Jian Hu
Department of Cancer Biology, UT MD Anderson Cancer Center
Affiliated withUT MD Anderson Cancer CenterSanofi Pasteur LimitedThe Traditional Chinese Medicine Hospital of Beichuan Qiang Autonomous County
Research Area
Biography
Jiancheng Hu is a Principal Investigator in the Division of Cellular and Molecular Research, National Cancer Centre Singapore, and an Asistant Professor in the Cancer and Stem Cell Program, Duke-NUS Medical School, Singapore. He received his B.S. in 1996 from the East China University of Science and Technology, M.S. in 2001 from Peking University, China , and Ph.D. in 2007 from University of Colorado, USA.
During Dr Hu’s training, he developed a keen interest on cell signaling. As a postdoctoral fellow in Andrey Shaw’s lab at Washington University in Saint Louis and Howard Hughes Medical Institute (2008~2014), USA, he studied the molecular mechanism(s) that regulates the Ras/RAF/MEK/ERK signaling and how this signaling pathway was aberrantly activated in cancer and developmental diseases. In 2014, He was recruited to National Cancer Centre Singapore as a Pricinpal Investigator and Duke-NUS Medical School as an assistant professor.
Dr Hu’s research focuses on: (1) the regulatory mechanism of RAF/MEK/ERK kinase cascade and other oncogenic protein kinases; (2) the molecular basis that underlie Intrinsic and acquired resistance of kinase inhibitors in cancer therapy; (3) the development of novel protein kinase inhibitors for cancer treatment.
JoVE Journal Publications
Article Total : 3 | Year |
|---|---|
 Publication title Cited by 3 | 2015 |
 Publication title Cited by 117 | 2017 |
 Publication title Cited by 1 | 2024 |