Nina Bhardwaj

Cancer Institute, NYU Langone Medical Center

Affiliated withNYU Langone Medical Center Mount Sinai Medical Center

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 20	2013
Publication title Cited by 7	2014

Other Publications

Article	Year
Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection. Journal of virology\| PubMed ID: 11739706	2002
Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cells. AIDS (London, England)\| PubMed ID: 11807300	2002
Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses. Current opinion in immunology\| PubMed ID: 12088682	2002
Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection. Journal of virology\| PubMed ID: 12097565	2002
Activation of HIV-1 specific CD4 and CD8 T cells by human dendritic cells: roles for cross-presentation and non-infectious HIV-1 virus. AIDS (London, England)\| PubMed ID: 12131208	2002
Dendritic cell amplification of HIV type 1-specific CD8+ T cell responses in exposed, seronegative heterosexual women. AIDS research and human retroviruses\| PubMed ID: 12167272	2002
A division of labor: DC subsets and HIV receptor diversity. Nature immunology\| PubMed ID: 12352961	2002
A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: implications for immunotherapy. Vaccine\| PubMed ID: 12477423	2002
Activation of influenza virus-specific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity. Blood\| PubMed ID: 12511409	2003
Immunotherapy for AIDS virus infections: cautious optimism for cell-based vaccine. Nature medicine\| PubMed ID: 12514710	2003
Dominant effector memory characteristics, capacity for dynamic adaptive expansion, and sex bias in the innate Valpha24 NKT cell compartment. European journal of immunology\| PubMed ID: 12616479	2003
Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells. Blood\| PubMed ID: 12933572	2003
Against the self: dendritic cells versus cancer. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica\| PubMed ID: 12974782	2003
Type I interferons promote cross-priming: more functions for old cytokines. Nature immunology\| PubMed ID: 14515123	2003
Dendritic cells and the promise of therapeutic vaccines for human immunodeficiency virus (HIV)-1. Current HIV research\| PubMed ID: 15043203	2003
Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells. Journal of virology\| PubMed ID: 15113904	2004
DC-virus interplay: a double edged sword. Seminars in immunology\| PubMed ID: 15130499	2004
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. Journal of virology\| PubMed ID: 15163708	2004
Danger signals: a time and space continuum. Trends in molecular medicine\| PubMed ID: 15177188	2004
Manipulating dendritic cell biology for the active immunotherapy of cancer. Blood\| PubMed ID: 15231572	2004
Maturation matters: importance of maturation for antitumor immunity of dendritic cell vaccines. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 15365084	2004
Exploiting dendritic cells for active immunotherapy of cancer and chronic infection. Methods in molecular medicine\| PubMed ID: 15585909	2005
Generation of autologous peptide- and protein-pulsed dendritic cells for patient-specific immunotherapy. Methods in molecular medicine\| PubMed ID: 15585916	2005
Plasmacytoid dendritic cells: linking innate and adaptive immunity. Journal of virology\| PubMed ID: 15596797	2005
CD8 epitope escape and reversion in acute HCV infection. The Journal of experimental medicine\| PubMed ID: 15611288	2004
The cancer-testis antigens CT7 (MAGE-C1) and MAGE-A3/6 are commonly expressed in multiple myeloma and correlate with plasma-cell proliferation. Blood\| PubMed ID: 15761016	2005
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. The Journal of experimental medicine\| PubMed ID: 15781581	2005
Recent advances in dendritic cell biology. Journal of clinical immunology\| PubMed ID: 15821885	2005
Recent advances in dendritic cell biology. Journal of clinical immunology\| PubMed ID: 16118915	2005
Combining radiotherapy and immunotherapy: a revived partnership. International journal of radiation oncology, biology, physics\| PubMed ID: 16199306	2005
Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions. The Journal of clinical investigation\| PubMed ID: 16224540	2005
Expansion of HIV-specific CD4+ and CD8+ T cells by dendritic cells transfected with mRNA encoding cytoplasm- or lysosome-targeted Nef. Blood\| PubMed ID: 16249391	2006
The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood\| PubMed ID: 16614246	2006
Clinical relevance of neutral endopeptidase (NEP/CD10) in melanoma. Journal of translational medicine\| PubMed ID: 17207277	2007
Harnessing the immune system to treat cancer. The Journal of clinical investigation\| PubMed ID: 17476342	2007
Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17517626	2007
Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1. European journal of immunology\| PubMed ID: 17534864	2007
