Bertrand Tavitian

PARCC - INSERM U970, Université Paris Descartes

Affiliated withUniversité Paris Descartes Université Paris Descartes Sorbonne Paris Cité Hôpital Européen Georges Pompidou

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 14	2016
Publication title Cited by 13	2017

Other Publications

Article	Year
Characterization of a synthetic anionic vector for oligonucleotide delivery using in vivo whole body dynamic imaging. Pharmaceutical research\| PubMed ID: 12033366	2002
Labelled oligonucleotides as radiopharmaceuticals: pitfalls, problems and perspectives. Current pharmaceutical design\| PubMed ID: 12052206	2002
Nucleic acid aptamers in cancer medicine. FEBS letters\| PubMed ID: 12297271	2002
A new animal model for the imaging of melanoma: correlation of FDG PET with clinical outcome, macroscopic aspect and histological classification in Melanoblastoma-bearing Libechov Minipigs. European journal of nuclear medicine and molecular imaging\| PubMed ID: 12682788	2003
Modulation of the pharmacokinetic properties of PNA: preparation of galactosyl, mannosyl, fucosyl, N-acetylgalactosaminyl, and N-acetylglucosaminyl derivatives of aminoethylglycine peptide n... Bioconjugate chemistry\| PubMed ID: 13129397	2003
Design and synthesis of a new [18F]fluoropyridine-based haloacetamide reagent for the labeling of oligonucleotides: 2-bromo-N-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]acetamide. Bioconjugate chemistry\| PubMed ID: 15149190	2004
In vivo biodistribution and pharmacokinetics of 18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals. European journal of nuclear medicine and molecular imaging\| PubMed ID: 15614506	2005
1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and prote... Bioconjugate chemistry\| PubMed ID: 15769096	2005
Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS biology\| PubMed ID: 15769183	2005
Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 16210395	2006
An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation. Molecular cancer research : MCR\| PubMed ID: 16849523	2006
In vivo tumor targeting using a novel intestinal pathogen-based delivery approach. Cancer research\| PubMed ID: 16849571	2006
Comparison of different strategies to select aptamers against a transmembrane protein target. Oligonucleotides\| PubMed ID: 17155908	2006
11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 17401094	2007
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma. Gastroenterology\| PubMed ID: 17408651	2007
In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors. Glia\| PubMed ID: 17680643	2007
Binding of an aptamer to the N-terminal fragment of VCAM-1. Bioorganic & medicinal chemistry letters\| PubMed ID: 17905582	2007
Non-invasive in vivo imaging of calcium signaling in mice. PloS one\| PubMed ID: 17912353	2007
Segmentation of rodent whole-body dynamic PET images: an unsupervised method based on voxel dynamics. IEEE transactions on medical imaging\| PubMed ID: 18334430	2008
Molecular imaging study on in vivo distribution and pharmacokinetics of modified small interfering RNAs (siRNAs). Oligonucleotides\| PubMed ID: 18729822	2008
Fluorine-18-labeled phospholipid quantum dot micelles for in vivo multimodal imaging from whole body to cellular scales. Bioconjugate chemistry\| PubMed ID: 18754572	2008
Internal radiotherapy of liver cancer with rat hepatocarcinoma-intestine-pancreas gene as a liver tumor-specific promoter. Human gene therapy\| PubMed ID: 18759560	2008
Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers. European journal of nuclear medicine and molecular imaging\| PubMed ID: 18828015	2008
Distribution and bioactivity of the Ret-specific D4 aptamer in three-dimensional collagen gel cultures. Molecular cancer therapeutics\| PubMed ID: 18852141	2008
New device for real-time bioluminescence imaging in moving rodents. Journal of biomedical optics\| PubMed ID: 19021415	2008
In vivo tumor targeting by the B-subunit of shiga toxin. Molecular imaging\| PubMed ID: 19123994	2008
Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 19223401	2009
In vivo imaging of oligonucleotidic aptamers. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19377991	2009
Membrane-type 4 matrix metalloproteinase (MT4-MMP) induces lung metastasis by alteration of primary breast tumour vascular architecture. Journal of cellular and molecular medicine\| PubMed ID: 19426156	2009
Darwinian molecular imaging. European journal of nuclear medicine and molecular imaging\| PubMed ID: 19557411	2009
Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway. Proteomics\| PubMed ID: 19639598	2009
PET imaging of medullary thyroid carcinoma in MEN2A transgenic mice using 6-[(18)F]F-L-DOPA. European journal of nuclear medicine and molecular imaging\| PubMed ID: 19655139	2010
Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 19794397	2010
In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution. Blood\| PubMed ID: 19797522	2010
Similar expression profiles of a core of genes and proteins in cells that have acquired a metastatic phenotype, genetically or by in vivo evolution. Clinical & experimental metastasis\| PubMed ID: 19904617	2010
Differential SELEX in human glioma cell lines. PloS one\| PubMed ID: 19956692	2009
Radioisotopic imaging of neuroinflammation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 20008995	2010
In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model. European journal of nuclear medicine and molecular imaging\| PubMed ID: 20069292	2010
