Laura M. Sly

Department of Pediatrics, University of British Columbia

Affiliated withUniversity of British Columbia University of British Columbia University of British Columbia and BC Children's Hospital Research Institute

Research Area

Immunology and Infection

Biography

Laura M. Sly has not added Biography.
If you are Laura M. Sly and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 117	2012
Publication title Cited by 7	2017
Publication title	2025

Other Publications

Article	Year
Salmonella enterica serovar Typhimurium periplasmic superoxide dismutases SodCI and SodCII are required for protection against the phagocyte oxidative burst. Infection and immunity\| PubMed ID: 12183590	2002
Survival of Mycobacterium tuberculosis in host macrophages involves resistance to apoptosis dependent upon induction of antiapoptotic Bcl-2 family member Mcl-1. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12496428	2003
The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12594264	2003
Experimental hematology\| PubMed ID: 14662322	2003
Immunity\| PubMed ID: 15308103	2004
Immunity\| PubMed ID: 16226502	2005
Blood\| PubMed ID: 16861351	2006
Monocyte p110alpha phosphatidylinositol 3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine production. Journal of leukocyte biology\| PubMed ID: 17369495	2007
The role of SHIP in macrophages. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 17485263	2007
Experimental hematology\| PubMed ID: 18375036	2008
The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo. Infection and immunity\| PubMed ID: 18426884	2008
Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18768839	2008
SHIP prevents lipopolysaccharide from triggering an antiviral response in mice. Blood\| PubMed ID: 19139077	2009
Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19347318	2009
SHIP regulates the reciprocal development of T regulatory and Th17 cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19542365	2009
Blood\| PubMed ID: 19667399	2009
SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19710468	2009
The p110α and p110β isoforms of class I phosphatidylinositol 3-kinase are involved in toll-like receptor 5 signaling in epithelial cells. Mediators of inflammation\| PubMed ID: 20953381	2010
SHIP represses Th2 skewing by inhibiting IL-4 production from basophils. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21131429	2011
Alternative activation of macrophages by IL-4 requires SHIP degradation. European journal of immunology\| PubMed ID: 21469115	2011
SHIP-deficient mice develop spontaneous intestinal inflammation and arginase-dependent fibrosis. The American journal of pathology\| PubMed ID: 21640975	2011
A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation. Cancer research\| PubMed ID: 21673053	2011
SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis. Journal of leukocyte biology\| PubMed ID: 21685246	2011
Generation and characterization of murine alternatively activated macrophages. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23179835	2013
Combined immunodeficiency associated with homozygous MALT1 mutations. The Journal of allergy and clinical immunology\| PubMed ID: 24332264	2014
Arginase activity in alternatively activated macrophages protects PI3Kp110δ deficient mice from dextran sodium sulfate induced intestinal inflammation. European journal of immunology\| PubMed ID: 25124254	2014
Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. European journal of immunology\| PubMed ID: 25311115	2015
Phosphatase regulation of macrophage activation. Seminars in immunology\| PubMed ID: 26216598	2015
Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state. Journal of leukocyte biology\| PubMed ID: 26216934	2015
Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease. Gastroenterology\| PubMed ID: 26481854	2016
Endosomal pH modulation by peptide-gold nanoparticle hybrids enables potent anti-inflammatory activity in phagocytic immune cells. Biomaterials\| PubMed ID: 27728817	2016
IFN-γ directly inhibits murine B-cell precursor leukemia-initiating cell proliferation early in life. European journal of immunology\| PubMed ID: 28295300	2017
Macrophage immunotherapy: overcoming impediments to realize promise. Trends in immunology\| PubMed ID: 36441083	2022