Armed and ready: how effector T cells deploy in reactive lymph nodes to modulate immunity. Nature immunology\| PubMed ID: 17579644	2007
Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors. Cancer immunity\| PubMed ID: 17625806	2007
Exploiting dendritic cells for active immunotherapy of cancer and chronic infections. Molecular biotechnology\| PubMed ID: 17914192	2007
Lack of functionally active Melan-A(26-35)-specific T cells in the blood of HLA-A2+ vitiligo patients. The Journal of investigative dermatology\| PubMed ID: 18337837	2008
Differentiation of peripheral blood monocytes into dendritic cells. Current protocols in immunology / edited by John E. Coligan ... [et al.]\| PubMed ID: 18432951	2005
Quantitative effect of suboptimal codon usage on translational efficiency of mRNA encoding HIV-1 gag in intact T cells. PloS one\| PubMed ID: 18523584	2008
The anergic state in sarcoidosis is associated with diminished dendritic cell function. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18566441	2008
Immunization of malignant melanoma patients with full-length NY-ESO-1 protein using TLR7 agonist imiquimod as vaccine adjuvant. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18566444	2008
HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism. The Journal of clinical investigation\| PubMed ID: 18776940	2008
Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells. Cancer research\| PubMed ID: 19010919	2008
KBMA Listeria monocytogenes is an effective vector for DC-mediated induction of antitumor immunity. The Journal of clinical investigation\| PubMed ID: 19033668	2008
Efficient in vitro expansion of JC virus-specific CD8(+) T-cell responses by JCV peptide-stimulated dendritic cells from patients with progressive multifocal leukoencephalopathy. Virology\| PubMed ID: 19062062	2009
HLA class I - associated immunodominance affects CTL responsiveness to an ESO recombinant protein tumor antigen vaccine. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19118058	2009
In vitro priming recapitulates in vivo HIV-1 specific T cell responses, revealing rapid loss of virus reactive CD4 T cells in acute HIV-1 infection. PloS one\| PubMed ID: 19165342	2009
Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19188590	2009
Vaccination with a recombinant protein encoding the tumor-specific antigen NY-ESO-1 elicits an A2/157-165-specific CTL repertoire structurally distinct and of reduced tumor reactivity than t... Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 19238015	2009
Phosphorylated 4E-BP1 is associated with poor survival in melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19336517	2009
Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection. Current opinion in HIV and AIDS\| PubMed ID: 19372886	2007
Innate immune responses in primary HIV-1 infection. Current opinion in HIV and AIDS\| PubMed ID: 19372942	2008
Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19414772	2009
A randomized therapeutic vaccine trial of canarypox-HIV-pulsed dendritic cells vs. canarypox-HIV alone in HIV-1-infected patients on antiretroviral therapy. Vaccine\| PubMed ID: 19450647	2009
Vaccination with recombinant NY-ESO-1 protein elicits immunodominant HLA-DR52b-restricted CD4+ T cell responses with a conserved T cell receptor repertoire. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19531622	2009
Dendritic cells as targets for therapy in rheumatoid arthritis. Nature reviews. Rheumatology\| PubMed ID: 19798032	2009
Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19915147	2009
Resolution of immune activation defines nonpathogenic SIV infection. The Journal of clinical investigation\| PubMed ID: 19959871	2009
Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research. American journal of translational research\| PubMed ID: 19966936	2009
Cellular immune responses against CT7 (MAGE-C1) and humoral responses against other cancer-testis antigens in multiple myeloma patients. Cancer immunity\| PubMed ID: 20108890	2010
HIV-1 impairs in vitro priming of naÃ¯ve T cells and gives rise to contact-dependent suppressor T cells. European journal of immunology\| PubMed ID: 20455275	2010
Directing dendritic cell immunotherapy towards successful cancer treatment. Immunotherapy\| PubMed ID: 20473346	2010
CD8+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells. PloS one\| PubMed ID: 20585396	2010
A needle in the 'cancer vaccine' haystack. Nature medicine\| PubMed ID: 20689546	2010
Evidence of dysregulation of dendritic cells in primary HIV infection. Blood\| PubMed ID: 20693428	2010
Toll-like receptor agonists: are they good adjuvants? Cancer journal (Sudbury, Mass.)\| PubMed ID: 20693851	2010
LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression. The Journal of clinical investigation\| PubMed ID: 21041949	2010