[Molecular approaches in experimental neuroimaging]. Bulletin de l'Academie nationale de medecine\| PubMed ID: 20120273	2009
Reduced PBR/TSPO expression after minocycline treatment in a rat model of focal cerebral ischemia: a PET study using [(18)F]DPA-714. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 20383592	2011
Metastasis-focused cell-based SELEX generates aptamers inhibiting cell migration and invasion. International journal of cancer\| PubMed ID: 20473891	2011
In vivo validation of free-space fluorescence tomography using nuclear imaging. Optics letters\| PubMed ID: 20847766	2010
In vivo imaging of neuroinflammation in the rodent brain with [11C]SSR180575, a novel indoleacetamide radioligand of the translocator protein (18 kDa). European journal of nuclear medicine and molecular imaging\| PubMed ID: 20936410	2011
Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding. RNA (New York, N.Y.)\| PubMed ID: 20962041	2010
Single photon emission computed tomography/positron emission tomography imaging and targeted radionuclide therapy of melanoma: new multimodal fluorinated and iodinated radiotracers. Journal of medicinal chemistry\| PubMed ID: 21417462	2011
Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer. Molecular pharmaceutics\| PubMed ID: 21417480	2011
Synthesis of 6-[¹⁸F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET. Bioorganic & medicinal chemistry letters\| PubMed ID: 21741237	2011
Genotype specific age related changes in a transgenic rat model of Huntington's disease. NeuroImage\| PubMed ID: 21767653	2011
Realizing the full potential of PET for measuring the biodistribution of novel anticancer agents. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 21824989	2011
Tumor-targeted polydiacetylene micelles for in vivo imaging and drug delivery. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21837631	2011
The translocator protein ligand [¹⁸F]DPA-714 images glioma and activated microglia in vivo. European journal of nuclear medicine and molecular imaging\| PubMed ID: 22270507	2012
In vivo evidence that the increase in matrix metalloproteinase activity occurs early after cerebral ischemia. Molecular imaging\| PubMed ID: 22418024	2012
Imaging of perfusion, angiogenesis, and tissue elasticity after stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 22491156	2012
Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22539835	2012
Noninvasive molecular imaging of neuroinflammation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 22549622	2012
Co-registration of glucose metabolism with positron emission tomography and vascularity with fluorescent diffuse optical tomography in mouse tumors. EJNMMI research\| PubMed ID: 22564761	2012
Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 22689925	2012
Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases. Insights into imaging\| PubMed ID: 22696004	2012
Comparison of 18F-fluoro-deoxy-glucose, 18F-fluoro-methyl-choline, and 18F-DPA714 for positron-emission tomography imaging of leukocyte accumulation in the aortic wall of experimental abdomi... Journal of vascular surgery\| PubMed ID: 22726755	2012
Fusion of [(18)F]FDG PET with fluorescence diffuse optical tomography to improve validation of probes and tumor imaging. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 22927057	2013
Synthetic lipid nanoparticles targeting steroid organs. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 24071507	2013
The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 24212976	2013
CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors. Cell cycle (Georgetown, Tex.)\| PubMed ID: 24626200	2014
In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET. Nuclear medicine and biology\| PubMed ID: 25537727	2015
Comparative biodistribution in mice of cyanine dyes loaded in lipid nanoparticles. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 25805562	2015
Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 26126867	2015
Monitoring therapeutic efficacy of sunitinib using [(18)F]FDG and [(18)F]FMISO PET in an immunocompetent model of luminal B (HER2-positive)-type mammary carcinoma. BMC cancer\| PubMed ID: 26198000	2015
In Vivo Detection of Succinate by Magnetic Resonance Spectroscopy as a Hallmark of SDHx Mutations in Paraganglioma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26490314	2015
Multimodal In Vivo Imaging of Tumorigenesis and Response to Chemotherapy in a Transgenic Mouse Model of Mammary Cancer. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 26630973	2015
Cell Sheet Transplantation for Esophageal Stricture Prevention after Endoscopic Submucosal Dissection in a Porcine Model. PloS one\| PubMed ID: 26930409	2016
Designing 3D Mesenchymal Stem Cell Sheets Merging Magnetic and Fluorescent Features: When Cell Sheet Technology Meets Image-Guided Cell Therapy. Theranostics\| PubMed ID: 27022420	2016
Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma. Integrative cancer therapies\| PubMed ID: 27130721	2016
Imaging Reactive Oxygen Species-Induced Modifications in Living Systems. Antioxidants & redox signaling\| PubMed ID: 27139586	2016
Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters. Magnetic resonance in chemistry : MRC\| PubMed ID: 27859555	2016
Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis. Molecular metabolism\| PubMed ID: 28123938	2017