Saad S. Kenderian

Department of Immunology, Mayo Clinic

Affiliated withMayo Clinic Mayo Clinic, Rochester Mayo Clinic Graduate School of Biomedical Sciences

Research Area

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JoVE Journal Publications

ArticleTotal : 5	Year
Publication title Cited by 34	2019
Publication title Cited by 8	2022
Publication title Cited by 4	2023
Publication title	2025
Publication title	2025

Other Publications

Article	Year
Bone marrow findings of the newly described TEMPI syndrome: when erythrocytosis and plasma cell dyscrasia coexist. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 25216227	2015
The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 26819453	2016
The Microbiome and Immune Regulation After Transplantation. Transplantation\| PubMed ID: 27517729	2017
Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies. The Journal of clinical investigation\| PubMed ID: 27571406	2016
Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 27638367	2017
Pharmacovigilance during ibrutinib therapy for chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) in routine clinical practice. Leukemia & lymphoma\| PubMed ID: 27820970	2017
Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia. Blood\| PubMed ID: 28246194	2017
Overcoming the Immunosuppressive Tumor Microenvironment of Hodgkin Lymphoma Using Chimeric Antigen Receptor T Cells. Cancer discovery\| PubMed ID: 28576927	2017
Generating and Expanding Autologous Chimeric Antigen Receptor T Cells from Patients with Acute Myeloid Leukemia. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28735493	2017
Liver dysfunction in chronic lymphocytic leukemia: Prevalence, outcomes, and pathological findings. American journal of hematology\| PubMed ID: 28940587	2017
Next-Generation Chimeric Antigen Receptor T-Cell Therapy: Going off the Shelf. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 29143249	2017
Outcomes of a large cohort of individuals with clinically ascertained high-count monoclonal B-cell lymphocytosis. Haematologica\| PubMed ID: 29419435	2018
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia. Cell\| PubMed ID: 29856956	2018
Autoimmune cytopenias in patients with chronic lymphocytic leukaemia treated with ibrutinib in routine clinical practice at an academic medical centre. British journal of haematology\| PubMed ID: 30117139	2018
Chimeric Antigen Receptor T-Cells: Successful Translation of the First Cell and Gene Therapy From Bench to Bedside. Clinical and translational science\| PubMed ID: 30242965	2018
GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood\| PubMed ID: 30463995	2019
IGH translocations in chronic lymphocytic leukemia: Clinicopathologic features and clinical outcomes. American journal of hematology\| PubMed ID: 30575108	2019
CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies. The AAPS journal\| PubMed ID: 30963322	2019
Rapid disease progression following discontinuation of ibrutinib in patients with chronic lymphocytic leukemia treated in routine clinical practice. Leukemia & lymphoma\| PubMed ID: 31014142	2019
Management of cytokine release syndrome: an update on emerging antigen-specific T cell engaging immunotherapies. Immunotherapy\| PubMed ID: 31161844	2019
Clinical characteristics and outcomes of Richter transformation: Experience of 204 patients from a single center. Haematologica\| PubMed ID: 31197071	2019
Myeloid cell and cytokine interactions with chimeric antigen receptor-T-cell therapy: implication for future therapies. Current opinion in hematology\| PubMed ID: 31764168	2020
Addition of venetoclax at time of progression in ibrutinib-treated patients with chronic lymphocytic leukemia: Combination therapy to prevent ibrutinib flare. American journal of hematology\| PubMed ID: 31788844	2020
Baseline immune dysregulation in autologous stem cell transplant recipients is associated with a 'graft versus host'-like syndrome and poor outcomes. Bone marrow transplantation\| PubMed ID: 32161319	2020
The impact of dose modification and temporary interruption of ibrutinib on outcomes of chronic lymphocytic leukemia patients in routine clinical practice. Cancer medicine\| PubMed ID: 32187452	2020
A Graduate-Level Interdisciplinary Curriculum in CAR-T Cell Therapy. Mayo Clinic proceedings. Innovations, quality & outcomes\| PubMed ID: 32280931	2020
