Iain A. Drummond

Department of Medicine and Genetics, Harvard Medical School

Affiliated withHarvard Medical School Massachusetts General Hospital

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 83	2010
Publication title Cited by 27	2015

Other Publications

Article	Year
Endothelial signaling in kidney morphogenesis: a role for hemodynamic forces. Current biology : CB\| PubMed ID: 11909536	2002
A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish. Development (Cambridge, England)\| PubMed ID: 12421721	2002
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nature genetics\| PubMed ID: 12872123	2003
Zebrafish kidney development. Methods in cell biology\| PubMed ID: 15602890	2004
Kidney development and disease in the zebrafish. Journal of the American Society of Nephrology : JASN\| PubMed ID: 15647335	2005
Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (Cambridge, England)\| PubMed ID: 15790966	2005
roundabout4 is essential for angiogenesis in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15849270	2005
Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization. American journal of physiology. Renal physiology\| PubMed ID: 15914778	2005
Organization of the pronephric filtration apparatus in zebrafish requires Nephrin, Podocin and the FERM domain protein Mosaic eyes. Developmental biology\| PubMed ID: 16102746	2005
Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16943304	2006
Dynamic expression of the osmosensory channel trpv4 in multiple developing organs in zebrafish. Gene expression patterns : GEP\| PubMed ID: 17161658	2007
New functions for a vertebrate Rho guanine nucleotide exchange factor in ciliated epithelia. Development (Cambridge, England)\| PubMed ID: 17267448	2007
Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros. Development (Cambridge, England)\| PubMed ID: 17287248	2007
The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation. Molecular biology of the cell\| PubMed ID: 17761526	2007
Expression of trpC1 and trpC6 orthologs in zebrafish. Gene expression patterns : GEP\| PubMed ID: 18378501	2008
Some assembly required: renal hypodysplasia and the problem with faulty parts. Journal of the American Society of Nephrology : JASN\| PubMed ID: 18385415	2008
odd skipped related1 reveals a novel role for endoderm in regulating kidney versus vascular cell fate. Development (Cambridge, England)\| PubMed ID: 18787069	2008
Collective cell migration drives morphogenesis of the kidney nephron. PLoS biology\| PubMed ID: 19127979	2009
Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish. American journal of physiology. Cell physiology\| PubMed ID: 19625604	2009
Fluid flow and guidance of collective cell migration. Cell adhesion & migration\| PubMed ID: 20234192	2010
The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation. Disease models & mechanisms\| PubMed ID: 20335443	2010
Polyglutamylation and the fleer gene. Methods in cell biology\| PubMed ID: 20362098	2009
Cloning and characterization of a zebrafish homologue of human AQP1: a bifunctional water and gas channel. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 20739606	2010
The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20937855	2010
Zebrafish kidney development. Methods in cell biology\| PubMed ID: 21111220	2010
Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility. The Journal of biological chemistry\| PubMed ID: 21262966	2011
Polycystins, focal adhesions and extracellular matrix interactions. Biochimica et biophysica acta\| PubMed ID: 21396443	2011
CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia. Development (Cambridge, England)\| PubMed ID: 21752935	2011
Cilia functions in development. Current opinion in cell biology\| PubMed ID: 22226236	2012
Mutation mapping and identification by whole-genome sequencing. Genome research\| PubMed ID: 22555591	2012
CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature genetics\| PubMed ID: 22581229	2012
Live imaging kidney development in zebrafish. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22639251	2012
Mechanical stretch and PI3K signaling link cell migration and proliferation to coordinate epithelial tubule morphogenesis in the zebrafish pronephros. PloS one\| PubMed ID: 22815719	2012
Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell reports\| PubMed ID: 22840396	2012
Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis. Journal of the American Society of Nephrology : JASN\| PubMed ID: 22904347	2012
The cilium in lights: new views of an ancient organelle. BMC biology\| PubMed ID: 23822867	2013
ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6. American journal of human genetics\| PubMed ID: 23891469	2013
odd-skipped related 2 is required for fin chondrogenesis in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 23913342	2013
Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia. American journal of human genetics\| PubMed ID: 24094744	2013
A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. Human mutation\| PubMed ID: 24166846	2014
A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12. Disease models & mechanisms\| PubMed ID: 24311731	2014
Modulation of the secretory pathway rescues zebrafish polycystic kidney disease pathology. Journal of the American Society of Nephrology : JASN\| PubMed ID: 24627348	2014
osr1 is required for podocyte development downstream of wt1a. Journal of the American Society of Nephrology : JASN\| PubMed ID: 24722440	2014
Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function. Molecular biology of the cell\| PubMed ID: 24743595	2014
Collective epithelial migration drives kidney repair after acute injury. PloS one\| PubMed ID: 25010471	2014
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nature cell biology\| PubMed ID: 25173977	2014
Odd skipped related 1 is a negative feedback regulator of nodal-induced endoderm development. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 25233796	2014
Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity. Genome research\| PubMed ID: 25273069	2015
Nephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transition. PLoS genetics\| PubMed ID: 25340510	2014
The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule. PLoS genetics\| PubMed ID: 25838181	2015