Oligonucleotide motifs that disappear during the evolution of influenza virus in humans increase alpha interferon secretion by plasmacytoid dendritic cells. Journal of virology\| PubMed ID: 21307198	2011
Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-Î±-producing and partially matured phenotype. The Journal of clinical investigation\| PubMed ID: 21339641	2011
DCs and NK cells: critical effectors in the immune response to HIV-1. Nature reviews. Immunology\| PubMed ID: 21350578	2011
Matrix metalloproteinase-2 conditions human dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and OX40L-dependent pathway. Cancer cell\| PubMed ID: 21397857	2011
CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases. Cancer immunology, immunotherapy : CII\| PubMed ID: 21465316	2011
Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells. Journal of virology\| PubMed ID: 21507971	2011
MAGE-A inhibits apoptosis in proliferating myeloma cells through repression of Bax and maintenance of survivin. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21565982	2011
TLR4 engagement during TLR3-induced proinflammatory signaling in dendritic cells promotes IL-10-mediated suppression of antitumor immunity. Cancer research\| PubMed ID: 21730023	2011
miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. Cancer cell\| PubMed ID: 21741600	2011
Plasmacytoid dendritic cells lead the charge against tumors. The Journal of clinical investigation\| PubMed ID: 22251700	2012
Immune response in melanoma: an in-depth analysis of the primary tumor and corresponding sentinel lymph node. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 22425909	2012
Dysregulation of anti-tumor immunity by the matrix metalloproteinase-2. Oncoimmunology\| PubMed ID: 22720227	2012
Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 22767669	2012
Activation of the noncanonical NF-ÎºB pathway by HIV controls a dendritic cell immunoregulatory phenotype. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22879398	2012
Plasma factors during chronic HIV-1 infection impair IL-12 secretion by myeloid dendritic cells via a virus-independent pathway. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 22902724	2012
Plasmacytoid dendritic cells in HIV infection. Advances in experimental medicine and biology\| PubMed ID: 22975872	2013
HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44. The Journal of clinical investigation\| PubMed ID: 23160198	2012
Inhibition of both BRAF and MEK in BRAF(V600E) mutant melanoma restores compromised dendritic cell (DC) function while having differential direct effects on DC properties. Cancer immunology, immunotherapy : CII\| PubMed ID: 23306863	2013
Aspirin Attenuates Platelet Activation and Immune Activation in HIV-1-Infected Subjects on Antiretroviral Therapy: A Pilot Study. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 23406976	2013
Influenza, but not HIV-specific CTL epitopes, elicits delayed-type hypersensitivity (DTH) reactions in HIV-infected patients. European journal of immunology\| PubMed ID: 23504637	2013
Phenotypic properties of transmitted founder HIV-1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23542380	2013
Antigen depots: T cell traps? Nature medicine\| PubMed ID: 23558621	2013
Dendritic cell immunotherapy. Annals of the New York Academy of Sciences\| PubMed ID: 23651191	2013
Dendritic cell dysregulation during HIV-1 infection. Immunological reviews\| PubMed ID: 23772620	2013
Active systemic lupus erythematosus is associated with decreased blood conventional dendritic cells. Experimental and molecular pathology\| PubMed ID: 23773850	2013
HIV type 1 infection of plasmacytoid and myeloid dendritic cells is restricted by high levels of SAMHD1 and cannot be counteracted by Vpx. AIDS research and human retroviruses\| PubMed ID: 23924154	2014
A bloody mess: dendritic cells use hemophagocytosis to regulate viral inflammation. Immunity\| PubMed ID: 24054326	2013
Impact of MAPK Pathway Activation in BRAF(V600) Melanoma on T Cell and Dendritic Cell Function. Frontiers in immunology\| PubMed ID: 24194739	2013
Dendritic cells in progression and pathology of HIV infection. Trends in immunology\| PubMed ID: 24246474	2014
Dendritic Cell-Targeted Approaches to Modulate Immune Dysfunction in the Tumor Microenvironment. Frontiers in immunology\| PubMed ID: 24339825	2013
Dissection of Immune Gene Networks in Primary Melanoma Tumors Critical for Antitumor Surveillance of Patients with Stage II-III Resectable Disease. The Journal of investigative dermatology\| PubMed ID: 24522433	2014
Reversal of NK-Cell Exhaustion in Advanced Melanoma by Tim-3 Blockade. Cancer immunology research\| PubMed ID: 24795354	2014
Therapeutic In-Situ Autovaccination against Solid Cancers with Intratumoral Poly-ICLC: Case report, Hypothesis, and Clinical Trial. Cancer immunology research\| PubMed ID: 24801836	2014