Network Topology

Network topology is the physical or logical arrangement of nodes, links, and communication pathways in a computer or engineered network, shaping how devices exchange data and how the system performs. It works by organizing connections into structures such as bus, star, ring, or mesh configurations, while addressing and routing mechanisms determine how information moves between endpoints and how failures affect service. In engineering, topology guides network design, component selection, scalability, maintenance, and fault tolerance. Comparing alternative arrangements helps researchers and practitioners balance cost, transmission efficiency, reliability, redundancy, and ease of troubleshooting across industrial, telecommunications, and digital systems.

Network Topology - Related Videos

Research

JoVE EoE - Immunodiagnostics

Assessing Immunological Synapse Topology through Live-Cell Imaging

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2025

This video demonstrates live-cell imaging of immunological synapse topology, investigating the interactions between T lymphocytes and epithelial cells carrying fluorescent antigens. Fluorescence microscopy reveals red cytoplasm displacement and yellow membrane rings in endothelial cells, indicating the formation of immunological synapses.

Determining Membrane Protein Topology Using Fluorescence Protease Protection (FPP)

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Cited by 18 •

2015

Here, we present a protocol to determine the orientation and topology of integral membrane proteins in living cells. This simple protocol relies on selective protease sensitivity of chimeras between the protein of interest and GFP.

Education

JoVE Core - Molecular Biology

Protein Networks

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2020

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions. These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

Network Covalent Solids

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2020

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds. To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

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2025

This study explores the effects of a configurable soft pneumatic robot on enhancing whole-brain network topology post-stroke. Graph theory analysis indicates significant improvements in clustering coefficient, path length, and global efficiency. Findings highlight the potential of programmable robotic protocols to modulate neuroplasticity and optimize functional recovery in stroke rehabilitation.

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