Sella Turcica

The sella turcica is a saddle-shaped depression in the sphenoid bone at the base of the skull that houses and protects the pituitary gland, a central regulator of endocrine function. Its bony walls and the overlying diaphragma sellae stabilize the gland, while the nearby optic chiasm and cavernous sinuses create important anatomical relationships; expansion within this confined space can affect vision or cranial nerves. In biology and medicine, the sella turcica serves as a landmark for studying skull development, pituitary anatomy, and hormonal regulation, and it is evaluated with radiography, computed tomography, and magnetic resonance imaging to identify structural abnormalities and pituitary tumors.

Sella Turcica - Related Videos

Research

JoVE Journal - Neuroscience

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Cited by 18 •

2018

The aim of this paper is to describe the different steps of the endoscopic endonasal approach to the sella turcica.

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

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2025

This study proposed an age-adjusted regression modeling using midface and cranial base morphology as a potential tool for preoperative evaluation and individualized surgical planning for children with syndromic craniosynostosis (SC).

Selective Depletion of Microglia from Cerebellar Granule Cell Cultures Using L-leucine Methyl Ester

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Cited by 10 •

2015

Microglia can influence neurons and other glia in culture by various non-cell autonomous mechanisms. Here, we present a protocol to selectively deplete microglia from primary neuronal cultures. This method has the potential to elucidate the role of microglial-neuronal interactions, with implications for neurodegenerative conditions where neuroinflammation is a hallmark feature.

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