CAR T-cell therapy for the management of refractory/relapsed high-grade B-cell lymphoma: a practical overview. Bone marrow transplantation\| PubMed ID: 32305998	2020
Human chimeric antigen receptor macrophages for cancer immunotherapy. Nature biotechnology\| PubMed ID: 32361713	2020
Incidence and risk of tumor lysis syndrome in patients with relapsed chronic lymphocytic leukemia (CLL) treated with venetoclax in routine clinical practice. Leukemia & lymphoma\| PubMed ID: 32449401	2020
Atrial fibrillation in patients with chronic lymphocytic leukemia (CLL) treated with ibrutinib: risk prediction, management, and clinical outcomes. Annals of hematology\| PubMed ID: 32488603	2021
Characteristics of late transplant-associated thrombotic microangiopathy in patients who underwent allogeneic hematopoietic stem cell transplantation. American journal of hematology\| PubMed ID: 32618000	2020
CRISPR Taking the Front Seat in Immunotherapy. Journal of cellular immunology\| PubMed ID: 32776020	2020
Disease Flare During Temporary Interruption of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia. The oncologist\| PubMed ID: 32886416	2020
Neurotoxicity and Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy: Insights Into Mechanisms and Novel Therapies. Frontiers in immunology\| PubMed ID: 32983132	2020
A Concise Review of Neurologic Complications Associated with Chimeric Antigen Receptor T-cell Immunotherapy. Neurologic clinics\| PubMed ID: 33040871	2020
Anti-CD19 chimeric antigen receptor T-cell therapy in acute lymphocytic leukaemia: a systematic review and meta-analysis. The Lancet. Haematology\| PubMed ID: 33091355	2020
The role of 18F-FDG-PET in detecting Richter's transformation of chronic lymphocytic leukemia in patients receiving therapy with a B-cell receptor inhibitor. Haematologica\| PubMed ID: 33131260	2020
GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia: A Case-Cohort Study. Mayo Clinic proceedings\| PubMed ID: 33153629	2020
Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 33388419	2021
CART Cell Toxicities: New Insight into Mechanisms and Management. Clinical hematology international\| PubMed ID: 33409484	2020
CRISPR Takes the Front Seat in CART-Cell Development. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 33638865	2021
Venetoclax treatment of patients with relapsed T-cell prolymphocytic leukemia. Blood cancer journal\| PubMed ID: 33654067	2021
In Reply - Clinical Benefit of Lenzilumab in Cases of Coronavirus Disease 2019. Mayo Clinic proceedings\| PubMed ID: 33673930	2021
Resistance to CART cell therapy: lessons learned from the treatment of hematological malignancies. Leukemia & lymphoma\| PubMed ID: 33682608	2021
The prognostic significance of del6q23 in chronic lymphocytic leukemia. American journal of hematology\| PubMed ID: 33749852	2021
CART cell imaging: Paving the way for success in CART cell therapy. Molecular therapy oncolytics\| PubMed ID: 33816781	2021
The CLL International Prognostic Index predicts outcomes in monoclonal B-cell lymphocytosis and Rai 0 CLL. Blood\| PubMed ID: 33876228	2021
Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome. Blood cancer journal\| PubMed ID: 33972504	2021
Development of a Clinically Relevant Reporter for Chimeric Antigen Receptor T-cell Expansion, Trafficking, and Toxicity. Cancer immunology research\| PubMed ID: 34244299	2021
Cause of death in patients with newly diagnosed chronic lymphocytic leukemia (CLL) stratified by the CLL-International Prognostic Index. Blood cancer journal\| PubMed ID: 34354039	2021
Humoral and cellular immune responses to recombinant herpes zoster vaccine in patients with chronic lymphocytic leukemia and monoclonal B cell lymphocytosis. American journal of hematology\| PubMed ID: 34699616	2022
Differential transcriptomic profiling in ibrutinib-naïve versus ibrutinib-resistant Richter syndrome. Hematological oncology\| PubMed ID: 34806797	2021
Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma. Blood\| PubMed ID: 35090171	2022
Chronic lymphocytic leukemia (CLL) with Reed-Sternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter? Blood cancer journal\| PubMed ID: 35091549	2022
Challenges of CAR T-cell Therapy in CLL: Lessons Learned. Experimental hematology\| PubMed ID: 35150777	2022
GM-CSF disruption in CART cells modulates T cell activation and enhances CART cell anti-tumor activity. Leukemia\| PubMed ID: 35440691	2022
