Hydrochloric Acid

Hydrochloric acid is a strong, highly corrosive acid formed when hydrogen chloride dissolves in water, and it plays important roles in chemistry and biology. In the stomach, specialized parietal cells secrete hydrogen ions and chloride ions into the gastric lumen, where they combine to produce hydrochloric acid and create a very low pH. This acidic environment helps denature dietary proteins, activate pepsin from its precursor pepsinogen, and limit the survival of many ingested microorganisms. Studying hydrochloric acid supports understanding of digestion, gastric diseases, acid regulation, and the protective mechanisms that prevent damage to stomach tissues.

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JoVE Core - Chemistry

Mixtures of Acids

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2020

The pH of a solution containing an acid can be determined using its acid dissociation constant and its initial concentration. If a solution contains two different acids, then its pH can be determined using one of several methods depending upon the relative strength of the acids and their dissociation constants. A Mixture of a Strong Acid and a Weak Acid In a mixture of a strong acid and a weak acid, the strong acid dissociates completely and becomes a source of almost all the hydronium ions...

Acid Strength and Molecular Structure

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2020

Binary Acids and Bases In the absence of any leveling effect, the acid strength of binary compounds of hydrogen with nonmetals (A) increases as the H-A bond strength decreases down a group in the periodic table. For group 17, the order of increasing acidity is HF < HCl < HBr < HI. Likewise, for group 16, the order of increasing acid strength is H2O < H2S < H2Se < H2Te. Across a row in the periodic table, the acid strength of binary hydrogen compounds increases with increasing...

Acids, Bases and Neutralization Reactions

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2020

An acid-base reaction is one in which a hydrogen ion, H+, is transferred from one chemical species to another. Such reactions are of central importance to numerous natural and technological processes, ranging from the chemical transformations within cells or lakes and oceans to the industrial-scale production of fertilizers, pharmaceuticals, and other substances essential to the society. There are several ways of defining an acid. In the context of aqueous solutions, an acid is a substance...

Ions as Acids and Bases

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2020

Salts with Acidic Ions Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation: The ammonium ion is the conjugate acid of the base ammonia,...

Bronsted-Lowry Acids and Bases

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2020

The acid-base reaction class has been studied for quite some time. In 1680, Robert Boyle reported traits of acid solutions that included their ability to dissolve many substances, to change the colors of certain natural dyes, and to lose these traits after coming in contact with alkali (base) solutions. In the eighteenth century, it was recognized that acids have a sour taste, react with limestone to liberate a gaseous substance (now known to be CO2), and interact with alkalis to form neutral...

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