Eva L. Feldman

Department of Neurology, University of Michigan

Affiliated withUniversity of Michigan Michigan Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 11	2010
Publication title	2017
Publication title Cited by 12	2020

Other Publications

Article	Year
Schwann cell caveolin-1 expression increases during myelination and decreases after axotomy. Glia\| PubMed ID: 11968057	2002
Insulin-like growth factor I prevents mannitol-induced degradation of focal adhesion kinase and Akt. The Journal of biological chemistry\| PubMed ID: 12011046	2002
N-Myc and Bcl-2 coexpression induces MMP-2 secretion and activation in human neuroblastoma cells. Oncogene\| PubMed ID: 12085233	2002
Control of cell survival by IGF signaling pathways. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 12175651	2002
Update on diabetic neuropathy. Current opinion in neurology\| PubMed ID: 12352003	2002
Signaling mechanisms that regulate actin-based motility processes in the nervous system. Journal of neurochemistry\| PubMed ID: 12390511	2002
High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12409316	2002
Neuronal survival following remote adenovirus gene delivery. Journal of neurosurgery\| PubMed ID: 12450285	2002
Intraneural colchicine inhibition of adenoviral and adeno-associated viral vector remote spinal cord gene delivery. Neurosurgery\| PubMed ID: 12535368	2003
Oxidative stress and diabetic neuropathy: a new understanding of an old problem. The Journal of clinical investigation\| PubMed ID: 12588877	2003
N-Myc overexpression leads to decreased beta1 integrin expression and increased apoptosis in human neuroblastoma cells. Oncogene\| PubMed ID: 12730680	2003
Substrate patterning: an emerging technology for the study of neuronal behavior. Experimental neurology\| PubMed ID: 14597331	2003
Microvascular complications of impaired glucose tolerance. Diabetes\| PubMed ID: 14633845	2003
Guidelines for the diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy. Journal of the peripheral nervous system : JPNS\| PubMed ID: 14641652	2003
Degradation and dephosphorylation of focal adhesion kinase during okadaic acid-induced apoptosis in human neuroblastoma cells. Neoplasia (New York, N.Y.)\| PubMed ID: 14670178	2003
Adeno-associated viral vector gene expression in the adult rat spinal cord following remote vector delivery. Neurobiology of disease\| PubMed ID: 14678769	2003
Insulin-like growth factor-I signaling in human neuroblastoma cells. Oncogene\| PubMed ID: 14712218	2004
The role of growth factors in diabetic peripheral neuropathy. Journal of the peripheral nervous system : JPNS\| PubMed ID: 14871451	2004
Applying database technology to clinical and basic research bioinformatics projects. Journal of integrative neuroscience\| PubMed ID: 15011271	2003
Neuroinflammation, COX-2, and ALS--a dual role? Experimental neurology\| PubMed ID: 15081582	2004
IGF-I prevents glutamate-induced motor neuron programmed cell death. Neurobiology of disease\| PubMed ID: 15193297	2004
New insights into the mechanisms of diabetic neuropathy. Reviews in endocrine & metabolic disorders\| PubMed ID: 15211094	2004
Integrin expression regulates neuroblastoma attachment and migration. Neoplasia (New York, N.Y.)\| PubMed ID: 15256055	2004
Oxidative stress in the pathogenesis of diabetic neuropathy. Endocrine reviews\| PubMed ID: 15294884	2004
Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15319368	2004
Establishment, maintenance, and transfection of in vitro cultures of human retinal pigment epithelium. Methods in molecular medicine\| PubMed ID: 15492384	2005
In situ imaging of mitochondrial outer-membrane pores using atomic force microscopy. BioTechniques\| PubMed ID: 15517968	2004
Polyneuropathy with Impaired Glucose Tolerance: Implications for Diagnosis and Therapy. Current treatment options in neurology\| PubMed ID: 15610705	2005
Integrin-linked kinase complexes with caveolin-1 in human neuroblastoma cells. Biochemistry\| PubMed ID: 15654749	2005
Short-term hyperglycemia produces oxidative damage and apoptosis in neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15677696	2005
Differential regulation of insulin receptor substrate-1 degradation during mannitol and okadaic acid induced apoptosis in human neuroblastoma cells. Cellular signalling\| PubMed ID: 15722201	2005
Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes care\| PubMed ID: 15793206	2005
Insulin-like growth factors in the treatment of neurological disease. Endocrine development\| PubMed ID: 15879695	2005
Adeno-associated viral-mediated insulin-like growth factor delivery protects motor neurons in vitro. Neuromolecular medicine\| PubMed ID: 15970625	2004
Insulin-like growth factor I induces preferential degradation of insulin receptor substrate-2 through the phosphatidylinositol 3-kinase pathway in human neuroblastoma cells. Endocrinology\| PubMed ID: 16150916	2005
New developments in diabetic neuropathy. Current opinion in neurology\| PubMed ID: 16155445	2005
Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury. Antioxidants & redox signaling\| PubMed ID: 16356113	2005
Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion. Diabetes care\| PubMed ID: 16443884	2006
Longitudinal assessment of noninvasive positive pressure ventilation adjustments in ALS patients. Journal of the neurological sciences\| PubMed ID: 16631799	2006
Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiology of disease\| PubMed ID: 16684605	2006
Lifestyle intervention for pre-diabetic neuropathy. Diabetes care\| PubMed ID: 16732011	2006
Evaluation of sham non-invasive ventilation for randomized, controlled trials in ALS. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases\| PubMed ID: 16753973	2006
Insulin-like growth factor-I receptor expression regulates neuroblastoma metastasis to bone. Cancer research\| PubMed ID: 16818629	2006
Biomedical research: a culture in crisis? Nature clinical practice. Neurology\| PubMed ID: 16932493	2005
Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy. Nature clinical practice. Neurology\| PubMed ID: 17057749	2006
Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress. Endocrinology\| PubMed ID: 17095586	2007
Diabetic neuropathies. Practical neurology\| PubMed ID: 17430872	2007
Aligned electrospun nanofibers specify the direction of dorsal root ganglia neurite growth. Journal of biomedical materials research. Part A\| PubMed ID: 17508416	2007
Dysfunction of the recurrent laryngeal nerve and the potential of gene therapy. The Annals of otology, rhinology, and laryngology\| PubMed ID: 17672247	2007
Mouse models of diabetic neuropathy. Neurobiology of disease\| PubMed ID: 17804249	2007
SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy. Experimental neurology\| PubMed ID: 17927981	2007
Can drug screening lead to candidate therapies for testing in diabetic neuropathy? Antioxidants & redox signaling\| PubMed ID: 17961065	2008
Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function. Circulation research\| PubMed ID: 18174465	2008
Strategic approaches to developing drug treatments for ALS. Drug discovery today\| PubMed ID: 18190866	2008
Diabetic neuropathy. Current drug targets\| PubMed ID: 18220708	2008
Criteria for creating and assessing mouse models of diabetic neuropathy. Current drug targets\| PubMed ID: 18220709	2008
The antioxidant response as a drug target in diabetic neuropathy. Current drug targets\| PubMed ID: 18220717	2008
Membrane traffic and muscle: lessons from human disease. Traffic (Copenhagen, Denmark)\| PubMed ID: 18266915	2008
National Institute of Neurological Disorders and Stroke (NINDS): advances in understanding and treating neuropathy, 24-25 October 2006; Bethesda, Maryland. Journal of the peripheral nervous system : JPNS\| PubMed ID: 18346227	2008
Abnormal muscle spindle innervation and large-fiber neuropathy in diabetic mice. Diabetes\| PubMed ID: 18362211	2008
The design of electrospun PLLA nanofiber scaffolds compatible with serum-free growth of primary motor and sensory neurons. Acta biomaterialia\| PubMed ID: 18396117	2008
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) meeting summary: Advances toward measuring diabetic retinopathy and neuropathy: from the bench to the clinic and back... Journal of diabetes and its complications\| PubMed ID: 18413183	2009
Oxidative injury and neuropathy in diabetes and impaired glucose tolerance. Neurobiology of disease\| PubMed ID: 18424057	2008
Rosiglitazone treatment reduces diabetic neuropathy in streptozotocin-treated DBA/2J mice. Endocrinology\| PubMed ID: 18583417	2008
