Xiaoke Yin

National Heart and Lung Institute, Imperial College London

Affiliated withImperial College London King's College London

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2026
Publication title Cited by 30	2017

Other Publications

Article	Year
Vascular proteomics: linking proteomic and metabolomic changes. Proteomics\| PubMed ID: 15540213	2004
Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16123314	2005
Proteomic dataset of Sca-1+ progenitor cells. Proteomics\| PubMed ID: 16240289	2005
Proteomic dataset of mouse aortic smooth muscle cells. Proteomics\| PubMed ID: 16240290	2005
Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells. Proteomics\| PubMed ID: 17163435	2006
Protein kinase D selectively targets cardiac troponin I and regulates myofilament Ca2+ sensitivity in ventricular myocytes. Circulation research\| PubMed ID: 17322173	2007
Integrated membrane protein analysis of mature and embryonic stem cell-derived smooth muscle cells using a novel combination of CyDye/biotin labeling. Molecular & cellular proteomics : MCP\| PubMed ID: 17627936	2007
Combined metabolomic and proteomic analysis of human atrial fibrillation. Journal of the American College of Cardiology\| PubMed ID: 18237690	2008
Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice. Circulation research\| PubMed ID: 18388323	2008
Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures. Circulation research\| PubMed ID: 19023133	2009
Identification of cardiac myosin-binding protein C as a candidate biomarker of myocardial infarction by proteomics analysis. Molecular & cellular proteomics : MCP\| PubMed ID: 19721077	2009
Proteomic analysis of the secretome of human umbilical vein endothelial cells using a combination of free-flow electrophoresis and nanoflow LC-MS/MS. Proteomics\| PubMed ID: 19810032	2009
Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques. Circulation. Cardiovascular genetics\| PubMed ID: 20031610	2009
Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution. Molecular & cellular proteomics : MCP\| PubMed ID: 20037178	2010
Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin. Circulation research\| PubMed ID: 20224040	2010
Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism. Circulation research\| PubMed ID: 20489163	2010
Proteomics characterization of extracellular space components in the human aorta. Molecular & cellular proteomics : MCP\| PubMed ID: 20551380	2010
Proteomic characterization of human early pro-angiogenic cells. Journal of molecular and cellular cardiology\| PubMed ID: 21147123	2011
Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome. Journal of molecular and cellular cardiology\| PubMed ID: 21354174	2011
Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach. Molecular & cellular proteomics : MCP\| PubMed ID: 21593211	2011
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas. BMC cancer\| PubMed ID: 21612605	2011
Chromobox protein homolog 3 is essential for stem cell differentiation to smooth muscles in vitro and in embryonic arteriogenesis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 21659642	2011
Substrate modifications precede the development of atrial fibrillation after cardiac surgery: a proteomic study. The Annals of thoracic surgery\| PubMed ID: 21718835	2011
Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue. Circulation research\| PubMed ID: 21921264	2011
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury. Circulation\| PubMed ID: 22261194	2012
Method for protein subfractionation of cardiovascular tissues before DIGE analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22311768	2012
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nature cell biology\| PubMed ID: 22327366	2012
Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes. Blood\| PubMed ID: 22665935	2012
Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions. Circulation research\| PubMed ID: 23071158	2013
Proteomics: from single molecules to biological pathways. Cardiovascular research\| PubMed ID: 23180722	2013
Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques. Basic research in cardiology\| PubMed ID: 23224081	2013
Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. Journal of molecular and cellular cardiology\| PubMed ID: 23277191	2013
Glycoproteomic analysis of the secretome of human endothelial cells. Molecular & cellular proteomics : MCP\| PubMed ID: 23345538	2013
A sequential extraction methodology for cardiac extracellular matrix prior to proteomics analysis. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23606260	2013
Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties. Molecular & cellular proteomics : MCP\| PubMed ID: 23660474	2013
Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation\| PubMed ID: 23956210	2013
Gestational diabetes mellitus impairs Nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero. Diabetes\| PubMed ID: 23974919	2013
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circulation research\| PubMed ID: 24006456	2013
The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation. Cell metabolism\| PubMed ID: 24011070	2013
Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2. The Journal of biological chemistry\| PubMed ID: 24045946	2013
Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 24158518	2014
Gene network and proteomic analyses of cardiac responses to pathological and physiological stress. Circulation. Cardiovascular genetics\| PubMed ID: 24214729	2013
Over-expression of HSP47 augments mouse embryonic stem cell smooth muscle differentiation and chemotaxis. PloS one\| PubMed ID: 24454956	2014
Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. The Journal of clinical investigation\| PubMed ID: 24743145	2014
Redox state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis. Molecular & cellular proteomics : MCP\| PubMed ID: 24958171	2014
Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice. EMBO molecular medicine\| PubMed ID: 25038053	2014
Role of miR-195 in aortic aneurysmal disease. Circulation research\| PubMed ID: 25201911	2014
Vascular smooth muscle cell calcification is mediated by regulated exosome secretion. Circulation research\| PubMed ID: 25711438	2015
ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1. Circulation\| PubMed ID: 25712208	2015
Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart. Lancet (London, England)\| PubMed ID: 26312895	2015
XBP 1-Deficiency Abrogates Neointimal Lesion of Injured Vessels Via Cross Talk With the PDGF Signaling. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26315405	2015
Angiogenic microRNAs Linked to Incidence and Progression of Diabetic Retinopathy in Type 1 Diabetes. Diabetes\| PubMed ID: 26395742	2016
Association of MicroRNAs and YRNAs With Platelet Function. Circulation research\| PubMed ID: 26646931	2016
"Young at heart": Regenerative potential linked to immature cardiac phenotypes. Journal of molecular and cellular cardiology\| PubMed ID: 26827899	2016
Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 27034473	2016
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins. Cardiovascular research\| PubMed ID: 27068509	2016
Chronic miR-29 antagonism promotes favorable plaque remodeling in atherosclerotic mice. EMBO molecular medicine\| PubMed ID: 27137489	2016
Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms. Amino acids\| PubMed ID: 27143170	2016
Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase-1 in vascular endothelial growth factor-mediated angiogenesis. Scientific reports\| PubMed ID: 27388959	2016
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Circulation\| PubMed ID: 27559042	2016
Systems biology-opportunities and challenges: the application of proteomics to study the cardiovascular extracellular matrix. Cardiovascular research\| PubMed ID: 27635058	2016
Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes. Diabetes\| PubMed ID: 27899485	2017
Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin. Scientific reports\| PubMed ID: 28045034	2017
Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III. Journal of the American College of Cardiology\| PubMed ID: 28209220	2017
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. The Journal of clinical investigation\| PubMed ID: 28319050	2017