A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Medicine,Queen’s University, 2Department of Biomedical and Molecular Sciences,Queen’s University, 3Department of Cell Physiology,The Jikei University School of Medicine, 4Department of Pediatrics,The Jikei University School of Medicine, 5Department of Cardiovascular Surgery,The Jikei University School of Medicine
Chapters
- 00:00Title
- 01:20Pre-operative Preparation
- 02:02Anaesthesia and Endotracheal Intubation
- 03:11Preparation of the Surgical Site
- 03:38Left Atrial Stenosis Surgery
- 06:11Confirm the Success of Left Atrial Stenosis with Echocardiography
- 06:21Representative Results
- 07:43Conclusion
Left atrial stenosis (LAS) is a novel surgical technique used for studying group 2 pulmonary hypertension (PH) and mechanisms underlying pulmonary venous arterialization. Here, we present a protocol to constrict the left atrium using a titanium clip to cause pulmonary venous arterialization and moderate PH in a rat.
