Florian W. R. Vondran

Regenerative Medicine and Experimental Surgery, Hannover medical school

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 2	2022
Publication title	2020

Other Publications

Article	Year
Association of high anti-donor alloreactivity and low frequency of FoxP3-expressing cells prior to kidney transplantation with acute graft rejection. Clinical transplantation\| PubMed ID: 21070367	2011
Incidence and outcome of abdominal surgical interventions following lung transplantation--a single center experience. Langenbeck's archives of surgery\| PubMed ID: 21400068	2011
Decreased frequency of peripheral CD4(+) CD161(+) Th(17) -precursor cells in kidney transplant recipients on long-term therapy with Belatacept. Transplant international : official journal of the European Society for Organ Transplantation\| PubMed ID: 22348376	2012
Autophagy inhibition due to thymidine analogues as novel mechanism leading to hepatocyte dysfunction and lipid accumulation. AIDS (London, England)\| PubMed ID: 22914580	2012
Exchange of cytosolic content between T cells and tumor cells activates CD4 T cells and impedes cancer growth. PloS one\| PubMed ID: 24205259	2013
An extended ΔCT-method facilitating normalisation with multiple reference genes suited for quantitative RT-PCR analyses of human hepatocyte-like cells. PloS one\| PubMed ID: 24658132	2014
The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry. The Journal of antimicrobial chemotherapy\| PubMed ID: 24710028	2014
Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells. PloS one\| PubMed ID: 24816744	2014
Pre-transplant immune state defined by serum markers and alloreactivity predicts acute rejection after living donor kidney transplantation. Clinical transplantation\| PubMed ID: 24931031	2014
Helicobacter hepaticus induces an inflammatory response in primary human hepatocytes. PloS one\| PubMed ID: 24932686	2014
Explanted diseased livers - a possible source of metabolic competent primary human hepatocytes. PloS one\| PubMed ID: 24999631	2014
Species-specific regulation of fibrinogen synthesis with implications for porcine hepatocyte xenotransplantation. Xenotransplantation\| PubMed ID: 25175927	2014
Risk factors for short- and long-term mortality in liver transplant recipients with MELD score ≥30. Annals of transplantation\| PubMed ID: 25630462	2015
Modulation of HCV reinfection after orthotopic liver transplantation by fibroblast growth factor-2 and other non-interferon mediators. Gut\| PubMed ID: 25800783	2016
Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation. Hepatology (Baltimore, Md.)\| PubMed ID: 25999047	2015
Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released Viruses. PloS one\| PubMed ID: 26226615	2015
Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology (Baltimore, Md.)\| PubMed ID: 26248546	2016
Prediction of survival and tumor recurrence in patients undergoing surgery for pancreatic neuroendocrine neoplasms. Journal of surgical oncology\| PubMed ID: 26709239	2016
Immunological aspects of liver cell transplantation. World journal of transplantation\| PubMed ID: 27011904	2016
ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production. PLoS pathogens\| PubMed ID: 27124600	2016
Monitoring of liver function in a 73-year old patient undergoing 'Associating Liver Partition and Portal vein ligation for Staged hepatectomy': case report applying the novel liver maximum f... Patient safety in surgery\| PubMed ID: 27293483	2016
Inactivation of HCV and HIV by microwave: a novel approach for prevention of virus transmission among people who inject drugs. Scientific reports\| PubMed ID: 27857152	2016
Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture. Nature microbiology\| PubMed ID: 27991882	2016
Sodium taurocholate cotransporting polypeptide is the limiting host factor of hepatitis B virus infection in macaque and pig hepatocytes. Hepatology (Baltimore, Md.)\| PubMed ID: 28195359	2017
Scavenger receptor class B member 1 (SCARB1) variants modulate hepatitis C virus replication cycle and viral load. Journal of hepatology\| PubMed ID: 28363797	2017
Associating Liver Partition and Portal vein ligation for Staged hepatectomy after pre-operative chemotherapy. ANZ journal of surgery\| PubMed ID: 28419692	2018
Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity. Journal of hepatology\| PubMed ID: 28438690	2017
Pentagalloylglucose, a highly bioavailable polyphenolic compound present in Cortex moutan, efficiently blocks hepatitis C virus entry. Antiviral research\| PubMed ID: 28923507	2017
