Michael T. Longaker

Michael T. Longaker

Department of Surgery, Stanford University

Affiliated withStanford University Stanford University School of MedicineStanford University

Research Area

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JoVE Journal Publications

ArticleTotal : 10
Year
Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate
Publication title

Cited by 21

2012
2014
2015
2015
2015

Other Publications

Article
Year
Tissue engineering in cleft palate and other congenital malformations.

Pediatric research| PubMed ID: 18427300

2008
2006
2006
Age-dependent residual tensile strains are present in the dura mater of rats.

Journal of the Royal Society, Interface / the Royal Society| PubMed ID: 16849176

2005
2006
2006
Novel techniques in hernia repair.

Current surgery| PubMed ID: 16971199

2006
2006
Cyclophilin C-associated protein is up-regulated during wound healing.

Journal of cellular physiology| PubMed ID: 16998803

2007
Early-gestation fetal scarless wounds have less lysyl oxidase expression.

Plastic and reconstructive surgery| PubMed ID: 17016177

2006
2006
The ethics of innovation in pediatric surgery.

Seminars in pediatric surgery| PubMed ID: 17055963

2006
Innovation in surgery: a historical perspective.

Annals of surgery| PubMed ID: 17060760

2006
Progress and potential for regenerative medicine.

Annual review of medicine| PubMed ID: 17076602

2007
2006
Microvascular reconstruction of the pediatric mandible.

Plastic and reconstructive surgery| PubMed ID: 17230103

2007
2007
2007
2007
Registering clinical trials in plastic and reconstructive surgery.

Plastic and reconstructive surgery| PubMed ID: 17312519

2007
2007
2007
2007
2007
Proposition 71 and CIRM--assessing the return on investment.

Nature biotechnology| PubMed ID: 17483831

2007
Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 17504973

2007
2007
2007
2007
2007
Overhealing, underhealing, and skin regeneration: a new perspective on wound healing.

Asian journal of surgery / Asian Surgical Association| PubMed ID: 17585454

2002
Accelerated bone repair after plasma laser corticotomies.

Annals of surgery| PubMed ID: 17592303

2007
2007
2007
2008
2007
Dura mater-derived FGF-2 mediates mitogenic signaling in calvarial osteoblasts.

American journal of physiology. Cell physiology| PubMed ID: 17913846

2007
2007
2007
Live imaging of Smad2/3 signaling in mouse skin wound healing.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 17971023

2007
Use of organotypic coculture to study keloid biology.

American journal of surgery| PubMed ID: 18070722

2008
2007
2008
2008
2008
2008
Blood-derived small Dot cells reduce scar in wound healing.

Experimental cell research| PubMed ID: 18295204

2008
Cranial sutures: a brief review.

Plastic and reconstructive surgery| PubMed ID: 18349596

2008
Current progress in keloid research and treatment.

Journal of the American College of Surgeons| PubMed ID: 18387480

2008
2008
2008
Identification of differentially regulated genes in fetal wounds during regenerative repair.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 18471263

2008
Wound repair and regeneration.

Nature| PubMed ID: 18480812

2008
2008
Mesenchymal cells for skeletal tissue engineering.

Expert opinion on biological therapy| PubMed ID: 18549320

2008
2008
Dissecting the influence of regional dura mater on cranial suture biology.

Plastic and reconstructive surgery| PubMed ID: 18594389

2008
Microarray analysis of the role of regional dura mater in cranial suture fate.

Plastic and reconstructive surgery| PubMed ID: 18626354

2008
2008
Cell-based therapies for skeletal regenerative medicine.

Human molecular genetics| PubMed ID: 18632703

2008
Regenerative medicine: the next frontier.

Transplantation| PubMed ID: 18645480

2008
Advances in science and technology: impact on craniofacial surgery.

The Journal of craniofacial surgery| PubMed ID: 18650748

2008
2008
2008
2008
2009
Global age-dependent differences in gene expression in response to calvarial injury.

The Journal of craniofacial surgery| PubMed ID: 18812854

2008
2008
Plastic surgery and the society of university surgeons: an expanding relationship.

Plastic and reconstructive surgery| PubMed ID: 18971743

2008
2009
2008
2009
2009
2009
2009
2009
2009
Craniofacial autologous fat transfer.

