Sijie Chen

Institutes of Brain Science, Fudan University

Affiliated withFudan University Karolinska Institutet Sichuan University

Research Area

Biography

Sijie Chen obtained her PhD from Hong Kong University of Science and Technology in 2013. She received the Endeavour fellowship and worked as an Endeavour Fellow in University of Melbourne and a visiting scientist in Walter and Eliza Hall Institute of Medical Research (WEHI) in 2015. Thereafter, she joined Karolinksa Institutet (KI) in Sweden as a postdoctoral fellow. Dr. Chen was recruited as an Assistant Professor at Ming Wai Lau Centre for Reparative Medicine, KI, Hong Kong in 2017. Her current research interests focus on the development of new luminescent materials and techniques for biological research.

JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 6	2017
Publication title Cited by 7	2019
Publication title	2026

Other Publications

Article	Year
Experimental studies and modeling on concentration polarization in forward osmosis. Water science and technology : a journal of the International Association on Water Pollution Research\| PubMed ID: 20489263	2010
Cytophilic fluorescent bioprobes for long-term cell tracking. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 21671445	2011
Fluorogenic Zn(II) and chromogenic Fe(II) sensors based on terpyridine-substituted tetraphenylethenes with aggregation-induced emission characteristics. ACS applied materials & interfaces\| PubMed ID: 21834577	2011
Monitoring and inhibition of insulin fibrillation by a small organic fluorogen with aggregation-induced emission characteristics. Journal of the American Chemical Society\| PubMed ID: 22191699	2012
Sequence analysis of the Bs-Ag1 gene of Baylisascaris schroederi from the giant panda and an evaluation of the efficacy of a recombinant Baylisascaris schroederi Bs-Ag1 antigen in mice. DNA and cell biology\| PubMed ID: 22339267	2012
Benzothiazolium-functionalized tetraphenylethene: an AIE luminogen with tunable solid-state emission. Chemical communications (Cambridge, England)\| PubMed ID: 22822484	2012
Synthesis, solvatochromism, aggregation-induced emission and cell imaging of tetraphenylethene-containing BODIPY derivatives with large Stokes shifts. Chemical communications (Cambridge, England)\| PubMed ID: 22957342	2012
A photostable AIE luminogen for specific mitochondrial imaging and tracking. Journal of the American Chemical Society\| PubMed ID: 23244346	2013
Fabrication of chitosan nanoparticles with aggregation-induced emission characteristics and their applications in long-term live cell imaging. Macromolecular rapid communications\| PubMed ID: 23401040	2013
Full-range intracellular pH sensing by an aggregation-induced emission-active two-channel ratiometric fluorogen. Journal of the American Chemical Society\| PubMed ID: 23506236	2013
Fabrication of fluorescent silica nanoparticles with aggregation-induced emission luminogens for cell imaging. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23546668	2013
Water-soluble tetraphenylethene derivatives as fluorescent "light-up" probes for nucleic acid detection and their applications in cell imaging. Chemistry, an Asian journal\| PubMed ID: 23596133	2013
Long-term fluorescent cellular tracing by the aggregates of AIE bioconjugates. Journal of the American Chemical Society\| PubMed ID: 23668387	2013
Thiol-reactive molecule with dual-emission-enhancement property for specific prestaining of cysteine containing proteins in SDS-PAGE. ACS applied materials & interfaces\| PubMed ID: 23721624	2013
Highly fluorescent and photostable probe for long-term bacterial viability assay based on aggregation-induced emission. Advanced healthcare materials\| PubMed ID: 23814037	2014
Potential of recombinant inorganic pyrophosphatase antigen as a new vaccine candidate against Baylisascaris schroederi in mice. Veterinary research\| PubMed ID: 24090087	2013
Ordered honeycomb structural interfaces for anticancer cells growth. Langmuir : the ACS journal of surfaces and colloids\| PubMed ID: 24219118	2013
Superior fluorescent probe for detection of cardiolipin. Analytical chemistry\| PubMed ID: 24372165	2014
A selective glutathione probe based on AIE fluorogen and its application in enzymatic activity assay. Scientific reports\| PubMed ID: 24603274	2014
A tetraphenylethene-based caged compound: synthesis, properties and applications. Chemical communications (Cambridge, England)\| PubMed ID: 24923580	2014
A dual functional AEE fluorogen as a mitochondrial-specific bioprobe and an effective photosensitizer for photodynamic therapy. Chemical communications (Cambridge, England)\| PubMed ID: 25302466	2014
Detection of oligomers and fibrils of α-synuclein by AIEgen with strong fluorescence. Chemical communications (Cambridge, England)\| PubMed ID: 25526628	2015
Mapping live cell viscosity with an aggregation-induced emission fluorogen by means of two-photon fluorescence lifetime imaging. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 25645956	2015
