Leonard Zon

Children's Hospital, Harvard Medical School

Affiliated withHarvard Medical School Children’s Hospital Boston

Research Area

Biography

Leonard Zon has not added Biography.
If you are Leonard Zon and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 17	2007
Publication title Cited by 93	2009

Other Publications

Article	Year
Organogenesis--heart and blood formation from the zebrafish point of view. Science (New York, N.Y.)\| PubMed ID: 11799232	2002
Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. Development (Cambridge, England)\| PubMed ID: 11830566	2002
Hematopoiesis and stem cells: plasticity versus developmental heterogeneity. Nature immunology\| PubMed ID: 11919568	2002
Walking the walk: migration and other common themes in blood and vascular development. Cell\| PubMed ID: 11955426	2002
Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11983906	2002
Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Developmental biology\| PubMed ID: 12051816	2002
Zebrafish as a cancer model system. Cancer cell\| PubMed ID: 12086858	2002
Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12142468	2002
Attack of the fish clones. Nature biotechnology\| PubMed ID: 12148002	2002
Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. Development (Cambridge, England)\| PubMed ID: 12183387	2002
Isolation and characterization of zebrafish NFE2. Physiological genomics\| PubMed ID: 12388799	2002
The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Blood\| PubMed ID: 12393445	2002
SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Molecular cell\| PubMed ID: 12419227	2002
SUMO-1 protease-1 regulates gene transcription through PML. Molecular cell\| PubMed ID: 12419228	2002
Portrait of a stem cell. Developmental cell\| PubMed ID: 12431368	2002
Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators. Experimental hematology\| PubMed ID: 12482499	2002
Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Current topics in developmental biology\| PubMed ID: 12510667	2003
Biomedicine. Love, honor, and protect (your liver). Science (New York, N.Y.)\| PubMed ID: 12574609	2003
Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.)\| PubMed ID: 12574629	2003
Characterization of embryonic globin genes of the zebrafish. Developmental biology\| PubMed ID: 12618133	2003
Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature genetics\| PubMed ID: 12669066	2003
Cancer genetics and drug discovery in the zebrafish. Nature reviews. Cancer\| PubMed ID: 12835673	2003
The zebrafish spi1 promoter drives myeloid-specific expression in stable transgenic fish. Blood\| PubMed ID: 12869502	2003
Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects. Mechanisms of development\| PubMed ID: 12915231	2003
The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans. Development (Cambridge, England)\| PubMed ID: 12952905	2003
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature\| PubMed ID: 13679919	2003
Modeling human hematopoietic and cardiovascular diseases in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 14579393	2003
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature immunology\| PubMed ID: 14608381	2003
Allan j. Erslev, m.d.: truly a great dane (1919-2003). Stem cells (Dayton, Ohio)\| PubMed ID: 14688399	2004
The zebrafish as a model organism to study development of the immune system. Advances in immunology\| PubMed ID: 14711058	2003
The pu.1 promoter drives myeloid gene expression in zebrafish. Blood\| PubMed ID: 14996705	2004
The use of zebrafish to understand immunity. Immunity\| PubMed ID: 15084267	2004
In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15123839	2004
Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood\| PubMed ID: 15142873	2004
Expression and mapping of duplicate neuropilin-1 and neuropilin-2 genes in developing zebrafish. Gene expression patterns : GEP\| PubMed ID: 15183302	2004
Taking the stem cell debate to the public. PLoS biology\| PubMed ID: 15208732	2004
Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish. Gene\| PubMed ID: 15302404	2004
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS biology\| PubMed ID: 15314655	2004
The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene\| PubMed ID: 15378083	2004
Analysis of hematopoietic development in the zebrafish. Methods in molecular medicine\| PubMed ID: 15492396	2005
Hematopoietic gene expression profile in zebrafish kidney marrow. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15520368	2004
The clinical potential of stem cells. Current opinion in cell biology\| PubMed ID: 15530786	2004
An Mll-dependent Hox program drives hematopoietic progenitor expansion. Current biology : CB\| PubMed ID: 15556871	2004
The chianti zebrafish mutant provides a model for erythroid-specific disruption of transferrin receptor 1. Development (Cambridge, England)\| PubMed ID: 15563524	2004
Use of the DsRed fluorescent reporter in zebrafish. Methods in cell biology\| PubMed ID: 15602868	2004
The Zon laboratory guide to positional cloning in zebrafish. Methods in cell biology\| PubMed ID: 15602919	2004