The Journal of craniofacial surgery| PubMed ID: 19305242

2009
Perspectives in cell-based skeletal tissue.

The Journal of craniofacial surgery| PubMed ID: 19305243

2009
2009
Ethnic diversity remains scarce in academic plastic and reconstructive surgery.

Plastic and reconstructive surgery| PubMed ID: 19407636

2009
The use of polymer scaffolds in skeletal tissue engineering applications.

The Journal of craniofacial surgery| PubMed ID: 19461326

2009
2009
2009
Ex vivo model of cranial suture morphogenesis and fate.

Cells, tissues, organs| PubMed ID: 19590164

2009
Unfolded protein response regulation in keloid cells.

The Journal of surgical research| PubMed ID: 19631342

2011
2009
Fetal skin wound healing.

Advances in clinical chemistry| PubMed ID: 19803418

2009
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19805220

2009
Bone tissue engineering scaffolds of today and tomorrow.

The Journal of craniofacial surgery| PubMed ID: 19816291

2009
2010
Human skin wounds: a major and snowballing threat to public health and the economy.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 19903300

2009
Origin matters: differences in embryonic tissue origin and Wnt signaling determine the osteogenic potential and healing capacity of frontal and parietal calvarial bones.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research| PubMed ID: 19929441

2010
From bedside to bench and back again: technology innovation in plastic surgery.

Plastic and reconstructive surgery| PubMed ID: 19935323

2009
Bone regeneration and repair.

Current stem cell research & therapy| PubMed ID: 19941457

2010
2009
2010
2010
2010
Regenerative medicine: a surgeon's perspective.

Journal of pediatric surgery| PubMed ID: 20105574

2010
2010
2010
2010
2010
Human iPS cell-based therapy: considerations before clinical applications.

Cell cycle (Georgetown, Tex.)| PubMed ID: 20160515

2010
2010
2010
2010
In vitro effects of direct current electric fields on adipose-derived stromal cells.

Biochemical and biophysical research communications| PubMed ID: 20452327

2010
2010
2010
2011
2010
Fgf-9 is required for angiogenesis and osteogenesis in long bone repair.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20547837

2010
Stem cells.

Plastic and reconstructive surgery| PubMed ID: 20555302

2010
2010
2010
2010
2010
Commentary.

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery| PubMed ID: 20601561

2010
2010
2010
2011
Elastic properties of induced pluripotent stem cells.

Tissue engineering. Part A| PubMed ID: 20807017

2011
2010
2010
Tissue engineering in plastic surgery: a review.

Plastic and reconstructive surgery| PubMed ID: 20811219

2010
So you want to be an innovator?

Plastic and reconstructive surgery| PubMed ID: 20811242

2010
2010
2010
Scarless fetal wound healing: a basic science review.

Plastic and reconstructive surgery| PubMed ID: 20885241

2010
2011
The basic science of vascular biology: implications for the practicing surgeon.

Plastic and reconstructive surgery| PubMed ID: 21042110

2010
Basic science review on adipose tissue for clinicians.

Plastic and reconstructive surgery| PubMed ID: 21124133

2010
2010
2010
Surgical approaches to create murine models of human wound healing.

Journal of biomedicine & biotechnology| PubMed ID: 21151647

2011
Strategies for organ level tissue engineering.

Organogenesis| PubMed ID: 21197216

2010
Salvage of the crucified chin.

Plastic and reconstructive surgery| PubMed ID: 21200230

2011
The role of stem cells in cutaneous wound healing: what do we really know?

Plastic and reconstructive surgery| PubMed ID: 21200267

2011
2011
Deformational plagiocephaly: a look into the future.

The Journal of craniofacial surgery| PubMed ID: 21239916

2011
2011
Differential expression of sclerostin in adult and juvenile mouse calvariae.

Plastic and reconstructive surgery| PubMed ID: 21285764

2011
2011
In brief: Regenerative medicine.

Current problems in surgery| PubMed ID: 21295631

2011
Regenerative medicine.

Current problems in surgery| PubMed ID: 21295632

2011
2011
2011
2011
Role of Indian hedgehog signaling in palatal osteogenesis.

