Stephen J. Galli

Department of Pathology, Stanford University School of Medicine

Affiliated withStanford University School of Medicine Stanford University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 21	2015
Publication title Cited by 10	2018

Other Publications

Article	Year
In vivo immunological function of mast cells derived from embryonic stem cells: an approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 10908668	2000
Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. The Journal of experimental medicine\| PubMed ID: 10934234	2000
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nature medicine\| PubMed ID: 11984595	2002
Mast cells derived from embryonic stem cells: a model system for studying the effects of genetic manipulations on mast cell development, phenotype, and function in vitro and in vivo. International journal of hematology\| PubMed ID: 12041662	2002
Analyzing the roles of mast cells and basophils in host defense and other biological responses. International journal of hematology\| PubMed ID: 12041665	2002
Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11. BMC immunology\| PubMed ID: 12079505	2002
Probing the roles of mast cells and basophils in natural and acquired immunity, physiology and disease. Trends in immunology\| PubMed ID: 12200056	2002
Regulation of mast-cell and basophil function and survival by IgE. Nature reviews. Immunology\| PubMed ID: 12360215	2002
Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12576552	2003
Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus. BMC immunology\| PubMed ID: 12597780	2003
Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12817015	2003
Involvement of both 'allergic' and 'autoimmune' mechanisms in EAE, MS and other autoimmune diseases. Trends in immunology\| PubMed ID: 12967671	2003
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14569021	2003
Mast cells to the defense. Nature immunology\| PubMed ID: 14639463	2003
Chair's introduction. Anaphylaxis. Novartis Foundation symposium\| PubMed ID: 15025388	2004
Immune sensitization in the skin is enhanced by antigen-independent effects of IgE. Immunity\| PubMed ID: 15084268	2004
RabGEF1 is a negative regulator of mast cell activation and skin inflammation. Nature immunology\| PubMed ID: 15235600	2004
Lack of significant skin inflammation during elimination by apoptosis of large numbers of mouse cutaneous mast cells after cessation of treatment with stem cell factor. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 15502858	2004
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. Nature\| PubMed ID: 15543132	2004
Mast cells in the development of adaptive immune responses. Nature immunology\| PubMed ID: 15662442	2005
Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumors. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 15696191	2005
Pathogenesis and management of anaphylaxis: current status and future challenges. The Journal of allergy and clinical immunology\| PubMed ID: 15753906	2005
Symposium on the definition and management of anaphylaxis: summary report. The Journal of allergy and clinical immunology\| PubMed ID: 15753908	2005
Mast cells as "tunable" effector and immunoregulatory cells: recent advances. Annual review of immunology\| PubMed ID: 15771585	2005
Nipping cat allergy with fusion proteins. Nature medicine\| PubMed ID: 15812517	2005
Mast cells enhance T cell activation: Importance of mast cell-derived TNF. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15840716	2005
Adoptive transfer of mast cells does not enhance the impaired survival of Kit(W)/Kit(W-v) mice in a model of low dose intraperitoneal infection with bioluminescent Salmonella typhimurium. Immunology letters\| PubMed ID: 15894120	2005
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. Blood\| PubMed ID: 15972446	2005
Identification of mast cell progenitors in adult mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16006518	2005
Using mast cell knock-in mice to analyze the roles of mast cells in allergic responses in vivo. Chemical immunology and allergy\| PubMed ID: 16107772	2005
Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo. The American journal of pathology\| PubMed ID: 16127161	2005
Monomeric IgE enhances human mast cell chemokine production: IL-4 augments and dexamethasone suppresses the response. The Journal of allergy and clinical immunology\| PubMed ID: 16337471	2005
A key regulatory role for histamine in experimental autoimmune encephalomyelitis: disease exacerbation in histidine decarboxylase-deficient mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16365391	2006
Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNF. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16455980	2006
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. The Journal of allergy and clinical immunology\| PubMed ID: 16461139	2006
RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16533754	2006
Second symposium on the definition and management of anaphylaxis: summary report--second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. Annals of emergency medicine\| PubMed ID: 16546624	2006
