Trichoderma Harzianum

Trichoderma harzianum is a filamentous soil fungus widely studied for its ability to support plant health and produce valuable bioproducts. As a biological control agent, it colonizes roots and surrounding substrates, competes with pathogenic fungi, attacks them through mycoparasitism, and secretes cell-wall-degrading enzymes and antimicrobial compounds; it can also stimulate plant defense responses. In bioengineering, T. harzianum serves as a platform for developing sustainable biopesticides, enzyme production systems, and microbial formulations that reduce dependence on synthetic chemicals. Characterizing its genetics, fermentation behavior, and host interactions helps improve strain performance and adapt fungal technologies to agriculture and other industrial settings.

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Research

JoVE Journal - Environment

Expression of Recombinant Cellulase Cel5A from Trichoderma reesei in Tobacco Plants

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2014

Tobacco plants were used to produce a fungal cellulase, TrCel5A, via a transient expression system. The expression could be monitored using a fluorescent fusion protein, and the protein activity was characterized post-expression.

Viability Assay of Trichoderma stromaticum Conidia Inside Human Peripheral Blood Mononuclear-Derived Macrophages

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Cited by 1 •

2023

The technique involving the phagocytosis of fungal conidia by macrophages is widely used for studies evaluating the modulation of the immune responses against fungi. The purpose of this manuscript is to present a method for evaluating the phagocytosis and clearance abilities of human peripheral blood mononuclear-derived macrophages stimulated with Trichoderma stromaticum conidia.

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