Insulin-like growth factor-I for the treatment of amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases\| PubMed ID: 18608100	2009
Kindlin-2 is required for myocyte elongation and is essential for myogenesis. BMC cell biology\| PubMed ID: 18611274	2008
Diabetic neuropathy: mechanisms to management. Pharmacology & therapeutics\| PubMed ID: 18616962	2008
Rosiglitazone reduces renal and plasma markers of oxidative injury and reverses urinary metabolite abnormalities in the amelioration of diabetic nephropathy. American journal of physiology. Renal physiology\| PubMed ID: 18667486	2008
Mechanisms of disease: the oxidative stress theory of diabetic neuropathy. Reviews in endocrine & metabolic disorders\| PubMed ID: 18709457	2008
Insulin-like growth factors in the peripheral nervous system. Endocrinology\| PubMed ID: 18719018	2008
The Utah Early Neuropathy Scale: a sensitive clinical scale for early sensory predominant neuropathy. Journal of the peripheral nervous system : JPNS\| PubMed ID: 18844788	2008
Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms. Antioxidants & redox signaling\| PubMed ID: 19072199	2009
Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS. Neurobiology of disease\| PubMed ID: 19135533	2009
SciMiner: web-based literature mining tool for target identification and functional enrichment analysis. Bioinformatics (Oxford, England)\| PubMed ID: 19188191	2009
Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy. PLoS genetics\| PubMed ID: 19197364	2009
Disorders of cranial nerves IX and X. Seminars in neurology\| PubMed ID: 19214937	2009
Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis. Apoptosis : an international journal on programmed cell death\| PubMed ID: 19259821	2009
Reliability of quantitative sudomotor axon reflex testing and quantitative sensory testing in neuropathy of impaired glucose regulation. Muscle & nerve\| PubMed ID: 19260066	2009
Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation. Biochimie\| PubMed ID: 19278624	2009
Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery. Growth factors (Chur, Switzerland)\| PubMed ID: 19294549	2009
Computational methods for predicting sites of functionally important dynamics. The journal of physical chemistry. B\| PubMed ID: 19378962	2009
Elevated triglycerides correlate with progression of diabetic neuropathy. Diabetes\| PubMed ID: 19411614	2009
Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Int... Circulation\| PubMed ID: 19470886	2009
Dyslipidemia-induced neuropathy in mice: the role of oxLDL/LOX-1. Diabetes\| PubMed ID: 19592619	2009
Patterning N-type and S-type neuroblastoma cells with Pluronic F108 and ECM proteins. Journal of biomedical materials research. Part A\| PubMed ID: 19609877	2010
SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 19638400	2009
Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration. Developmental neurobiology\| PubMed ID: 19672955	2009
Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes. Journal of neuropathology and experimental neurology\| PubMed ID: 19816194	2009
Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. Endocrinology\| PubMed ID: 19819959	2009
Mitochondrial DNA (mtDNA) Biogenesis: Visualization and Duel Incorporation of BrdU and EdU Into Newly Synthesized mtDNA In Vitro. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 19875847	2009
Hyperlipidemia: a new therapeutic target for diabetic neuropathy. Journal of the peripheral nervous system : JPNS\| PubMed ID: 20021567	2009
The management of diabetic neuropathy in CKD. American journal of kidney diseases : the official journal of the National Kidney Foundation\| PubMed ID: 20042258	2010
Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interve... Diabetes care\| PubMed ID: 20150297	2010
Accelerated neuritogenesis and maturation of primary spinal motor neurons in response to nanofibers. Developmental neurobiology\| PubMed ID: 20213755	2010
The pleotrophic effects of insulin-like growth factor-I on human spinal cord neural progenitor cells. Stem cells and development\| PubMed ID: 20406098	2010
DCCT and EDIC studies in type 1 diabetes: lessons for diabetic neuropathy regarding metabolic memory and natural history. Current diabetes reports\| PubMed ID: 20464532	2010
Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy. Acta neuropathologica\| PubMed ID: 20473509	2010
Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20479236	2010
p38 mediates mechanical allodynia in a mouse model of type 2 diabetes. Molecular pain\| PubMed ID: 20482876	2010
The role of MTMR14 in autophagy and in muscle disease. Autophagy\| PubMed ID: 20595810	2010
The effects of anesthesia on measures of nerve conduction velocity in male C57Bl6/J mice. Neuroscience letters\| PubMed ID: 20691755	2010
Vibration perception threshold as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: results from the DCCT/EDIC study. Diabetes care\| PubMed ID: 20833868	2010
How does diabetes accelerate Alzheimer disease pathology? Nature reviews. Neurology\| PubMed ID: 20842183	2010
Literature-based discovery of diabetes- and ROS-related targets. BMC medical genomics\| PubMed ID: 20979611	2010
Cervical multilevel intraspinal stem cell therapy: assessment of surgical risks in Gottingen minipigs. Spine\| PubMed ID: 21099736	2011
Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1. Proteins\| PubMed ID: 21104697	2011
Cortical neurons develop insulin resistance and blunted Akt signaling: a potential mechanism contributing to enhanced ischemic injury in diabetes. Antioxidants & redox signaling\| PubMed ID: 21194385	2011
Stem cell technology for the study and treatment of motor neuron diseases. Regenerative medicine\| PubMed ID: 21391854	2011
Evidence-based guideline: treatment of painful diabetic neuropathy--report of the American Association of Neuromuscular and Electrodiagnostic Medicine, the American Academy of Neurology, and... Muscle & nerve\| PubMed ID: 21484835	2011
Transcriptional profiling of diabetic neuropathy in the BKS db/db mouse: a model of type 2 diabetes. Diabetes\| PubMed ID: 21617178	2011
Optimization of immunosuppressive therapy for spinal grafting of human spinal stem cells in a rat model of ALS. Cell transplantation\| PubMed ID: 21669047	2011
Diabetic Polyneuropathies: Update on Research Definition, Diagnostic Criteria and Estimation of Severity. Diabetes/metabolism research and reviews\| PubMed ID: 21695763	2011
Comment: Career guidelines promote neurologist satisfaction. Neurology\| PubMed ID: 21795654	2011
Effect of mild hyperglycemia on autonomic function in obstructive sleep apnea. Clinical autonomic research : official journal of the Clinical Autonomic Research Society\| PubMed ID: 21796355	2012
Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons. Endocrinology\| PubMed ID: 21810948	2011
Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network. BMC immunology\| PubMed ID: 21871085	2011
Nerve growth factor/p38 signaling increases intraepidermal nerve fiber densities in painful neuropathy of type 2 diabetes. Neurobiology of disease\| PubMed ID: 21872660	2012
Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 21900648	2011
Stem cell technology for neurodegenerative diseases. Annals of neurology\| PubMed ID: 21905078	2011
Diabetic neuropathy: cellular mechanisms as therapeutic targets. Nature reviews. Neurology\| PubMed ID: 21912405	2011
The identification of gene expression profiles associated with progression of human diabetic neuropathy. Brain : a journal of neurology\| PubMed ID: 21926103	2011
The Evaluation of Distal Symmetric Polyneuropathy: A Physician Survey of Clinical Practice. Archives of neurology\| PubMed ID: 22083798	2011
Translational stem cell therapy for amyotrophic lateral sclerosis. Nature reviews. Neurology\| PubMed ID: 22158518	2011
Potential for promoting recurrent laryngeal nerve regeneration by remote delivery of viral gene therapy. The Laryngoscope\| PubMed ID: 22241608	2012
Insulin resistance in the nervous system. Trends in endocrinology and metabolism: TEM\| PubMed ID: 22245457	2012
Intraspinal transplantation of neurogenin-expressing stem cells generates spinal cord neural progenitors. Neurobiology of disease\| PubMed ID: 22245661	2012
A novel approach to study motor neurons from zebrafish embryos and larvae in culture. Journal of neuroscience methods\| PubMed ID: 22285259	2012
A new member of the multidisciplinary ALS team: The otolaryngologist. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases\| PubMed ID: 22292845	2012