Plastic and reconstructive surgery| PubMed ID: 21364421

2011
Research training in plastic surgery.

The Journal of craniofacial surgery| PubMed ID: 21415623

2011
2011
Osteogenic differentiation of human multipotent mesenchymal stromal cells.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 21431521

2011
2011
2011
2011
2011
2011
2011
2012
2011
2011
2011
Pushing back: wound mechanotransduction in repair and regeneration.

The Journal of investigative dermatology| PubMed ID: 21776006

2011
2011
Recommendations on clinical proof of efficacy for potential scar prevention and reduction therapies.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 21793964

2011
2011
2011
2011
2012
Mechanical force prolongs acute inflammation via T-cell-dependent pathways during scar formation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 21911593

2011
2012
2011
Commentary on role of apoptosis in retinoic Acid-induced cleft palate.

The Journal of craniofacial surgery| PubMed ID: 21959389

2011
2012
2011
2011
2011
2011
2011
2012
Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22178754

2012
2011
Large Animal Induced Pluripotent Stem Cells as Pre-Clinical Models For Studying Human Disease.

Journal of cellular and molecular medicine| PubMed ID: 22212700

2012
Craniofacial surgery: innovation, design, and strategy.

The Journal of craniofacial surgery| PubMed ID: 22337364

2012
Cranial suture biology: from pathways to patient care.

The Journal of craniofacial surgery| PubMed ID: 22337368

2012
Stem cells: update and impact on craniofacial surgery.

The Journal of craniofacial surgery| PubMed ID: 22337434

2012
Training the contemporary surgeon-scientist.

Plastic and reconstructive surgery| PubMed ID: 22456371

2012
2012
Rethinking the blastema.

Plastic and reconstructive surgery| PubMed ID: 22544093

2012
2012
Craniofacial reconstruction with induced pluripotent stem cells.

The Journal of craniofacial surgery| PubMed ID: 22627398

2012
Stem cell niches for skin regeneration.

International journal of biomaterials| PubMed ID: 22701121

2012
2012
2012
Soft tissue mechanotransduction in wound healing and fibrosis.

Seminars in cell & developmental biology| PubMed ID: 23036529

2012
2012
Introduction: Wound repair.

Seminars in cell & developmental biology| PubMed ID: 23059792

2012
Scarless fetal skin wound healing update.

Birth defects research. Part C, Embryo today : reviews| PubMed ID: 23109319

2012
2012
2014
2015
2015
2015
2015
2015
2015
2015
2015
2015
2015
Autologous Fat Grafting: The Science Behind the Surgery.

Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery| PubMed ID: 26961989

2016
2016
The role of stem cells in limb regeneration.

Organogenesis| PubMed ID: 27008101

2016
2016
2016
2016
2016
Stem Cells in Bone Regeneration.

Stem cell reviews| PubMed ID: 27250635

2016
Scarless wound healing: finding the right cells and signals.

Cell and tissue research| PubMed ID: 27256396

2016
2016
2016
2016
2016
Dipeptidyl Peptidase-4, Wound Healing, Scarring, and Fibrosis.

Plastic and reconstructive surgery| PubMed ID: 27782998

2016
Getting nervous about regeneration.

Stem cell investigation| PubMed ID: 27868053

2016
Minimizing Skin Scarring through Biomaterial Design.

Journal of functional biomaterials| PubMed ID: 28117733

2017
2017
Biomimetics of Bone Implants: The Regenerative Road.

BioResearch open access| PubMed ID: 28163982

2017
2017
2017
2017
Laboratory Models for the Study of Normal and Pathologic Wound Healing.

Plastic and reconstructive surgery| PubMed ID: 28234843

2017
2017
2017
A Review of Cell-Based Strategies for Soft Tissue Reconstruction.

Tissue engineering. Part B, Reviews| PubMed ID: 28372485

2017
Isolation of CD248-expressing stromal vascular fraction for targeted improvement of wound healing.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 28464475

2017
2017
2017
2017
Cell-Based Soft Tissue Reconstruction in a Hydrogel Scaffold.