Mast cell-associated TNF promotes dendritic cell migration. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16547246	2006
Interleukin-4-triggered, STAT6-dependent production of a factor that induces mouse mast cell apoptosis. European journal of immunology\| PubMed ID: 16598817	2006
Immune sensitization in the skin is enhanced by antigen-independent effects of IgE on mast cells. Novartis Foundation symposium\| PubMed ID: 16605126	2005
RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation. Novartis Foundation symposium\| PubMed ID: 16605131	2005
Mast cells can promote the development of multiple features of chronic asthma in mice. The Journal of clinical investigation\| PubMed ID: 16710480	2006
Mast cells can enhance resistance to snake and honeybee venoms. Science (New York, N.Y.)\| PubMed ID: 16873664	2006
Interleukin-3 and c-Kit/stem cell factor are required for normal eosinophil responses in mice infected with Strongyloides venezuelensis. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 16894356	2006
Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses. Current opinion in immunology\| PubMed ID: 17011762	2006
Mast cell-derived tumor necrosis factor can promote nerve fiber elongation in the skin during contact hypersensitivity in mice. The American journal of pathology\| PubMed ID: 17071594	2006
Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbumin-challenged OTII mice. Blood\| PubMed ID: 17197430	2007
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. Journal of leukocyte biology\| PubMed ID: 17307864	2007
TNF can contribute to multiple features of ovalbumin-induced allergic inflammation of the airways in mice. The Journal of allergy and clinical immunology\| PubMed ID: 17336618	2007
Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cells. Blood\| PubMed ID: 17341663	2007
Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice. The Journal of allergy and clinical immunology\| PubMed ID: 17482668	2007
Mast cells in the promotion and limitation of chronic inflammation. Immunological reviews\| PubMed ID: 17498068	2007
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Blood\| PubMed ID: 17620455	2007
IL-33 can promote survival, adhesion and cytokine production in human mast cells. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 17700564	2007
Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nature immunology\| PubMed ID: 17767162	2007
IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals. Journal of leukocyte biology\| PubMed ID: 17881510	2007
Mast cells: versatile regulators of inflammation, tissue remodeling, host defense and homeostasis. Journal of dermatological science\| PubMed ID: 18024086	2008
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. Nature medicine\| PubMed ID: 18376408	2008
Basophils are back! Immunity\| PubMed ID: 18400194	2008
Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nature reviews. Immunology\| PubMed ID: 18483499	2008
The development of allergic inflammation. Nature\| PubMed ID: 18650915	2008
Rabaptin-5 regulates receptor expression and functional activation in mast cells. Blood\| PubMed ID: 18698003	2008
Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. The Journal of experimental medicine\| PubMed ID: 18794339	2008
New developments in mast cell biology. Nature immunology\| PubMed ID: 18936782	2008
IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 18975389	2008
Anaphylaxis to a self-peptide in the absence of mast cells or histamine. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 19188909	2009
The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 19818646	2010
Pillars article: fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient w/wv mice. Evidence that... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19923473	2009
Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice. The American journal of pathology\| PubMed ID: 20035049	2010
Localization of anionic constituents in mast cell granules of brachymorphic (bm/bm) mice by using avidin-conjugated colloidal gold. Cell and tissue research\| PubMed ID: 20127366	2010
Evidence that vitamin D(3) promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice. The Journal of experimental medicine\| PubMed ID: 20194632	2010
Distinguishing mast cell and granulocyte differentiation at the single-cell level. Cell stem cell\| PubMed ID: 20362540	2010
Regulation of secretory granule size by the precise generation and fusion of unit granules. Journal of cellular and molecular medicine\| PubMed ID: 20406331	2010
Anaphylaxis: mechanisms of mast cell activation. Chemical immunology and allergy\| PubMed ID: 20519881	2010
Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity. European journal of immunology\| PubMed ID: 20583030	2010
Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice. The American journal of pathology\| PubMed ID: 20829437	2010
Antiinflammatory and immunosuppressive functions of mast cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20941613	2011
Basophil CD203c levels are increased at baseline and can be used to monitor omalizumab treatment in subjects with nut allergy. International archives of allergy and immunology\| PubMed ID: 20975283	2011
