Carsten Korth

Department of Neuropathology, Medical School Düsseldorf, Germany

Affiliated withMedical School Düsseldorf, Germany Medical School Düsseldorf

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 13	2012
Publication title Cited by 7	2013

Other Publications

Article	Year
Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12684540	2003
The expanded octarepeat domain selectively binds prions and disrupts homomeric prion protein interactions. The Journal of biological chemistry\| PubMed ID: 16352600	2006
Prion protein gene codon 129 modulates clinical course of neurological Wilson disease. Neuroreport\| PubMed ID: 16543824	2006
Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Archives of neurology\| PubMed ID: 16606761	2006
Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments. Journal of neurochemistry\| PubMed ID: 16749906	2006
Similar structure-activity relationships of quinoline derivatives for antiprion and antimalarial effects. Journal of medicinal chemistry\| PubMed ID: 16913719	2006
A chimeric ligand approach leading to potent antiprion active acridine derivatives: design, synthesis, and biological investigations. Journal of medicinal chemistry\| PubMed ID: 17064077	2006
The use of conformation-specific ligands and assays to dissect the molecular mechanisms of neurodegenerative diseases. Journal of neuroscience research\| PubMed ID: 17497676	2007
Vaccine approaches to prevent and treat prion infection : progress and challenges. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 18215090	2008
Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18400883	2008
Expansion of the octarepeat domain alters the misfolding pathway but not the folding pathway of the prion protein. Biochemistry\| PubMed ID: 18473442	2008
Genes contributing to prion pathogenesis. The Journal of general virology\| PubMed ID: 18559949	2008
Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity. Molecular immunology\| PubMed ID: 18973947	2009
Quinpramine 是一个新型的复合有效改善大脑自身免疫性疾病。 Experimental neurology\| PubMed ID: 18996373	2009
Genetic polymorphism at codon 129 of the prion protein gene is not associated with multiple sclerosis. Archives of neurology\| PubMed ID: 19204171	2009
Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C. Biochemistry\| PubMed ID: 19583211	2009
Binding of TCA to the prion protein: mechanism, implication for therapy, and application as probe for complex formation of bio-macromolecules. Journal of biomolecular structure & dynamics\| PubMed ID: 19583442	2009
alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. Journal of neurochemistry\| PubMed ID: 19804379	2009
Understanding the role of DISC1 in psychiatric disease and during normal development. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19828788	2009
Structure-activity relationship of tocopherol derivatives suggesting a novel non-antioxidant mechanism in antiprion potency. Neuroscience letters\| PubMed ID: 19945507	2010
Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism. Biochemical and biophysical research communications\| PubMed ID: 20138835	2010
Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling. Brain : a journal of neurology\| PubMed ID: 20145049	2010
Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20212127	2010
DISCopathies: brain disorders related to DISC1 dysfunction. Reviews in the neurosciences\| PubMed ID: 20397618	2009
Codon 129 polymorphism and the E200K mutation do not affect the cellular prion protein isoform composition in the cerebrospinal fluid from patients with Creutzfeldt-Jakob disease. The European journal of neuroscience\| PubMed ID: 20529115	2010
Quinpramine--a promising compound for treating immune-mediated demyelination of the nervous system. Drug news & perspectives\| PubMed ID: 20603652	2010
Human prion strain selection in transgenic mice. Annals of neurology\| PubMed ID: 20695008	2010
Combining independent drug classes into superior, synergistically acting hybrid molecules. Angewandte Chemie (International ed. in English)\| PubMed ID: 20922735	2010
Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to Î³-secretase modulators regardless of thei... Journal of neurochemistry\| PubMed ID: 21091478	2011
No association between genetic polymorphism at codon 129 of the prion protein gene and primary progressive multiple sclerosis. Archives of neurology\| PubMed ID: 21320996	2011
Biological effects and use of PrPSc- and PrP-specific antibodies generated by immunization with purified full-length native mouse prions. Journal of virology\| PubMed ID: 21345946	2011
Convergence of two independent mental disease genes on the protein level: recruitment of dysbindin to cell-invasive disrupted-in-schizophrenia 1 aggresomes. Biological psychiatry\| PubMed ID: 21531389	2011
Quinpramine ameliorates rat experimental autoimmune neuritis and redistributes MHC class II molecules. PloS one\| PubMed ID: 21698177	2011
Rapidly progressive Alzheimer disease. Archives of neurology\| PubMed ID: 21911694	2011
Hybrid compounds: from simple combinations to nanomachines. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 22239618	2012
Cellular prion protein participates in amyloid-Î² transcytosis across the blood-brain barrier. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 22293988	2012
Aggregated proteins in schizophrenia and other chronic mental diseases: DISC1opathies. Prion\| PubMed ID: 22421208	2012
Identification of I137M and other mutations that modulate incubation periods for two human prion strains. Journal of virology\| PubMed ID: 22438549	2012
C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-Î². Brain : a journal of neurology\| PubMed ID: 22637581	2012
Human and rat brain lipofuscin proteome. Proteomics\| PubMed ID: 22707227	2012
Identification of Dominant Human Aquaporin 4 T-Cell Epitopes: Observations in Neuromyelitis Optica With Implications for Other Autoimmune DisordershAQP4 T-Cell Epitopes. Archives of neurology\| PubMed ID: 22751933	2012
Oral Treatment with the d-Enantiomeric Peptide D3 Improves the Pathology and Behavior of Alzheimer's Disease Transgenic Mice. ACS chemical neuroscience\| PubMed ID: 22778851	2010
Molecular engineering of a secreted, highly homogeneous, and neurotoxic aÎ² dimer. ACS chemical neuroscience\| PubMed ID: 22778868	2011
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Human molecular genetics\| PubMed ID: 22798627	2012
On the issue of transmissibility of Alzheimer disease: a critical review. Prion\| PubMed ID: 23052009	2012
Characterization of a single-chain variable fragment recognizing a linear epitope of aÎ²: a biotechnical tool for studies on Alzheimer's disease? PloS one\| PubMed ID: 23555792	2013
Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid Î²-peptide. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis\| PubMed ID: 23829200	2013
Revisiting Disrupted in Schizophrenia 1 as a scaffold protein. Biological chemistry\| PubMed ID: 23832957	2013
Regulation of N-Methyl-D-Aspartate Receptors by Disrupted-in-Schizophrenia-1. Biological psychiatry\| PubMed ID: 23906531	2013