Intrauterine Devices
Intrauterine Devices - Related Videos
07:03
Intrauterine Telemetry to Measure Mouse Contractile Pressure In Vivo
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Cited by 16 •
2015
This manuscript provides a protocol for implanting telemeters in the mouse for the purpose of measuring intrauterine pressures during pregnancy.
11:44
Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
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Cited by 1 •
2025
Intrauterine adhesions (IUAs), the most common pathological consequence of endometrial injury, severely impair reproductive function. Trauma and infection are widely recognized as key risk factors for IUA development. We have successfully established a reproducible rat model of IUAs by combining two critical injury methods: mechanical curettage and infectious induction with lipopolysaccharide.
01:21
Intrauterine Drug Delivery Systems
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2026
Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
08:29
Thermal Measurement Techniques in Analytical Microfluidic Devices
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Cited by 6 •
2015
Here, we present three protocols for thermal measurements in microfluidic devices.
14:19
Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
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Cited by 11 •
2013
We describe examination of fetal cardiac function with contemporary functional fetal echocardiography and fetoplacental Doppler ultrasound using the VisualSonics VEVO 2100 microultrasound in a surgically induced model of intrauterine fetal growth restriction in a rabbit.
FAQs
Copper ions alter the local reproductive environment in ways that impair sperm motility and viability. Motility is the ability of sperm to move, while viability refers to remaining biologically functional. Reducing both properties limits sperm’s ability to participate in the reproductive process, providing the biological basis for copper-mediated contraception.
Levonorgestrel changes more than one reproductive condition. It thickens cervical mucus, creating a barrier that restricts sperm movement, and it can also suppress sperm movement directly. In addition, hormonal effects thin the uterine lining. Together, these changes show how one released hormone can influence cervical, sperm-related, and uterine factors.
These targets represent different biological points at which pregnancy can be prevented. Sperm must remain functional and move effectively, while the uterus provides the lining involved in reproductive processes. Copper-based effects emphasize sperm function, whereas hormonal effects combine altered mucus, reduced sperm movement, and a thinner uterine lining.
Reversibility means that the device can be removed when pregnancy is desired rather than serving as a permanent contraceptive intervention. This feature connects a temporary change in reproductive conditions with future fertility planning. In clinical care, placement and later removal allow contraception to be used during one period without permanently preventing a later attempt at pregnancy.
Their long-acting design provides contraception without requiring a daily action. That characteristic distinguishes them from approaches that depend on repeated day-to-day use and makes them relevant to reproductive-health planning over extended periods. The device remains an ongoing contraceptive option until removal, supporting a less routine-dependent approach to pregnancy prevention.
IUDs provide a practical biology example because their effects involve several reproductive components at once. Copper ions and levonorgestrel influence sperm-related functions, cervical mucus, and the uterine lining, while the device is placed in the uterus. Studying these interactions helps connect reproductive anatomy with hormones, gametes, and fertility in clinical care.