Early Tracheostomy Reduces Time of Mechanical Ventilation in Respiratory High-Risk Patients After Liver Transplant. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation\| PubMed ID: 29025380	2018
Myeloid Dendritic Cells Repress Human Cytomegalovirus Gene Expression and Spread by Releasing Interferon-Unrelated Soluble Antiviral Factors. Journal of virology\| PubMed ID: 29046460	2018
Hepatocyte-induced CD4 T cell alloresponse is associated with major histocompatibility complex class II up-regulation on hepatocytes and suppressible by regulatory T cells. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 29365365	2018
Hepatitis E virus replication and interferon responses in human placental cells. Hepatology communications\| PubMed ID: 29404525	2018
Hepatitis B virus DNA integration occurs early in the viral life cycle in an infection model via NTCP-dependent uptake of enveloped virus particles. Journal of virology\| PubMed ID: 29437961	2018
Modified ante situm liver resection without use of cold perfusion nor veno-venous bypass for treatment of hepatic lesions infiltrating the hepatocaval confluence. Langenbeck's archives of surgery\| PubMed ID: 29470630	2018
Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes. Journal of hepatology\| PubMed ID: 29524530	2018
Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes. Gastroenterology\| PubMed ID: 29535029	2018
Preoperative Recipient Parameters Allow Early Estimation of Postoperative Outcome and Intraoperative Transfusion Requirements in Liver Transplantation. Progress in transplantation (Aliso Viejo, Calif.)\| PubMed ID: 29558874	2018
Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice. PLoS pathogens\| PubMed ID: 30075026	2018
Relevant prognostic factors influencing outcome of patients after surgical resection of distal cholangiocarcinoma. BMC surgery\| PubMed ID: 30103720	2018
T5 exonuclease hydrolysis of Hepatitis B Virus replicative intermediates allows reliable quantification and fast drug efficacy testing of covalently closed circular DNA by PCR. Journal of virology\| PubMed ID: 30232183	2018
Use of Rotational Thromboelastometry in Liver Transplantation Is Associated With Reduced Transfusion Requirements. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation\| PubMed ID: 30295585	2019
Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis. Journal of hepatology\| PubMed ID: 30582979	2019
Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity. Journal of cellular and molecular medicine\| PubMed ID: 31180181	2019
Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver. Cells\| PubMed ID: 31216713	2019
Response to "Critical appraisal of the modified ante situm liver resection-is the original method the better choice?" Langenbeck's archives of surgery\| PubMed ID: 31256253	2019
Alloresponses of Mixed Lymphocyte Hepatocyte Culture to Immunosuppressive Drugs as an In-Vitro Model of Hepatocyte Transplantation. Annals of transplantation\| PubMed ID: 31406101	2019
Recipient natural killer cells alter the course of rejection of allogeneic heart grafts in rats. PloS one\| PubMed ID: 31437165	2019
A New Role for Capsid Assembly Modulators To Target Mature Hepatitis B Virus Capsids and Prevent Virus Infection. Antimicrobial agents and chemotherapy\| PubMed ID: 31658963	2019
Robust hepatitis E virus infection and transcriptional response in human hepatocytes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31896581	2020
Extended hepatic metastasectomy for renal cell carcinoma-new aspects in times of targeted therapy: a single-center experience over three decades. Langenbeck's archives of surgery\| PubMed ID: 31938833	2020
Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus. Gut\| PubMed ID: 32114504	2020
Long-term Functional Maintenance of Exteriorized Portal Venous Catheters in a Porcine Animal Model. The Journal of surgical research\| PubMed ID: 32163793	2020
C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle. Journal of hepatology\| PubMed ID: 32294532	2020
The importance of MHC class II in allogeneic bone marrow transplantation and chimerism-based solid organ tolerance in a rat model. PloS one\| PubMed ID: 32442182	2020
Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes. Viruses\| PubMed ID: 32485908	2020
The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly. PLoS pathogens\| PubMed ID: 32542055	2020
Therapeutic plasma exchange in acute on chronic liver failure. Journal of clinical apheresis\| PubMed ID: 32583446	2020
Abdominal Surgery in Patients with Ventricular Assist Devices: a Single-Center Report. ASAIO journal (American Society for Artificial Internal Organs : 1992)\| PubMed ID: 32740349	2020
