Controlled Attenuation Parameter

Controlled Attenuation Parameter (CAP) is a noninvasive measurement of hepatic steatosis, or excess fat in the liver, that helps assess fatty liver disease in clinical practice. During transient elastography, a mechanical vibration generates shear waves while ultrasound signals measure how rapidly their energy weakens as they pass through liver tissue; greater attenuation produces higher CAP values, reported in decibels per meter. Clinicians use CAP alongside liver stiffness measurements, medical history, and laboratory findings to estimate steatosis without biopsy. This approach supports screening, disease monitoring, and treatment assessment, although inflammation, fibrosis, body habitus, and other factors can influence interpretation.

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JoVE Core - Molecular Biology

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Research

JoVE Journal - Behavior
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