubMed ID: 29234323	2017
The Family of LPS Signal Transducers Increases: the Arrival of Chanzymes. Immunity\| PubMed ID: 29343439	2018
Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation. Cell death & disease\| PubMed ID: 29449625	2018