The role of mast cells in atrial natriuretic peptide-induced cutaneous inflammation. Regulatory peptides\| PubMed ID: 21130119	2011
Evidence that the endothelin A receptor can enhance IgE-dependent anaphylaxis in mice. The Journal of allergy and clinical immunology\| PubMed ID: 21555149	2011
Mast cells and immunoregulation/immunomodulation. Advances in experimental medicine and biology\| PubMed ID: 21713658	2011
Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma. The Journal of clinical investigation\| PubMed ID: 21737883	2011
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice. The Journal of clinical investigation\| PubMed ID: 21926462	2011
Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice. Blood\| PubMed ID: 22001390	2011
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils. Nature immunology\| PubMed ID: 22012443	2011
Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients. Journal of clinical immunology\| PubMed ID: 22350221	2012
IgE and mast cells in allergic disease. Nature medicine\| PubMed ID: 22561833	2012
Critical role of P1-Runx1 in mouse basophil development. Blood\| PubMed ID: 22611151	2012
Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice. The Journal of allergy and clinical immunology\| PubMed ID: 22728083	2013
The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis. The American journal of pathology\| PubMed ID: 22901752	2012
Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 22906983	2012
New models for analyzing mast cell functions in vivo. Trends in immunology\| PubMed ID: 23127755	2012
Evidence that mast cells are not required for healing of splinted cutaneous excisional wounds in mice. PloS one\| PubMed ID: 23544053	2013
PLA2G3 promotes mast cell maturation and function. Nature immunology\| PubMed ID: 23685814	2013
Mast cells are required for full expression of allergen/SEB-induced skin inflammation. The Journal of investigative dermatology\| PubMed ID: 23752044	2013
Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells. The Journal of allergy and clinical immunology\| PubMed ID: 23810240	2013
Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice. The Journal of allergy and clinical immunology\| PubMed ID: 23915716	2013
Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cells. Blood\| PubMed ID: 24030387	2013
A beneficial role for immunoglobulin E in host defense against honeybee venom. Immunity\| PubMed ID: 24210352	2013
Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. The Journal of allergy and clinical immunology\| PubMed ID: 24461581	2014
[An allergic response to fight against venoms]. Médecine sciences : M/S\| PubMed ID: 24572105	2014
Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3). The Journal of allergy and clinical immunology\| PubMed ID: 24636474	2014
Mast cells: potential positive and negative roles in tumor biology. Cancer immunology research\| PubMed ID: 24777963	2013
Rethinking the potential roles of mast cells in skin wound healing and bleomycin-induced skin fibrosis. The Journal of investigative dermatology\| PubMed ID: 24924762	2014
Contribution of mast cell-derived interleukin-1β to uric acid crystal-induced acute arthritis in mice. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 24943488	2014
Evidence that meningeal mast cells can worsen stroke pathology in mice. The American journal of pathology\| PubMed ID: 25134760	2014
Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation. The Journal of investigative dermatology\| PubMed ID: 25209389	2015
A Balanced Look at the Implications of Genomic (and Other "Omics") Testing for Disease Diagnosis and Clinical Care. Genes\| PubMed ID: 25257203	2014
Potential effector and immunoregulatory functions of mast cells in mucosal immunity. Mucosal immunology\| PubMed ID: 25669149	2015
Approaches for analyzing the roles of mast cells and their proteases in vivo. Advances in immunology\| PubMed ID: 25727288	2015
Computational Pathology: A Path Ahead. Archives of pathology & laboratory medicine\| PubMed ID: 26098131	2016
An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers. Immunity\| PubMed ID: 26200013	2015
Testing the 'toxin hypothesis of allergy': mast cells, IgE, and innate and acquired immune responses to venoms. Current opinion in immunology\| PubMed ID: 26210895	2015
SnapShot: Integrated Type 2 Immune Responses. Immunity\| PubMed ID: 26287685	2015
Editorial overview: Allergy and hypersensitivity: New developments in allergy and type 2 immunity: never a dull moment. Current opinion in immunology\| PubMed ID: 26337485	2015
IgE antibodies, FcεRIα, and IgE-mediated local anaphylaxis can limit snake venom toxicity. The Journal of allergy and clinical immunology\| PubMed ID: 26410782	2016
Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1. Stem cells and development\| PubMed ID: 26422691	2016
The adherens junctions control susceptibility to Staphylococcus aureus α-toxin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26489655	2015
Mast cells and IgE in defense against venoms: Possible "good side" of allergy? Allergology international : official journal of the Japanese Society of Allergology\| PubMed ID: 26666482	2016
The Mast Cell-IgE Paradox: From Homeostasis to Anaphylaxis. The American journal of pathology\| PubMed ID: 26776074	2016
