Yasuyuki Sakai

Center for International Research on Integrative Biomedical System, The University of Tokyo

Affiliated withThe University of Tokyo University of Tokyo the university of tokyo

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 14	2015
Publication title Cited by 6	2019

Other Publications

Article	Year
Muscarinic receptor activation in the lumbosacral spinal cord ameliorates bladder irritation in rat cystitis models. BJU international\| PubMed ID: 19466955	2009
Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane. Tissue engineering. Part C, Methods\| PubMed ID: 19563254	2010
A rapid and simple evaluation system for gas toxicity using luminous bacteria entrapped by a polyion complex membrane. Chemosphere\| PubMed ID: 19716582	2009
Simultaneous evaluation of toxicities using a mammalian cell array chip prepared by photocatalytic lithography. Analytica chimica acta\| PubMed ID: 19808118	2009
Simple prophylactic procedure of inguinal hernia after radical retropubic prostatectomy: isolation of the spermatic cord. International journal of urology : official journal of the Japanese Urological Association\| PubMed ID: 19811549	2009
A micropatterned cell array with an integrated oxygen-sensitive fluorescent membrane. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology\| PubMed ID: 19862410	2009
Initial experience of diffusion-weighted magnetic resonance imaging to assess therapeutic response to induction chemoradiotherapy against muscle-invasive bladder cancer. Urology\| PubMed ID: 19914691	2010
On-chip single embryo coculture with microporous-membrane-supported endometrial cells. IEEE transactions on nanobioscience\| PubMed ID: 20142147	2009
Spontaneous formation of stably-attached and 3D-organized hepatocyte aggregates on oxygen-permeable polydimethylsiloxane membranes having 3D microstructures. Biomedical microdevices\| PubMed ID: 20174871	2010
Modulation of hepatocarcinoma cell morphology and activity by parylene-C coating on PDMS. PloS one\| PubMed ID: 20300511	2010
Transplantation of a fetal liver cell-loaded hyaluronic acid sponge onto the mesentery recovers a Wilson's disease model rat. Journal of biochemistry\| PubMed ID: 20562412	2010
Microfibrillated cellulose sheets coating oxygen-permeable PDMS membranes induce rat hepatocytes 3D aggregation into stably-attached 3D hemispheroids. Journal of biomaterials science. Polymer edition\| PubMed ID: 20626957	2011
Electrochemical biosensor for the detection of H2O2 from living cancer cells based on ZnO nanosheets. Analytica chimica acta\| PubMed ID: 20685417	2010
Enhanced effects of secreted soluble factor preserve better pluripotent state of embryonic stem cell culture in a membrane-based compartmentalized micro-bioreactor. Biomedical microdevices\| PubMed ID: 20809277	2010
Cytotoxicity evaluation of reactive metabolites using rat liver homogenate microsome-encapsulated alginate gel microbeads. Journal of bioscience and bioengineering\| PubMed ID: 21239224	2011
Programming an in vitro DNA oscillator using a molecular networking strategy. Molecular systems biology\| PubMed ID: 21283142	2011
Towards single cell heat shock response by accurate control on thermal confinement with an on-chip microwire electrode. Lab on a chip\| PubMed ID: 21394336	2011
Phthalocyanine-based fluorescence probes for detecting ascorbic acid: phthalocyaninatosilicon covalently linked to TEMPO radicals. Chemical communications (Cambridge, England)\| PubMed ID: 21423994	2011
Establishment of self-organization system in rapidly formed multicellular heterospheroids. Biomaterials\| PubMed ID: 21620469	2011
Gas-permeable membranes and co-culture with fibroblasts enable high-density hepatocyte culture as multilayered liver tissues. Biotechnology progress\| PubMed ID: 21630487	2011
Kinetic modelling of in vitro cell-based assays to characterize non-specific bindings and ADME processes in a static and a perfused fluidic system. Toxicology letters\| PubMed ID: 21723928	2011
Integration of a pump and an electrical sensor into a membrane-based PDMS microbioreactor for cell culture and drug testing. Biomedical microdevices\| PubMed ID: 21728068	2011
Bile canaliculi formation by aligning rat primary hepatocytes in a microfluidic device. Biomicrofluidics\| PubMed ID: 21799718	2011
Use of liposome encapsulated hemoglobin as an oxygen carrier for fetal and adult rat liver cell culture. Journal of bioscience and bioengineering\| PubMed ID: 21813323	2011
Engineering of implantable liver tissues. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22167650	2012
Rapid aggregation of heterogeneous cells and multiple-sized microspheres in methylcellulose medium. Biomaterials\| PubMed ID: 22440047	2012
