Oropharynx

The oropharynx is the middle portion of the pharynx, located behind the oral cavity, and serves as a shared passage for air, food, and liquids. It extends from the soft palate to the level of the hyoid bone and includes structures such as the tongue base, palatine tonsils, and posterior pharyngeal wall. During swallowing, coordinated muscle contractions move material through the oropharynx while protective reflexes help prevent entry into the airway; during breathing, it conducts air toward the larynx. Understanding oropharyngeal anatomy supports the study of digestion, respiration, immune defense, swallowing disorders, sleep-related airway obstruction, and infections.

Oropharynx - Related Videos

Research

JoVE EoE - Bacterial Pathogenesis and Host Interactions

Preparation of a Murine Oropharyngeal Aspiration Model to Establish Bacterial Lung Infections

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2026

Source: Nielsen, T. B., et al., Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia. J. Vis. Exp. (2018)This video demonstrates the procedure of delivering bacteria through the oropharynx into the lungs of an anesthetized mouse to induce lung infection and trigger an immune response.

Murine Left Anterior Descending (LAD) Coronary Artery Ligation: An Improved and Simplified Model for Myocardial Infarction

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Cited by 52 •

2017

We provide a reliable method for left anterior descending artery (LAD) ligation in a mouse model. This method is comparatively less invasive than other methods, involving endotracheal intubation, a left-sided thoracotomy approach, and thoracentesis. This method can be used as a model for both acute and chronic myocardial infarction (MI).

Protein Transfection of Mouse Lung

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Cited by 1 •

2013

Transgenic mice or viral vectors have been used to increase protein expression within the lung. However, these techniques are time-consuming, technically challenging and have off-target effects that can confound results. Our protein transfection protocol uses a lipid based transfection reagent and an ultrafine microsprayer to uniformly deliver active protein to lung cells.

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

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2011

We describe a technique to maintain oxygenation and ventilation using an endotracheal tube inserted nasally to the level of the naso-pharynx while sealing the mouth and nares for successful positive pressure ventilation.

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

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Cited by 16 •

2016

The aim of this study was to establish a standardized protocol for sleep endoscopy to differentiate obstruction patterns in obstructive sleep apnea (OSA). Target-controlled infusion (TCI) of the sedative was combined with real-time monitoring of the depth of sedation using bispectral analysis.

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