Successful immunotherapy induces previously unidentified allergen-specific CD4+ T-cell subsets. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26811452	2016
Molecular and cellular mechanisms of food allergy and food tolerance. The Journal of allergy and clinical immunology\| PubMed ID: 27059726	2016
Toward precision medicine and health: Opportunities and challenges in allergic diseases. The Journal of allergy and clinical immunology\| PubMed ID: 27155026	2016
IgE and mast cells in host defense against parasites and venoms. Seminars in immunopathology\| PubMed ID: 27225312	2016
IgG subclasses determine pathways of anaphylaxis in mice. The Journal of allergy and clinical immunology\| PubMed ID: 27246523	2017
Assessing basophil activation by using flow cytometry and mass cytometry in blood stored 24 hours before analysis. The Journal of allergy and clinical immunology\| PubMed ID: 27527263	2017
Pathways of immediate hypothermia and leukocyte infiltration in an adjuvant-free mouse model of anaphylaxis. The Journal of allergy and clinical immunology\| PubMed ID: 27555460	2017
Different activation signals induce distinct mast cell degranulation strategies. The Journal of clinical investigation\| PubMed ID: 27643442	2016
The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation. Nature communications\| PubMed ID: 27786273	2016
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. The Journal of clinical investigation\| PubMed ID: 27820702	2016
Neutrophils are not required for resolution of acute gouty arthritis in mice. Nature medicine\| PubMed ID: 27923029	2016
A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice. Nature communications\| PubMed ID: 27982078	2016
Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future. Cancer research\| PubMed ID: 28254862	2017
Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4 T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis. Infection and immunity\| PubMed ID: 28264908	2017
Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling. Cell\| PubMed ID: 28283060	2017
Association of Clinical Reactivity with Sensitization to Allergen Components in Multifood-Allergic Children. The journal of allergy and clinical immunology. In practice\| PubMed ID: 28351786	2017
Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide. The Journal of experimental medicine\| PubMed ID: 28385925	2017
Reply. The Journal of allergy and clinical immunology\| PubMed ID: 28410741	2017
Imaging protective mast cells in living mice during severe contact hypersensitivity. JCI insight\| PubMed ID: 28469089	2017
Mast Cells and KIT as Potential Therapeutic Targets in Severe Asthma. The New England journal of medicine\| PubMed ID: 28514622	2017
A new fluorescent-avidin-based method for quantifying basophil activation in whole blood. The Journal of allergy and clinical immunology\| PubMed ID: 28606590	2017
Human mast cells as antigen-presenting cells: When is this role important in vivo? The Journal of allergy and clinical immunology\| PubMed ID: 28624609	2018
The pathophysiology of anaphylaxis. The Journal of allergy and clinical immunology\| PubMed ID: 28780941	2017
Mast Cells and IgE can Enhance Survival During Innate and Acquired Host Responses to Venoms. Transactions of the American Clinical and Climatological Association\| PubMed ID: 28790503	2017
Immune monitoring for precision medicine in allergy and asthma. Current opinion in immunology\| PubMed ID: 28889067	2017
The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice. PloS one\| PubMed ID: 28982129	2017
Rab5 is critical for SNAP23 regulated granule-granule fusion during compound exocytosis. Scientific reports\| PubMed ID: 29127297	2017
Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal. EBioMedicine\| PubMed ID: 29203377	2017
Anti-IgE treatment with oral immunotherapy in multifood allergic participants: a double-blind, randomised, controlled trial. The lancet. Gastroenterology & hepatology\| PubMed ID: 29242014	2018
Isotype-specific agglutination-PCR (ISAP): A sensitive and multiplex method for measuring allergen-specific IgE. The Journal of allergy and clinical immunology\| PubMed ID: 29248495	2018
Food allergy and omics. The Journal of allergy and clinical immunology\| PubMed ID: 29307411	2018
Mast cells as sources of cytokines, chemokines, and growth factors. Immunological reviews\| PubMed ID: 29431212	2018
Thirdhand smoke component can exacerbate a mouse asthma model through mast cells. The Journal of allergy and clinical immunology\| PubMed ID: 29678746	2018
Development of a tool predicting severity of allergic reaction during peanut challenge. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology\| PubMed ID: 29709643	2018
Between hype and hope: whole-genome sequencing in clinical medicine. Personalized medicine\| PubMed ID: 29758791	2012
Genomics in the clinic: ethical and policy challenges in clinical next-generation sequencing programs at early adopter USA institutions. Personalized medicine\| PubMed ID: 29771644	2015
Effect of Dietary Fiber and Metabolites on Mast Cell Activation and Mast Cell-Associated Diseases. Frontiers in immunology\| PubMed ID: 29910798	2018