Postnatal Microbial Succession

Postnatal microbial succession is the stepwise establishment and transformation of microbial communities in an infant after birth, a process that shapes early host development and health. Microorganisms from the birth environment, feeding, caregivers, and surroundings colonize body sites, where changes in oxygen availability, nutrients, pH, immune activity, and microbial competition favor different organisms over time. Studying this progression helps explain how the infant microbiome develops, interacts with the maturing immune system, and responds to factors such as delivery mode, diet, antibiotics, and environment. These insights support research into healthy development, infection risk, disease susceptibility, and strategies for restoring microbial balance.

Postnatal Microbial Succession - Related Videos

Education

JoVE Core - Biology

Ecological Succession

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2026

Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...

Research

JoVE Journal - Behavior
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The Successive Alleys Test of Anxiety in Mice and Rats

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Cited by 49 •

2013

The plus-maze measures anxiety-like behaviour in rodents. There are two opposite closed and two opposite open arms; anxious rodents avoid the open arms. The central area is neither completely open nor closed, so time spent here is ambiguous and difficult to interpret. Here a modification of the plus-maze protocol eliminating this area is described.

Investigating the Microbial Community in the Termite Hindgut - Interview

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2007

Jared Leadbetter explains why the termite-gut microbial community is an excellent system for studying the complex interactions between microbes. The symbiotic relationship existing between the host insect and lignocellulose-degrading gut microbes is explained, as well as the industrial uses of these microbes for degrading plant biomass and generating biofuels.

Research

JoVE Journal - Biology
Free Sample

Biology of Microbial Communities - Interview

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Cited by 3 •

2007

Visualization of Cell Cycle Variations and Determination of Nucleation in Postnatal Cardiomyocytes

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Cited by 5 •

2017

To distinguish cell division from cell cycle variations in cardiomyocytes, we present protocols using two transgenic mouse lines: Myh6-H2B-mCh transgenic mice, for the unequivocal identification of cardiomyocyte nuclei, and CAG-eGFP-anillin mice, for distinguishing cell division from cell cycle variations.

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