Mayra Furlan-Magaril

Nuclear Dynamics Programme, Babraham Research Campus

Affiliated withBabraham Research Campus Universidad Nacional Autónoma de México

Research Area

Biography

Mayra is a molecular biologist specialized in epigenetics and genome architecture dedicated to understand how genome 3D conformation contributes to gene expression control and genomic stability.

Mayra studied her PhD at the UNAM in Mexico City investigating the function of a CTCF dependent insulator within the alfa-globin gene domain. As a postdoc Mayra became a fellow at the Babraham Institute in Cambridge, UK and continued to characterize structural components of the genome and their function.

Currently Mayra is a junior group leader at the Cellular Physiology Institute at the UNAM. Her research group is investigating the function of genome structure in gene expression control.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 115	2018
Publication title	2021

Other Publications

Article	Year
Neural stem cells in development and regenerative medicine. Archives of medical research\| PubMed ID: 14734098	2003
Globin genes transcriptional switching, chromatin structure and linked lessons to epigenetics in cancer: a comparative overview. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology\| PubMed ID: 17188536	2007
Protection against telomeric position effects by the chicken cHS4 beta-globin insulator. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17715059	2007
Sequential chromatin immunoprecipitation protocol: ChIP-reChIP. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19378171	2009
An insulator embedded in the chicken α-globin locus regulates chromatin domain configuration and differential gene expression. Nucleic acids research\| PubMed ID: 20813760	2011
The Krüppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development. Molecular and cellular endocrinology\| PubMed ID: 21182892	2011
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes. Nature structural & molecular biology\| PubMed ID: 21602820	2011
Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter. BMC cancer\| PubMed ID: 21663659	2011
The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements. Genome research\| PubMed ID: 25752748	2015
Individual and Sequential Chromatin Immunoprecipitation Protocols. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 26404152	2015
Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature genetics\| PubMed ID: 28805829	2017
Shaping Up the Embryo: The Role of Genome 3D Organization. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29564771	2018
RNA proximity sequencing reveals the spatial organization of the transcriptome in the nucleus. Nature biotechnology\| PubMed ID: 31267103	2019
RNA Interactions Are Essential for CTCF-Mediated Genome Organization. Molecular cell\| PubMed ID: 31522988	2019
In situ dissection of domain boundaries affect genome topology and gene transcription in Drosophila. Nature communications\| PubMed ID: 32060283	2020
The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle. Genome biology\| PubMed ID: 34099014	2021
Editorial: Chromatin Spatial Configuration and Function in Metazoans. Frontiers in genetics\| PubMed ID: 34456981	2021