Polydimethylsiloxane Layer
Polydimethylsiloxane Layer - Related Videos
10:01
Kinetics of Addition Polymerization to Polydimethylsiloxane
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2023
Source: Kerry M. Dooley and Michael G. Benton, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Polymers are molecules consisting of many repeating monomer units that are chemically bonded into long chains. They exhibit a broad range of physical properties, which are affected by their chemical structure, molecular weight and degree of polymerization. The polymer industry manufactures thousands of raw materials used in a broad variety of commercial products.1,2 The...
11:23
Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients
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Cited by 13 •
2017
The control of chemical and oxygen gradients is essential for cell cultures. This paper reports a polydimethylsiloxane-polycarbonate (PDMS-PC) microfluidic device capable of reliably generating combinations of chemical and oxygen gradients for cell migration studies, which can be practically utilized in biological labs without sophisticated instrumentation.
08:23
Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
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Cited by 4 •
2016
We demonstrate a storable, transportable lipid bilayer formation system. A lipid bilayer membrane can be formed within 1 hr with over 80% success rate when a frozen membrane precursor is brought to ambient temperature. This system will reduce laborious processes and expertise associated with ion channels.
03:07
Thin-Layer Chromatography - Concepts
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2020
Chromatography Chromatography is a technique used in organic chemistry to separate compounds in a mixture based on their differences in solubility between two different phases. The concept is similar to liquid-liquid extraction, except in chromatography, the two phases consist of the stationary phase and the mobile phase. The stationary phase is a solid — typically a microscale hydrogel bead — while the mobile phase is a carrier solvent. In traditional chromatography, the stationary phase is...
09:56
Layer-by-layer Collagen Deposition in Microfluidic Devices for Microtissue Stabilization
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Cited by 7 •
2015
The creation of functional microtissues within microfluidic devices requires the stabilization of cell phenotypes by adapting traditional cell culture techniques to the limited spatial dimensions in microdevices. Modification of collagen allows the layer-by-layer deposition of ultrathin collagen assemblies that can stabilize primary cells, such as hepatocytes, as microfluidic tissue models.
FAQs
The cross-linked silicon-oxygen backbone gives the layer elastic behavior while retaining chemical stability. Methyl groups contribute to low surface energy, which helps the material interact differently with surrounding surfaces than many higher-energy coatings. Together, these structural features allow a layer to flex with a device, remain optically transparent, and support protective, sealing, or interface-related functions.
These variables determine how the layer performs and how reliably it functions in a device. Thickness affects the physical scale of the coating or film, while curing conditions influence the resulting elastomer properties. Surface treatment changes how the layer interacts with adjacent materials. Controlling all three is therefore important when engineering fluid control, isolation, sealing, or flexible structures.
Low surface energy affects how the material contacts neighboring surfaces, while its elastic behavior allows it to conform against smooth or irregular geometries. This combination supports seals and interfaces without requiring a rigid, perfectly matched shape. In engineering devices, that behavior can help separate regions, control fluids, or provide a compliant contact around structured surfaces.
Preparation should account for the intended function, target thickness, curing conditions, and required surface treatment. Engineers also need to consider whether the layer must remain transparent, flexible, chemically stable, conformal, or electrically and environmentally isolating. Evaluating these requirements before fabrication helps align the layer's properties with the device architecture and reduces reliability problems during operation.
They are used in microfluidic devices, flexible sensors, soft actuators, and protective coatings. In microfluidics, the layer can support fluid control and sealing; in flexible systems, elasticity helps accommodate deformation. The same material can also provide optical transparency, electrical or environmental isolation, or a biocompatible interface, making it adaptable across several device designs.
Within microfluidic devices, the layer can help structure channels or interfaces and form conformal seals against the surrounding surfaces. Its flexibility supports contact with device features, while surface treatment can influence interactions at those interfaces. These characteristics make the material useful for controlling fluid regions and for rapidly prototyping devices whose geometry or sealing requirements may change.
Its elastic behavior allows the layer to accommodate deformation in flexible sensors and soft actuators rather than functioning as a rigid surface. Depending on the design, it can also contribute to protection or isolation from the environment. Engineers select thickness and curing conditions to match the required mechanical response and device reliability, while transparency may assist some device configurations.