Stephen L. Archer

Department of Medicine, Queen's University

Research Area

Biography

Stephen L. Archer has not added Biography.
If you are Stephen L. Archer and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 5	2018
Publication title Cited by 11	2020

Other Publications

Article	Year
Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circulation research\| PubMed ID: 23334860	2013
PGC1α-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 23449689	2013
The role of redox signaling in epigenetics and cardiovascular disease. Antioxidants & redox signaling\| PubMed ID: 23480168	2013
Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension. Pulmonary circulation\| PubMed ID: 23662191	2013
Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 23794090	2013
Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus. The Canadian journal of cardiology\| PubMed ID: 23916739	2013
Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24076965	2014
SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress. Molecular and cellular biology\| PubMed ID: 24344202	2014
Relevant issues in the pathology and pathobiology of pulmonary hypertension. Journal of the American College of Cardiology\| PubMed ID: 24355640	2013
Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 24906456	2014
The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circulation research\| PubMed ID: 24951766	2014
Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension. Circulation\| PubMed ID: 25361553	2015
Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model. Critical care medicine\| PubMed ID: 25599491	2015
Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 25669447	2015
Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Clinical pharmacology and therapeutics\| PubMed ID: 25670386	2015
Mitochondrial dynamics in pulmonary arterial hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 25672499	2015
Right ventricular adaptation and failure in pulmonary arterial hypertension. The Canadian journal of cardiology\| PubMed ID: 25840092	2015
Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmo... Circulation\| PubMed ID: 25964279	2015
A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus. Pflugers Archiv : European journal of physiology\| PubMed ID: 26395471	2016
Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection. Brain : a journal of neurology\| PubMed ID: 26408653	2015
Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 26926454	2016
Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes. Cardiovascular research\| PubMed ID: 27216865	2016
Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications. Advances in experimental medicine and biology\| PubMed ID: 27343087	2016
Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine. Chest\| PubMed ID: 27645688	2017
MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype. American journal of respiratory and critical care medicine\| PubMed ID: 27648837	2017
The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease. Clinical science (London, England : 1979)\| PubMed ID: 27660309	2016
Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 27689707	2016
Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension. Pulmonary circulation\| PubMed ID: 28090301	2016
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 28265681	2017
Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis\| PubMed ID: 28362648	2017
Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension. Journal of the American Heart Association\| PubMed ID: 28566298	2017
Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment. Pulmonary circulation\| PubMed ID: 28680587	2017
Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 28893516	2018
Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 29158355	2018
Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension. Circulation\| PubMed ID: 29255124	2017
Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension. American journal of respiratory and critical care medicine\| PubMed ID: 29360393	2018
Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic a... Circulation\| PubMed ID: 29431643	2018
Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada. Circulation. Cardiovascular quality and outcomes\| PubMed ID: 29444925	2018
Pulmonary arterial hypertension: pathogenesis and clinical management. BMJ (Clinical research ed.)\| PubMed ID: 29540357	2018
Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research. Circulation research\| PubMed ID: 29599278	2018
A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 29877097	2018
Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension. Frontiers in physiology\| PubMed ID: 30042687	2018
A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension. The Canadian journal of cardiology\| PubMed ID: 30170664	2018
Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnor... International journal of molecular sciences\| PubMed ID: 30213070	2018
Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 30391191	2018