Enhanced bile canaliculi formation enabling direct recovery of biliary metabolites of hepatocytes in 3D collagen gel microcavities. Lab on a chip\| PubMed ID: 22441571	2012
Direct synthesis of cup-stacked carbon nanofiber microspheres by the catalytic pyrolysis of poly(ethylene glycol). Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 22591331	2012
Induction of alternative fate other than default neuronal fate of embryonic stem cells in a membrane-based two-chambered microbioreactor by cell-secreted BMP4. Biomicrofluidics\| PubMed ID: 22662099	2012
Ubiquitin-specific peptidase 46 (Usp46) regulates mouse immobile behavior in the tail suspension test through the GABAergic system. PloS one\| PubMed ID: 22720038	2012
Direct oxygen supply with polydimethylsiloxane (PDMS) membranes induces a spontaneous organization of thick heterogeneous liver tissues from rat fetal liver cells in vitro. Cell transplantation\| PubMed ID: 22793047	2012
Spatiotemporally controlled delivery of soluble factors for stem cell differentiation. Lab on a chip\| PubMed ID: 22968416	2012
Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes. Scientific reports\| PubMed ID: 23378928	2013
Importance of a diffusion-dominant small volume to activate cell-secreted soluble factor signaling in embryonic stem cell culture in microbioreactors: a mathematical model based study. Journal of bioscience and bioengineering\| PubMed ID: 23434300	2013
Induced pluripotent stem cell-derived hepatocytes as an alternative to human adult hepatocytes. Journal of stem cells\| PubMed ID: 23550341	2012
Biliary epithelial cells play an essential role in the reconstruction of hepatic tissue with a functional bile ductular network. Tissue engineering. Part A\| PubMed ID: 23745513	2013
First experience of active surveillance before systemic target therapy in patients with metastatic renal cell carcinoma. Urology\| PubMed ID: 23806397	2013
Combination of microwell structures and direct oxygenation enables efficient and size-regulated aggregate formation of an insulin-secreting pancreatic β-cell line. Biotechnology progress\| PubMed ID: 24265060	2014
Image-based evaluations of distribution and cytotoxicity of Irinotecan (CPT-11) in a multi-compartment micro-cell coculture device. Journal of bioscience and bioengineering\| PubMed ID: 24374121	2014
A novel 3-dimensional image analysis system for case-specific kidney anatomy and surgical simulation to facilitate clampless partial nephrectomy. Urology\| PubMed ID: 24468517	2014
Proliferation, morphology, and pluripotency of mouse induced pluripotent stem cells in three different types of alginate beads for mass production. Biotechnology progress\| PubMed ID: 24585713	2014
Risk stratification for bladder recurrence of upper urinary tract urothelial carcinoma after radical nephroureterectomy. BJU international\| PubMed ID: 24612074	2015
Electrochemical properties of oxygenated cup-stacked carbon nanofiber-modified electrodes. Physical chemistry chemical physics : PCCP\| PubMed ID: 24817367	2014
Adhesion of pancreatic cancer cells in a liver-microvasculature mimicking coculture correlates with their propensity to form liver-specific metastasis in vivo. BioMed research international\| PubMed ID: 24900957	2014
Equivalent survival and improved preservation of renal function after distal ureterectomy compared with nephroureterectomy in patients with urothelial carcinoma of the distal ureter: a prope... International journal of urology : official journal of the Japanese Urological Association\| PubMed ID: 25041040	2014
The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes. Biotechnology progress\| PubMed ID: 25078970	2014
Bimodal pattern of the impact of body mass index on cancer-specific survival of upper urinary tract urothelial carcinoma patients. Anticancer research\| PubMed ID: 25275074	2014
An on-chip small intestine-liver model for pharmacokinetic studies. Journal of laboratory automation\| PubMed ID: 25385717	2015
Preparation of uniform-sized hemoglobin-albumin microspheres as oxygen carriers by Shirasu porous glass membrane emulsification technique. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 25635614	2015
Clinical Value of F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Upper Tract Urothelial Carcinoma: Impact on Detection of Metastases and Patient Management. Urologia internationalis\| PubMed ID: 26044598	2015
Organ/body-on-a-chip based on microfluidic technology for drug discovery. Drug metabolism and pharmacokinetics\| PubMed ID: 29175062	2018
Enhanced hepatic differentiation of human iPS cells using gas permeable membrane. Tissue engineering. Part A\| PubMed ID: 30141379	2018