CAR-T Cell Therapy: the Efficacy and Toxicity Balance. Current hematologic malignancy reports\| PubMed ID: 36763238	2023
Chimeric antigen receptor T-cell therapy to target hematologic malignancies. Cancer research\| PubMed ID: 25371415	2014
Large B-cell transformation in nodular lymphocyte-predominant Hodgkin lymphoma: 40-year experience from a single institution. Blood\| PubMed ID: 26837698	2016
CAR T cell therapy and the tumor microenvironment: Current challenges and opportunities. Molecular therapy oncolytics\| PubMed ID: 35434273	2022
Serum B-Cell maturation antigen is an independent prognostic marker in previously untreated chronic lymphocytic leukemia. Experimental hematology\| PubMed ID: 35525334	2022
Role of CD19 Chimeric Antigen Receptor T Cells in Second-Line Large B Cell Lymphoma: Lessons from Phase 3 Trials. An Expert Panel Opinion from the American Society for Transplantation and Ce... Transplantation and cellular therapy\| PubMed ID: 35768052	2022
Combined ibrutinib and venetoclax for treatment of patients with ibrutinib-resistant or double-refractory chronic lymphocytic leukaemia. British journal of haematology\| PubMed ID: 35841338	2022
Therapy-related myeloid neoplasms following chimeric antigen receptor T-cell therapy for Non-Hodgkin Lymphoma. Blood cancer journal\| PubMed ID: 35882844	2022
Clinical outcomes in patients with chronic lymphocytic leukemia with disease progression on ibrutinib. Blood cancer journal\| PubMed ID: 36050317	2022
Lisocabtagene maraleucel in chronic lymphocytic leukaemia and small lymphocytic lymphoma (TRANSCEND CLL 004): a multicentre, open-label, single-arm, phase 1-2 study. Lancet (London, England)\| PubMed ID: 37295445	2023
AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells. Cancer immunology research\| PubMed ID: 37378662	2023
Safety of radiotherapy for second primary malignancies in patients with chronic lymphocytic leukemia receiving concurrent novel agent treatment. American journal of hematology\| PubMed ID: 37614209	2023
Who wins the combat, CAR or TCR? Leukemia\| PubMed ID: 37626090	2023
CD19 occupancy with tafasitamab increases therapeutic index of CART19 cell therapy and diminishes severity of CRS. Blood\| PubMed ID: 37879074	2024
Thyroid-stimulating hormone receptor (TSHR) as a target for imaging differentiated thyroid cancer. Surgery\| PubMed ID: 37919223	2024
Real-world associations of cytokine release syndrome and neurotoxicity with efficacy in patients receiving anti-CD-19 chimeric antigen receptor T-cell therapy for large B-cell lymphoma: the ... Leukemia & lymphoma\| PubMed ID: 38031734	2024
Features and Factors Associated With Myeloid Neoplasms After Chimeric Antigen Receptor T-Cell Therapy. JAMA oncology\| PubMed ID: 38386311	2024
A multicenter study of venetoclax-based treatment for patients with Richter transformation of chronic lymphocytic leukemia. Blood advances\| PubMed ID: 38537065	2024
Mesenchymal stromal cells with chimaeric antigen receptors for enhanced immunosuppression. Nature biomedical engineering\| PubMed ID: 38561490	2024
Artificial Intelligence Electrocardiography to Predict Atrial Fibrillation in Patients With Chronic Lymphocytic Leukemia. JACC. CardioOncology\| PubMed ID: 38774001	2024
Clonal dynamics of Richter transformation in chronic lymphocytic leukemia. Hematological oncology\| PubMed ID: 38852069	2024
PET Imaging of Differentiated Thyroid Cancer with TSHR-Targeted [Zr]Zr-TR1402. Molecular pharmaceutics\| PubMed ID: 38976794	2024
Chimeric antigen receptor T-cell therapy associated hemophagocytic lymphohistiocytosis syndrome: clinical presentation, outcomes, and management. Blood cancer journal\| PubMed ID: 39134524	2024
IL-4 drives exhaustion of CD8 CART cells. Nature communications\| PubMed ID: 39266501	2024
Bioengineering MSCs for untapped therapeutic potential. Immunotherapy\| PubMed ID: 39268677	2024
Incidence, risk factors, and outcomes of patients with monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia who develop venous thromboembolism. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 39343103	2025
Incidence of Richter transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma in the targeted therapy era. Leukemia\| PubMed ID: 39658628	2024
Chronic Lymphocytic Leukemia Infiltrating in the Brain. Cureus\| PubMed ID: 39712843	2024