Zebrafish scl functions independently in hematopoietic and endothelial development. Developmental biology\| PubMed ID: 15617691	2005
Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Developmental cell\| PubMed ID: 15621534	2005
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15630097	2005
In vivo drug discovery in the zebrafish. Nature reviews. Drug discovery\| PubMed ID: 15688071	2005
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Current biology : CB\| PubMed ID: 15694309	2005
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nature genetics\| PubMed ID: 15735644	2005
The zebrafish: a new model of T-cell and thymic development. Nature reviews. Immunology\| PubMed ID: 15803150	2005
Mutant-specific gene programs in the zebrafish. Blood\| PubMed ID: 15827125	2005
The complex cartography of stem cell commitment. Cell\| PubMed ID: 15851023	2005
Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Developmental biology\| PubMed ID: 15893977	2005
Ferroportin1 is required for normal iron cycling in zebrafish. The Journal of clinical investigation\| PubMed ID: 15902304	2005
Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization. American journal of physiology. Renal physiology\| PubMed ID: 15914778	2005
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell metabolism\| PubMed ID: 16054062	2005
Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood\| PubMed ID: 16099879	2005
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis. Nature\| PubMed ID: 16110529	2005
Transcriptional regulation of hematopoietic stem cell development in zebrafish. Experimental hematology\| PubMed ID: 16140148	2005
A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16150706	2005
Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes & development\| PubMed ID: 16166372	2005
Zebrafish KLF4 is essential for anterior mesendoderm/pre-polster differentiation and hatching. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 16222715	2005
Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood\| PubMed ID: 16254142	2006
Use of the zebrafish system to study primitive and definitive hematopoiesis. Annual review of genetics\| PubMed ID: 16285869	2005
A critical role for calponin 2 in vascular development. The Journal of biological chemistry\| PubMed ID: 16317011	2006
Genetic analysis of cavefish reveals molecular convergence in the evolution of albinism. Nature genetics\| PubMed ID: 16341223	2006
Piloting the zebrafish genome browser. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 16372332	2006
Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nature chemical biology\| PubMed ID: 16372403	2005
The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Developmental biology\| PubMed ID: 16457800	2006
Mitoferrin is essential for erythroid iron assimilation. Nature\| PubMed ID: 16511496	2006
BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development (Cambridge, England)\| PubMed ID: 16672337	2006
AlphaA-crystallin expression prevents gamma-crystallin insolubility and cataract formation in the zebrafish cloche mutant lens. Development (Cambridge, England)\| PubMed ID: 16728471	2006
A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. Journal of cell science\| PubMed ID: 16968741	2006
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17068127	2006
A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chemical biology & drug design\| PubMed ID: 17105485	2006
Homing sweet homing: odyssey of hematopoietic stem cells. Immunity\| PubMed ID: 17174927	2006
A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes & development\| PubMed ID: 17210788	2007
Gene Duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a. PLoS genetics\| PubMed ID: 17257055	2007
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron\| PubMed ID: 17359917	2007
Zebrafish orthologs of human muscular dystrophy genes. BMC genomics\| PubMed ID: 17374169	2007
Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17416673	2007
Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & development\| PubMed ID: 17510286	2007
Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17517602	2007
New waves of discovery: modeling cancer in zebrafish. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 17557959	2007
Ultrasound biomicroscopy permits in vivo characterization of zebrafish liver tumors. Nature methods\| PubMed ID: 17572681	2007
The zebra fish cassiopeia mutant reveals that SIL is required for mitotic spindle organization. Molecular and cellular biology\| PubMed ID: 17576815	2007
Functional conservation of erythropoietin signaling in zebrafish. Blood\| PubMed ID: 17579187	2007
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature\| PubMed ID: 17581586	2007
Definition of the zebrafish genome using flow cytometry and cytogenetic mapping. BMC genomics\| PubMed ID: 17597531	2007
The zebrafish runzel muscular dystrophy is linked to the titin gene. Developmental biology\| PubMed ID: 17678642	2007
Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood\| PubMed ID: 17698971	2007
Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic research\| PubMed ID: 17968670	2008
