Yaohe Wang

Center for Molecular Oncology, Queen Mary University of London

Affiliated withQueen Mary University of London Zhengzhou University Zhengzhou University

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 13	2016
Publication title Cited by 24	2018

Other Publications

Article	Year
Novel immunocompetent murine tumor models for the assessment of replication-competent oncolytic adenovirus efficacy. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 12946314	2003
E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models. Nature biotechnology\| PubMed ID: 14555956	2003
Quantitative imaging of Na/I symporter transgene expression using positron emission tomography in the living animal. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15006611	2004
An E1B-19 kDa gene deletion mutant adenovirus demonstrates tumor necrosis factor-enhanced cancer selectivity and enhanced oncolytic potency. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15194046	2004
Interleukin-1beta and tumour necrosis factor-alpha promote the transformation of human immortalised mesothelial cells by erionite. International journal of oncology\| PubMed ID: 15202003	2004
Noninvasive imaging of the transcriptional activities of human telomerase promoter fragments in mice. Cancer research\| PubMed ID: 15256462	2004
A novel assay to assess primary human cancer infectibility by replication-selective oncolytic adenoviruses. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15671566	2005
Virus-associated RNA I-deleted adenovirus, a potential oncolytic agent targeting EBV-associated tumors. Cancer research\| PubMed ID: 15735041	2005
Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin. Cancer research\| PubMed ID: 16424034	2006
Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy. International journal of cancer\| PubMed ID: 17311258	2007
Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963. The Journal of clinical investigation\| PubMed ID: 17965776	2007
Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus. PLoS medicine\| PubMed ID: 18162040	2007
Enhancing poxvirus oncolytic effects through increased spread and immune evasion. Cancer research\| PubMed ID: 18381410	2008
CEACAM6 attenuates adenovirus infection by antagonizing viral trafficking in cancer cells. The Journal of clinical investigation\| PubMed ID: 19411761	2009
Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer. Gene therapy\| PubMed ID: 19587709	2009
Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours. Gene therapy\| PubMed ID: 19890355	2010
Combination of anti-angiogenic therapy and virotherapy: arming oncolytic viruses with anti-angiogenic genes. Current opinion in molecular therapeutics\| PubMed ID: 20072943	2009
Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles. Viruses\| PubMed ID: 20543907	2010
PRSS3 promotes tumour growth and metastasis of human pancreatic cancer. Gut\| PubMed ID: 20947888	2010
Lister vaccine strain of vaccinia virus armed with the endostatin-angiostatin fusion gene: an oncolytic virus superior to dl1520 (ONYX-015) for human head and neck cancer. Human gene therapy\| PubMed ID: 21361787	2011
Modification of the early gene enhancer-promoter improves the oncolytic potency of adenovirus 11. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22086234	2012
Systemic delivery of oncolytic viruses: hopes and hurdles. Advances in virology\| PubMed ID: 22400027	2012
A novel therapeutic regimen to eradicate established solid tumors with an effective induction of tumor-specific immunity. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23091113	2012
Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway. Journal of virology\| PubMed ID: 23269798	2013
Update on oncolytic viral therapy - targeting angiogenesis. OncoTargets and therapy\| PubMed ID: 23940420	2013
STAT1 interaction with E3-14.7K in monocytes affects the efficacy of oncolytic adenovirus. Journal of virology\| PubMed ID: 24335311	2014
A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 25416195	2015
Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system. Journal of virology\| PubMed ID: 25741005	2015
A novel compound WISP3 mutation in a Chinese family with progressive pseudorheumatoid dysplasia. Gene\| PubMed ID: 25794430	2015
Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus without Compromising Anticancer Activity. Cancer research\| PubMed ID: 25977332	2015
New role of Interleukin-10 in enhancing the antitumor efficacy of oncolytic vaccinia virus for treatment of pancreatic cancer. Oncoimmunology\| PubMed ID: 26405610	2015
A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9. Molecular therapy. Methods & clinical development\| PubMed ID: 26417609	2015
Vaccinia virus, a promising new therapeutic agent for pancreatic cancer. Immunotherapy\| PubMed ID: 26595180	2015
CRISPR-Cas9 as a Powerful Tool for Efficient Creation of Oncolytic Viruses. Viruses\| PubMed ID: 26959050	2016
The efficacy of oncolytic adenovirus is mediated by T cell responses against virus and tumor in Syrian hamster model. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27435398	2016
Haploinsufficiency of Hand1 improves mice survival after acute myocardial infarction through preventing cardiac rupture. Biochemical and biophysical research communications\| PubMed ID: 27601324	2016
Genomic Variations in Pancreatic Cancer and Potential Opportunities for Development of New Approaches for Diagnosis and Treatment. International journal of molecular sciences\| PubMed ID: 28587243	2017
Oncolytic Viruses-Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer. Frontiers in oncology\| PubMed ID: 28944214	2017
Correction for Spurrell et al., "STAT1 Interaction with E3-14.7K in Monocytes Affects the Efficacy of Oncolytic Adenovirus". Journal of virology\| PubMed ID: 28956778	2017
Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent. Nature communications\| PubMed ID: 29123084	2017