Light-enhanced bacterial killing and wash-free imaging based on AIE fluorogen. ACS applied materials & interfaces\| PubMed ID: 25789982	2015
Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test. Neuropharmacology\| PubMed ID: 25842247	2015
Real-time monitoring of the mitophagy process by a photostable fluorescent mitochondrion-specific bioprobe with AIE characteristics. Chemical communications (Cambridge, England)\| PubMed ID: 25939788	2015
A Luminogen with Aggregation-Induced Emission Characteristics for Wash-Free Bacterial Imaging, High-Throughput Antibiotics Screening and Bacterial Susceptibility Evaluation. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 26179636	2015
A red emitting mitochondria-targeted AIE probe as an indicator for membrane potential and mouse sperm activity. Chemical communications (Cambridge, England)\| PubMed ID: 26264419	2015
A Lysosome-Targeting AIEgen for Autophagy Visualization. Advanced healthcare materials\| PubMed ID: 26688031	2016
nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation. Molecular and cellular endocrinology\| PubMed ID: 27267667	2016
Rapid and accurate synthesis of TALE genes from synthetic oligonucleotides. BioTechniques\| PubMed ID: 27286807	2016
Novel super-resolution capable mitochondrial probe, MitoRed AIE, enables assessment of real-time molecular mitochondrial dynamics. Scientific reports\| PubMed ID: 27492961	2016
Reconfigurable Nonvolatile Logic Operations in Resistance Switching Crossbar Array for Large-Scale Circuits. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 27717010	2016
Performance Evaluation and Online Realization of Data-driven Normalization Methods Used in LC/MS based Untargeted Metabolomics Analysis. Scientific reports\| PubMed ID: 27958387	2016
AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications. Molecules (Basel, Switzerland)\| PubMed ID: 29443927	2018
Fluorogenic Detection and Characterization of Proteins by Aggregation-Induced Emission Methods. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 30601578	2019
Imaging Macrophage Phagocytosis Using AIE Luminogen-Labeled E. coli. Chemistry, an Asian journal\| PubMed ID: 30698362	2019
Clinical significance of LOXL4 expression and features of LOXL4-associated protein-protein interaction network in esophageal squamous cell carcinoma. Amino acids\| PubMed ID: 30900087	2019
A Small-Molecule AIE Chromosome Periphery Probe for Cytogenetic Studies. Angewandte Chemie (International ed. in English)\| PubMed ID: 32163217	2020
A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 34190409	2021
Nonocular Influencing Factors for Primary Glaucoma: An Umbrella Review of Meta-Analysis. Ophthalmic research\| PubMed ID: 34517373	2021
A near-infrared AIE fluorescent probe for myelin imaging: From sciatic nerve to the optically cleared brain tissue in 3D. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 34740969	2021
A New Strategy for High-Efficient Tandem Enrichment and Simultaneous Profiling of N-Glycopeptides and Phosphopeptides in Lung Cancer Tissue. Frontiers in molecular biosciences\| PubMed ID: 35685241	2022
Abnormal expression of TSG-6 disturbs extracellular matrix homeostasis in chondrocytes from endemic osteoarthritis. Frontiers in genetics\| PubMed ID: 36468025	2022
Cellular features of localized microenvironments in human meniscal degeneration: a single-cell transcriptomic study. eLife\| PubMed ID: 36548025	2022
Differential expression of cyclins CCNB1 and CCNG1 is involved in the chondrocyte damage of kashin-beck disease. Frontiers in genetics\| PubMed ID: 36588792	2022
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein. Signal transduction and targeted therapy\| PubMed ID: 38853183	2024
Changes in prostaglandin-associated periorbital syndrome: a self-controlled and prospective study. Cutaneous and ocular toxicology\| PubMed ID: 39620977	2025
Enhanced Conductivity in Conjugated Microporous Polymers via Integrating of Carbon Nanotubes for Ultrasensitive NO Chemiresistive Sensor. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 39696927	2025
Outcomes of laser peripheral iridotomy in subgroups of primary angle closure disease eyes according to swept-source optical coherence tomography parameters. Eye (London, England)\| PubMed ID: 40247057	2025
Global, regional, and national burdens of shoulder dislocation in adolescents and young adults, 1990-2021: A population-based study. Chinese medical journal\| PubMed ID: 40789669	2025
Cultural heritage of the Qin-Shu Ancient Road in Shaanxi: Spatial distribution characteristics and influencing factors. PloS one\| PubMed ID: 40924752	2025
Surgical Treatment Is Superior to Conservative Options in Preventing Recurrence of First-Time Anterior Shoulder Dislocation in Adolescents and Adults Under 40 Years of Age: A Systematic Revi... Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association\| PubMed ID: 40939903	2025
[Comparative study on accuracy of three imaging methods in diagnosis of subacromial impingement syndrome]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery\| PubMed ID: 41093794	2025