Annals of plastic surgery| PubMed ID: 28671889

2017
Strategic Targeting of Multiple BMP Receptors Prevents Trauma-Induced Heterotopic Ossification.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 28716575

2017
2017
2017
2017
2017
A MUSE for Skin Regeneration.

The Journal of investigative dermatology| PubMed ID: 29169463

2017
PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing.

Plastic and reconstructive surgery| PubMed ID: 29280872

2018
Inhibition of IRE1 results in decreased scar formation.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 29316036

2017
Scarless wound healing: Transitioning from fetal research to regenerative healing.

Wiley interdisciplinary reviews. Developmental biology| PubMed ID: 29316315

2018
2018
2018
Noncoding RNAs in Wound Healing: A New and Vast Frontier.

Advances in wound care| PubMed ID: 29344431

2018
2018
2018
Review of the Current Management of Pressure Ulcers.

Advances in wound care| PubMed ID: 29392094

2018
Embryonic skin development and repair.

Organogenesis| PubMed ID: 29420124

2018
β-Catenin-Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding.

Plastic and reconstructive surgery| PubMed ID: 29481398

2018
A Fibroblast Is Not a Fibroblast Is Not a Fibroblast.

The Journal of investigative dermatology| PubMed ID: 29579454

2018
2018
2018
2018
Fibroblasts and wound healing: an update.

Regenerative medicine| PubMed ID: 30062921

2018
2018
2018
fibroblasts and melanoma.

Melanoma management| PubMed ID: 30190847

2015
Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue.

Tissue engineering. Part C, Methods| PubMed ID: 30215305

2018
2018
DEL1 protects against chondrocyte apoptosis through integrin binding.

The Journal of surgical research| PubMed ID: 30278915

2018
Management of Chronic Wounds-2018.

JAMA| PubMed ID: 30326512

2018
2018
2018
2018
2018
In Vitro and In Vivo Osteogenic Differentiation of Human Adipose-Derived Stromal Cells.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 30414122

2019
Small molecule inhibition of dipeptidyl peptidase-4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds.

Translational research : the journal of laboratory and clinical medicine| PubMed ID: 30452888

2019
Discussion: CRISPR Craft: DNA Editing the Reconstructive Ladder.

Plastic and reconstructive surgery| PubMed ID: 30511993

2018
2020
Fat Grafting into Younger Recipients Improves Volume Retention in an Animal Model.

Plastic and reconstructive surgery| PubMed ID: 30730498

2019
2019
2019
Wounds Inhibit Tumor Growth In Vivo.

Annals of surgery| PubMed ID: 30829705

2021
Fat Chance: The Rejuvenation of Irradiated Skin.

Plastic and reconstructive surgery. Global open| PubMed ID: 30881833

2019
2020
The Spectrum of Scarring in Craniofacial Wound Repair.

Frontiers in physiology| PubMed ID: 30984020

2019
2020
Pressure Injury.

Annals of surgery| PubMed ID: 31460882

2020
2019
2019
2019
2019
A Revised Perspective of Skeletal Stem Cell Biology.

Frontiers in cell and developmental biology| PubMed ID: 31572721

2019
2019
2019
2019
A fine balance in tendon healing.

Nature cell biology| PubMed ID: 31768049

2019
Fat grafting rescues radiation-induced joint contracture.

Stem cells (Dayton, Ohio)| PubMed ID: 31793745

2020
Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 32161098

2020
2020
"Tissues in a Dish": A Review of Organoids in Plastic Surgery.

Plastic and reconstructive surgery. Global open| PubMed ID: 32440447

2020
Macrophage Subpopulation Dynamics Shift following Intravenous Infusion of Mesenchymal Stromal Cells.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 32531238

2020
Understanding the impact of fibroblast heterogeneity on skin fibrosis.

Disease models & mechanisms| PubMed ID: 32541065

2020
2020
2020
2020
2020
2020
2020
2020
2020
Mechanisms of bone development and repair.

Nature reviews. Molecular cell biology| PubMed ID: 32901139

2020
2020
Exosomes: A Tool for Bone Tissue Engineering.

