Xi Chen

Department of Chemistry, University of California-Davis

Affiliated withUniversity of California-Davis Baylor College of Medicine Chongqing Hospital of Traditional Chinese Medicine

Research Area

Biography

Dr. Chen received her Ph.D. in Molecular Cell & Developmental Biology from University of Texas at Austin. She was a postdoctoral fellow at Stanford University School of Medicine. Dr. Chen started her own independent research as a tenure track assistant professor at Johns Hopkins University in 2008 and is a full professor now. Dr. Chen’s laboratory investigates epigenetic regulation in various stem cell lineages during animal development, using model organisms Drosophila, C. elegans and mice.

JoVE Journal Publications

ArticleTotal : 8	Year
Publication title Cited by 35	2017
Publication title Cited by 15	2020
Publication title	2024
Publication title	2024
Publication title Cited by 2	2024

Other Publications

Article	Year
The histone methyltransferase Smyd2 is a negative regulator of macrophage activation by suppressing interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) production. The Journal of biological chemistry\| PubMed ID: 25583990	2015
Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes. Nature genetics\| PubMed ID: 26301496	2015
EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer. The EMBO journal\| PubMed ID: 26492917	2015
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26862168	2016
Outcomes of cataract surgery with residents as primary surgeons in the Veterans Affairs Healthcare System. Journal of cataract and refractive surgery\| PubMed ID: 27063517	2016
Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity. Gastroenterology\| PubMed ID: 28625833	2017
SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation. Diabetes\| PubMed ID: 28851713	2018
Genome-wide identification and differential analysis of translational initiation. Nature communications\| PubMed ID: 29170441	2017
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. The Journal of clinical investigation\| PubMed ID: 29480818	2018
Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy. Cardiovascular research\| PubMed ID: 29878150	2019
miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. Diabetes\| PubMed ID: 30002134	2018
Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer. Cell reports\| PubMed ID: 30089255	2018
miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem cells (Dayton, Ohio)\| PubMed ID: 30267595	2018
Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution. Antioxidants & redox signaling\| PubMed ID: 30358421	2019
Is a Tumor Suppressor Gene in Colorectal Cancer. Molecular cancer research : MCR\| PubMed ID: 30606770	2019
Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells. Nature cell biology\| PubMed ID: 30778220	2019
The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc. Nature immunology\| PubMed ID: 31086333	2019
PTPN3 acts as a tumor suppressor and boosts TGF-β signaling independent of its phosphatase activity. The EMBO journal\| PubMed ID: 31304624	2019
Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines. Genome medicine\| PubMed ID: 31446897	2019
Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. Cell\| PubMed ID: 31675502	2019
The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic acids research\| PubMed ID: 31863590	2020
12-h clock regulation of genetic information flow by XBP1s. PLoS biology\| PubMed ID: 31935211	2020
Proteogenomic Characterization of Endometrial Carcinoma. Cell\| PubMed ID: 32059776	2020
Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer. Cancer cell\| PubMed ID: 32142667	2020
Psoriasis Vulgaris of Blood Heat Syndrome in Plasma Based on Widely Targeted Techniques. Journal of healthcare engineering\| PubMed ID: 35463691	2022
Traditional Chinese medicine auricular point acupressure for the relief of pain, fatigue, and gastrointestinal adverse reactions after the injection of novel coronavirus-19 vaccines: a struc... Trials\| PubMed ID: 33632286	2021
Auricular acupressure for adverse events following immunization related to COVID-19 vaccine injection: study protocol for a multicenter, three-arm, blinded randomized controlled trial. Trials\| PubMed ID: 34838110	2021
Continuous theta burst stimulation over left and right supramarginal gyri demonstrates their involvement in auditory feedback control of vocal production. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 35174862	2022
MRI Fat-Saturated T2-Weighted Radiomics Model for Identifying the Ki-67 Index of Soft Tissue Sarcomas. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 36326136	2023
Auricular acupressure for adverse events following immunization after COVID-19 vaccine injection: A multicentre, blinded, randomized controlled trial. Complementary therapies in medicine\| PubMed ID: 36372315	2022
The relationship between sublingual immunotherapy for allergic rhinitis and the risk of symptoms in patients with COVID-19 infection. Human vaccines & immunotherapeutics\| PubMed ID: 37530139	2023
Intratumoral and peritumoral MRI-based radiomics prediction of histopathological grade in soft tissue sarcomas: a two-center study. Cancer imaging : the official publication of the International Cancer Imaging Society\| PubMed ID: 37885031	2023
Prenatal heavy metal exposure and pediatric asthma, allergic rhinitis, atopic dermatitis: a systematic review and meta-analysis. Expert review of clinical immunology\| PubMed ID: 39109589	2024
Intranasal insulin for the treatment of olfactory dysfunction: a protocol for a systematic review and meta-analysis. BMJ open\| PubMed ID: 39532357	2024
Efficacy and safety of retention enema with traditional Chinese medicine for ulcerative colitis: A meta-analysis of randomized controlled trials. Complementary therapies in clinical practice\| PubMed ID: 33276227	2021