APC and colon cancer: two hits for one. Nature medicine\| PubMed ID: 17987022	2007
Prostaglandin E2: making more of your marrow. Cell cycle (Georgetown, Tex.)\| PubMed ID: 18075310	2007
Combinatorial regulation of novel erythroid gene expression in zebrafish. Experimental hematology\| PubMed ID: 18243489	2008
Taking human cancer genes to the fish: a transgenic model of melanoma in zebrafish. Zebrafish\| PubMed ID: 18248215	2005
Hematopoiesis: an evolving paradigm for stem cell biology. Cell\| PubMed ID: 18295580	2008
SnapShot: hematopoiesis. Cell\| PubMed ID: 18295585	2008
Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE). Nature biotechnology\| PubMed ID: 18327244	2008
Cell stem cell. Cell stem cell\| PubMed ID: 18371324	2007
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. Cell stem cell\| PubMed ID: 18371359	2007
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. Cell stem cell\| PubMed ID: 18371423	2008
Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell stem cell\| PubMed ID: 18371439	2008
Use of zebrafish models for the analysis of human disease. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]\| PubMed ID: 18428328	2002
Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature\| PubMed ID: 18480811	2008
Zebrafish VEGF receptors: a guideline to nomenclature. PLoS genetics\| PubMed ID: 18516225	2008
Self-renewal and differentiation at Cell Stem Cell. Cell stem cell\| PubMed ID: 18522838	2008
montalcino, A zebrafish model for variegate porphyria. Experimental hematology\| PubMed ID: 18550261	2008
APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental biology\| PubMed ID: 18585699	2008
Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18729230	2008
Melanocytes in development, regeneration, and cancer. Cell stem cell\| PubMed ID: 18786412	2008
Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development (Cambridge, England)\| PubMed ID: 18799547	2008
Intestinal differentiation in zebrafish requires Cdx1b, a functional equivalent of mammalian Cdx2. Gastroenterology\| PubMed ID: 18804112	2008
A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. PloS one\| PubMed ID: 18846223	2008
Construction and application of a zebrafish array comparative genomic hybridization platform. Genes, chromosomes & cancer\| PubMed ID: 18973135	2009
Transferrin-a modulates hepcidin expression in zebrafish embryos. Blood\| PubMed ID: 19047682	2009
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology\| PubMed ID: 19073184	2009
Melanoma biology and the promise of zebrafish. Zebrafish\| PubMed ID: 19133823	2008
The effect of a depth gradient on the mating behavior, oviposition site preference, and embryo production in the zebrafish, Danio rerio. Zebrafish\| PubMed ID: 19133832	2008
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell\| PubMed ID: 19303855	2009
A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood\| PubMed ID: 19332767	2009
Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Molecular and cellular biology\| PubMed ID: 19380487	2009
Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood\| PubMed ID: 19433857	2009
Hematopoietic stem cell development is dependent on blood flow. Cell\| PubMed ID: 19450519	2009
Zebrafish blood stem cells. Journal of cellular biochemistry\| PubMed ID: 19565566	2009
Defining cancer stem cells by xenotransplantation in zebrafish. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19582417	2009
Chemical genetic screening in the zebrafish embryo. Nature protocols\| PubMed ID: 19745824	2009
Melanocytes in development and cancer. Journal of cellular physiology\| PubMed ID: 19795394	2010
Oncogenic NRAS cooperates with p53 loss to generate melanoma in zebrafish. Zebrafish\| PubMed ID: 19954345	2009
Zebrafish tumor assays: the state of transplantation. Zebrafish\| PubMed ID: 20047467	2009
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia. Blood\| PubMed ID: 20056790	2010
Derivation of adult stem cells during embryogenesis. Harvey lectures\| PubMed ID: 20166566	2006
Swimming into the future of drug discovery: in vivo chemical screens in zebrafish. ACS chemical biology\| PubMed ID: 20166761	2010
Resolving the controversy about N-cadherin and hematopoietic stem cells. Cell stem cell\| PubMed ID: 20207222	2010
Small molecule screen in zebrafish and HSC expansion. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20336531	2010
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.)\| PubMed ID: 20339075	2010
Interaction of retinoic acid and scl controls primitive blood development. Blood\| PubMed ID: 20410509	2010
The new age of chemical screening in zebrafish. Zebrafish\| PubMed ID: 20415642	2010
A chemical genetic screen in zebrafish for pathways interacting with cdx4 in primitive hematopoiesis. Zebrafish\| PubMed ID: 20415644	2010
Newly emerging roles for prostaglandin E2 regulation of hematopoiesis and hematopoietic stem cell engraftment. Current opinion in hematology\| PubMed ID: 20473159	2010
Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica\| PubMed ID: 20494928	2010
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell\| PubMed ID: 20603019	2010