Preoperative leukocytosis and the resection severity index are independent risk factors for survival in patients with intrahepatic cholangiocarcinoma. Langenbeck's archives of surgery\| PubMed ID: 32815017	2020
Surgical complications in pediatric kidney transplantation-Incidence, risk factors, and effects on graft survival: A retrospective single-center study. Pediatric transplantation\| PubMed ID: 33053269	2021
Longitudinal imaging and femtosecond laser manipulation of the liver: How to generate and trace single-cell-resolved micro-damage in vivo. PloS one\| PubMed ID: 33057345	2020
Liver-expressed and limit hepatitis C virus cross-species transmission to mice. Science advances\| PubMed ID: 33148654	2020
Diaphragmatic Hernia following Pediatric Liver Transplantation: An Underappreciated Complication Prone to Recur. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie\| PubMed ID: 33186999	2021
MicroRNA-125b-5p Regulates Hepatocyte Proliferation During the Termination Phase of Liver Regeneration. Hepatology communications\| PubMed ID: 33305155	2020
Distinct Immune Imprints of Post-Liver Transplantation Hepatitis C Persist Despite Viral Clearance. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 33641215	2021
Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements. Journal of virology\| PubMed ID: 33658347	2021
Direct conversion of porcine primary fibroblasts into hepatocyte-like cells. Scientific reports\| PubMed ID: 33927320	2021
Liver-first strategy for a combined lung and liver transplant in patients with cystic fibrosis. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 33956976	2021
Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity. Cells\| PubMed ID: 34209751	2021
BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment. Cell death & disease\| PubMed ID: 34312366	2021
Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model. Journal of hepatology\| PubMed ID: 34453962	2021
Outcome and safety of a surveillance biopsy guided personalized immunosuppression program after liver transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 34455702	2022
Proposal of a New Definition of "Very Early" Intrahepatic Cholangiocarcinoma-A Retrospective Single-Center Analysis. Journal of clinical medicine\| PubMed ID: 34575181	2021
Characterization of RNA Sensing Pathways in Hepatoma Cell Lines and Primary Human Hepatocytes. Cells\| PubMed ID: 34831243	2021
Surgical Procedures in Patients Awaiting Liver Transplantation: Complications and Impact on the Liver Function. Journal of clinical and experimental hepatology\| PubMed ID: 35068787	2022
Improved alpharetrovirus-based Gag.MS2 particles for efficient and transient delivery of CRISPR-Cas9 into target cells. Molecular therapy. Nucleic acids\| PubMed ID: 35141043	2022
Antibiotic-Resistant Bacteria Colonizing the Bile Duct Are Associated with Increased Morbidity and Mortality after Resection of Extrahepatic Cholangiocarcinoma. Surgical infections\| PubMed ID: 35172114	2022
Cold Ischemia Time and Graft Fibrosis Are Associated with Autoantibodies after Pediatric Liver Transplantation: A Retrospective Cohort Study of the European Reference Network . Children (Basel, Switzerland)\| PubMed ID: 35204995	2022
Liver Transplantation After Organ Donation Due to Hydrogen Sulfide Intoxication: Report of the First Case. Transplantation\| PubMed ID: 35333851	2022
Impact of perioperative blood transfusions on postoperative renal function and survival after resection of colorectal liver metastases. World journal of surgical oncology\| PubMed ID: 35354485	2022
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver. Science translational medicine\| PubMed ID: 35385339	2022
Corrigendum to 'Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model' [J Hepatol (2021) 1420-1433]. Journal of hepatology\| PubMed ID: 35397937	2022
Corrigendum to: 'Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis' [J Hepatol (2019) 722-734]. Journal of hepatology\| PubMed ID: 35397938	2022
Hypothermic Oxygenated Perfusion for Transplantation of a Pediatric Extended Right Lobe: Report of the First Case. Transplantation\| PubMed ID: 35616916	2022
Identification of structurally re-engineered rocaglates as inhibitors against hepatitis E virus replication. Antiviral research\| PubMed ID: 35728703	2022
A ribavirin-induced ORF2 single-nucleotide variant produces defective hepatitis E virus particles with immune decoy function. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 35969792	2022