IL

Irving L. Weissman

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine

Affiliated withStanford University School of MedicineStanford University

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2
Year
Parabiosis in Mice: A Detailed Protocol
Publication title

Cited by 175

2013
2014

Other Publications

Article
Year
Evolution of a protochordate allorecognition locus.

Science (New York, N.Y.)| PubMed ID: 14963321

2004
Plasticity of adult stem cells.

Cell| PubMed ID: 15006347

2004
2004
2004
2004
2004
2004
2004
2004
2004
2005
2004
2004
2004
2005
2005
2005
Cancer stem cells in solid tumors.

Current opinion in biotechnology| PubMed ID: 18023337

2007
Enforced Bcl-2 expression overrides serum and feeder cell requirements for mouse embryonic stem cell self-renewal.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15728354

2005
2004
2005
Hematopoietic cells maintain hematopoietic fates upon entering the brain.

The Journal of experimental medicine| PubMed ID: 15897275

2005
Cell intrinsic alterations underlie hematopoietic stem cell aging.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 15967997

2005
Identification of mast cell progenitors in adult mice.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16006518

2005
2005
Normal and neoplastic stem cells.

Novartis Foundation symposium| PubMed ID: 16050249

2005
2005
2006
2005
2005
Identification of a novel gene involved in asexual organogenesis in the budding ascidian Botryllus schlosseri.

Developmental dynamics : an official publication of the American Association of Anatomists| PubMed ID: 16193502

2005
2006
2005
2005
2006
2005
2006
Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16407117

2006
Medicine: politic stem cells.

Nature| PubMed ID: 16407938

2006
2006
Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16492737

2006
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16603627

2006
2006
2006
A cell-surface molecule involved in organ-specific homing of lymphocytes. 1983.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 16785489

2006
2006
2006
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell.

The American journal of pathology| PubMed ID: 16877336

2006
2006
2006
The cancer stem cell hypothesis: a work in progress.

Laboratory investigation; a journal of technical methods and pathology| PubMed ID: 17075578

2006
Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17098862

2006
2006
2007
2007
2007
Hematopoietic stem cell aging: mechanism and consequence.

Experimental gerontology| PubMed ID: 17275237

2007
Striving for normality: whole body regeneration through a series of abnormal generations.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 17289924

2007
2007
2007
2007
2007
2007
CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17576927

2007
2007
Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17640912

2007
Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17640913

2007
2007
2007
2008
Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation.

Journal of immunology (Baltimore, Md. : 1950)| PubMed ID: 17982071

2007
2007
2007
2008
2008
2008
2007
2007
2008
Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18443294

2008
Generation of a monoclonal antibody library against human embryonic stem cells.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 18453249

2007
2008
2009
The E. Donnall Thomas lecture: normal and neoplastic stem cells.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 18640567

2008
Space-time considerations for hematopoietic stem cell transplantation.

European journal of immunology| PubMed ID: 18651698

2008
Hematopoietic stem cells and the aging hematopoietic system.

Seminars in hematology| PubMed ID: 18809091

2008
2009
2008
2008
2008
2008
2008
Wnt-mediated self-renewal of neural stem/progenitor cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18957545

2008
2009
In vivo serial evaluation of superparamagnetic iron-oxide labeled stem cells by off-resonance positive contrast.

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine| PubMed ID: 19030159

2008
Cancer stem cell-directed therapies: recent data from the laboratory and clinic.

Molecular therapy : the journal of the American Society of Gene Therapy| PubMed ID: 19066601

2009
2009
2009
Two-step oligoclonal development of male germ cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19098099

2009
2008
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19181846

2009
2009
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19218430

2009
2008
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19237556

2009
2009
2009
Expression of AA4.1 marks lymphohematopoietic progenitors in early mouse development.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19458045

2009
Manganese-guided cellular MRI of human embryonic stem cell and human bone marrow stromal cell viability.

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine| PubMed ID: 19526508

2009
2009
2009
2009
2009
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 19666525

2009
2009
Hematopoietic stem and progenitor cells and the inflammatory response.

Annals of the New York Academy of Sciences| PubMed ID: 19769744

2009
2009
2009
Niche recycling through division-independent egress of hematopoietic stem cells.

The Journal of experimental medicine| PubMed ID: 19887396

2009
2009
2009
2010
2010
MiDReG: a method of mining developmentally regulated genes using Boolean implications.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20231483

2010
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20304793

2010
2010
2010
Macrophages as mediators of tumor immunosurveillance.

Trends in immunology| PubMed ID: 20452821

2010
Purified hematopoietic stem cell transplantation: the next generation of blood and immune replacement.

Immunology and allergy clinics of North America| PubMed ID: 20493393

2010
2010
2010
2010
2010
The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies.

The International journal of developmental biology| PubMed ID: 20711980

2010
2010
2010
Hematopoietic stem cell: self-renewal versus differentiation.

Wiley interdisciplinary reviews. Systems biology and medicine| PubMed ID: 20890962

2010
Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease?

Vascular medicine (London, England)| PubMed ID: 20926497

2010
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 20956329

2010
MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21118986

2010
2011
2011
2011
2010
VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21233420

2011
2011
2011
50 years later: remembering the paper.

Radiation research| PubMed ID: 21268706

2011
Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21300885

2011
2012
2011
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21368213

2011
Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21383193

2011
Long-term outcome of patients with metastatic breast cancer treated with high-dose chemotherapy and transplantation of purified autologous hematopoietic stem cells.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation| PubMed ID: 21767515

2012
2011
Enhanced survival of pluripotent stem cells under stressful conditions.

Cell cycle (Georgetown, Tex.)| PubMed ID: 21791974

2011
2011
2011
2011
2011
2011
2011
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22123971

2011
2012
2012
Three differentiation states risk-stratify bladder cancer into distinct subtypes.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22308455

2012
2012
2012
The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22451913

2012
Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 22451919

2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
In vivo directed differentiation of pluripotent stem cells for skeletal regeneration.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23169671

2012
2012
E. Donnall Thomas (1920-2012).

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23197829

2012
2013
Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23382202

2013
Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23388639

2013
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23391730

2013
2013
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23690610

2013
2013
2013
2013
2013
Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23858471

2013
Identification of a colonial chordate histocompatibility gene.

Science (New York, N.Y.)| PubMed ID: 23888037

2013
2013
2013
2013
2013
2013
2013