Blood flow: metalloproteases cut loose in primitive erythrocytes. Current biology : CB\| PubMed ID: 20619808	2010
Fishing at the cellular level. Nature methods\| PubMed ID: 20676080	2010
Zebrafish models of p53 functions. Cold Spring Harbor perspectives in biology\| PubMed ID: 20679337	2010
Hematopoietic development in the zebrafish. The International journal of developmental biology\| PubMed ID: 20711990	2010
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20855591	2010
T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer cell\| PubMed ID: 20951945	2010
The zebrafish: cellular and developmental biology, part A. Preface. Methods in cell biology\| PubMed ID: 21111211	2010
Stem cells: The blood balance. Nature\| PubMed ID: 21124447	2010
Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (Cambridge, England)\| PubMed ID: 21138979	2011
Lessons from the Niche for Generation and Expansion of Hematopoietic Stem Cells. Drug discovery today. Therapeutic strategies\| PubMed ID: 21212834	2009
The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Human molecular genetics\| PubMed ID: 21296866	2011
The ERGonomics of hematopoietic stem cell self-renewal. Genes & development\| PubMed ID: 21325129	2011
cpsf1 is required for definitive HSC survival in zebrafish. Blood\| PubMed ID: 21330472	2011
Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. Muscle & nerve\| PubMed ID: 21337346	2011
Characterization of immune-matched hematopoietic transplantation in zebrafish. Blood\| PubMed ID: 21346254	2011
Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood\| PubMed ID: 21415264	2011
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature\| PubMed ID: 21430779	2011
DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature\| PubMed ID: 21430780	2011
Modeling Diamond Blackfan anemia in the zebrafish. Seminars in hematology\| PubMed ID: 21435504	2011
Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell stem cell\| PubMed ID: 21474107	2011
Stem cell migration: a zebrafish model. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21618090	2011
Stromal cell-derived factor-1 and hematopoietic cell homing in an adult zebrafish model of hematopoietic cell transplantation. Blood\| PubMed ID: 21622651	2011
Zebrafish as a model for normal and malignant hematopoiesis. Disease models & mechanisms\| PubMed ID: 21708900	2011
A new system for the rapid collection of large numbers of developmentally staged zebrafish embryos. PloS one\| PubMed ID: 21738776	2011
Genetic suppressor screens in haploids. Methods in cell biology\| PubMed ID: 21924160	2011
Advanced zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments. Methods in cell biology\| PubMed ID: 21924163	2011
The zon laboratory guide to positional cloning in zebrafish. Methods in cell biology\| PubMed ID: 21924169	2011
Chromatin immunoprecipitation in adult zebrafish red cells. Methods in cell biology\| PubMed ID: 21924172	2011
The NOTCH pathway contributes to cell fate decision in myelopoiesis. Haematologica\| PubMed ID: 21933862	2011
Transplantation in zebrafish. Methods in cell biology\| PubMed ID: 21951540	2011
Chemical screening in zebrafish for novel biological and therapeutic discovery. Methods in cell biology\| PubMed ID: 21951544	2011
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell\| PubMed ID: 22036566	2011
The zebrafish. Preface. Methods in cell biology\| PubMed ID: 22043535	2011
Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation. Experimental hematology\| PubMed ID: 22120640	2012
An optical platform for cell tracking in adult zebrafish. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 22162445	2012
Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22203992	2012
Hematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish model. Genome medicine\| PubMed ID: 22206610	2011
Linking hematopoietic regeneration to developmental signaling pathways: A story of BMP and Wnt. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22262185	2012
Stem cells: The right neighbour. Nature\| PubMed ID: 22281591	2012
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Molecular cell\| PubMed ID: 22325351	2012
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental cell\| PubMed ID: 22421047	2012
Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Developmental biology\| PubMed ID: 22537494	2012
A great match. Cell stem cell\| PubMed ID: 22704496	2012
Hooked! Modeling human disease in zebrafish. The Journal of clinical investigation\| PubMed ID: 22751109	2012
Histocompatibility and hematopoietic transplantation in the zebrafish. Advances in hematology\| PubMed ID: 22778744	2012
Cancer and inflammation: an aspirin a day keeps the cancer at bay. Current biology : CB\| PubMed ID: 22789999	2012
Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood\| PubMed ID: 22936663	2012
Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. PLoS genetics\| PubMed ID: 22952453	2012
A splice site mutation in laminin-α2 results in a severe muscular dystrophy and growth abnormalities in zebrafish. PloS one\| PubMed ID: 22952766	2012
Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Developmental biology\| PubMed ID: 22960038	2013
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell\| PubMed ID: 22980977	2012
In situ hybridization assay-based small molecule screening in zebrafish. Current protocols in chemical biology\| PubMed ID: 23001521	2012
CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nature genetics\| PubMed ID: 23023333	2012
The transcriptional landscape of hematopoietic stem cell ontogeny. Cell stem cell\| PubMed ID: 23122293	2012
TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes. Developmental biology\| PubMed ID: 23159334	2013
Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. Developmental biology\| PubMed ID: 23220656	2013
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23236128	2013
Ageing: Stem cells on a stress-busting diet. Nature\| PubMed ID: 23389448	2013
Potential of zebrafish for anticancer drug screening. Expert opinion on drug discovery\| PubMed ID: 23506108	2008
A model for primary melanoma of the CNS implicates NRAS. Cancer discovery\| PubMed ID: 23580282	2013
The zebrafish reference genome sequence and its relationship to the human genome. Nature\| PubMed ID: 23594743	2013
A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development. Development (Cambridge, England)\| PubMed ID: 23615277	2013
The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish. PloS one\| PubMed ID: 23705022	2013
Hematopoiesis. Development (Cambridge, England)\| PubMed ID: 23715539	2013
Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 23723152	2013
Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley interdisciplinary reviews. Developmental biology\| PubMed ID: 23801494	2012
Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. Development (Cambridge, England)\| PubMed ID: 23821038	2013
Assaying hematopoiesis using zebrafish. Blood cells, molecules & diseases\| PubMed ID: 23916372	2013
Zebrafish cancer: the state of the art and the path forward. Nature reviews. Cancer\| PubMed ID: 23969693	2013
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood\| PubMed ID: 23996087	2013
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell stem cell\| PubMed ID: 24094326	2013
The zebrafish granulocyte colony stimulating factors (Gcsfs): two paralogous cytokines and their roles in hematopoietic development and maintenance. Blood\| PubMed ID: 24128862	2013
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome biology\| PubMed ID: 24148783	2013
zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish. Development (Cambridge, England)\| PubMed ID: 24198277	2013
A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species. Cell\| PubMed ID: 24209627	2013
A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology\| PubMed ID: 24240475	2013
Of fish and men: using zebrafish to fight human diseases. Trends in cell biology\| PubMed ID: 24275383	2013
A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem cell reports\| PubMed ID: 24286030	2013
Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development (Cambridge, England)\| PubMed ID: 24346703	2014
A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nature communications\| PubMed ID: 24496182	2014
Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development. PLoS genetics\| PubMed ID: 24497835	2014
Translational research: the path for bringing discovery to patients. Cell stem cell\| PubMed ID: 24506882	2014
Unexpectedly uneven: posttransplant skeletal distribution of hematopoietic stem cell clones. The Journal of experimental medicine\| PubMed ID: 24616474	2014
Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. American journal of human genetics\| PubMed ID: 24656866	2014
Neural crest development and craniofacial morphogenesis is coordinated by nitric oxide and histone acetylation. Chemistry & biology\| PubMed ID: 24684905	2014
Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families. Blood\| PubMed ID: 24829207	2014
Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood\| PubMed ID: 24869937	2014
From fish tank to bedside in cancer therapy: an interview with Leonard Zon. Disease models & mechanisms\| PubMed ID: 24973742	2014
Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology\| PubMed ID: 25004091	2014
Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2. Experimental cell research\| PubMed ID: 25094063	2014
Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic acids research\| PubMed ID: 25223788	2014
A comparison of non-integrating reprogramming methods. Nature biotechnology\| PubMed ID: 25437882	2015
A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing. Molecular and cellular biology\| PubMed ID: 25512612	2015
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. Blood\| PubMed ID: 25587036	2015
Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell\| PubMed ID: 25594182	2015
Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. eLife\| PubMed ID: 25714926	2015
A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish. Developmental cell\| PubMed ID: 25752963	2015
Screening for melanoma resistance genes in vivo. Pigment cell & melanoma research\| PubMed ID: 25818368	2015