Tissue engineering. Part B, Reviews| PubMed ID: 33297857

2022
Craniofacial and Long Bone Development in the Context of Distraction Osteogenesis.

Plastic and reconstructive surgery| PubMed ID: 33370054

2021
Proceed with Caution: Mouse Deep Digit Flexor Tendon Injury Model.

Plastic and reconstructive surgery. Global open| PubMed ID: 33552814

2021
2021
Deferoxamine to Minimize Fibrosis During Radiation Therapy.

Advances in wound care| PubMed ID: 34074152

2022
Striae Distensae: Scars without Wounds.

Plastic and reconstructive surgery| PubMed ID: 34181606

2021
2022
2021
2021
2022
2021
The role of Wnt signaling in skin fibrosis.

Medicinal research reviews| PubMed ID: 34431110

2022
2022
Understanding Scarring in the Oral Mucosa.

Advances in wound care| PubMed ID: 34470520

2022
2022
2021
2021
2022
2022
2022
Discussion: Overcoming the Patent Gap: A Guide to Patenting for Plastic Surgeons.

Plastic and reconstructive surgery| PubMed ID: 34550949

2021
2021
Angiogenic CD34+CD146+ adipose-derived stromal cells augment recovery of soft tissue after radiotherapy.

Journal of tissue engineering and regenerative medicine| PubMed ID: 34582109

2021
2021
Integrated spatial multiomics reveals fibroblast fate during tissue repair.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 34620713

2021
2021
2021
2022
2022
2022
2022
Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 35384131

2022
2022
Beyond the Scar: A Basic Science Review of Wound Remodeling.

Advances in wound care| PubMed ID: 35658581

2023
2020
2022
2022
2023
2022
Machine Learning in Tissue Engineering.

Tissue engineering. Part A| PubMed ID: 35943870

2023
2022
2022
2022
2023
Topical vanadate improves tensile strength and alters collagen organisation of excisional wounds in a mouse model.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society| PubMed ID: 36484112

2023
2023
2022
2022
2023
2023
2023
2023
A Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue.

Arteriosclerosis, thrombosis, and vascular biology| PubMed ID: 37051932

2023
2023
2023
Emerging frontiers in regenerative medicine.

Science (New York, N.Y.)| PubMed ID: 37228215

2023
2023
Reduction of Tendon Fibrosis Using Galectin-3 Inhibitors.

Plastic and reconstructive surgery| PubMed ID: 37344932

2023
2023
2023
2023
2023
2023
A Review of Radiation-Induced Vascular Injury and Clinical Impact.

Annals of plastic surgery| PubMed ID: 37962260

2024
2024
2024
Understanding wound healing in obesity.

World journal of experimental medicine| PubMed ID: 38590299

2024
2024
2024
2024
2024
Role of ferroptosis in radiation-induced soft tissue injury.

Cell death discovery| PubMed ID: 38969638

2024
2024
2024
2024
2024
Clinical, mechanistic, and therapeutic landscape of cutaneous fibrosis.

Science translational medicine| PubMed ID: 39321265

2024
Modelling and targeting mechanical forces in organ fibrosis.

Nature reviews bioengineering| PubMed ID: 39552705

2024
2024
The DERMIS Study: Methodologies, Results, and Implications for the Future.

Journal of diabetes science and technology| PubMed ID: 39633523

2024
Endothelial-specific CXCL12 regulates neovascularization during tissue repair and tumor progression.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 39698751

2024
2025
2025
2025
2025
2025
2025
Osteopontin attenuates the foreign-body response to silicone implants.

Nature biomedical engineering| PubMed ID: 40128393

2025
2025
2025
2025
2025
2025
2025
2025
2025
2025
2025
The Unique Roles of Adipose Tissue in Wound Healing.

Advances in wound care| PubMed ID: 41027673

2025
2025
2025
2025
The Challenge of Healing Wounds in Radiation-Injured Skin.

Advances in wound care| PubMed ID: 41313654

2025
A Developmental Roadmap Toward Abdominal Adhesions Prevention Technologies.

Annals of surgery open : perspectives of surgical history, education, and clinical approaches| PubMed ID: 41451177

2025
2026
2026
2026
2026
Understanding and Advancing Wound Healing in the Era of Multi-Omic Technology.

Bioengineering (Basel, Switzerland)| PubMed ID: 41595988

2025
2026
2026
2026