Transcatheter Aortic Valve
Transcatheter Aortic Valve - Related Videos
07:46
Automatic Surgery in Transcatheter Aortic Valve Replacement Using Augmented Reality
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Cited by 2 •
2024
This article presents the design and implementation of an automatic surgery module based on augmented reality (AR)- based 3D reconstruction. The system enables remote surgery by allowing surgeons to inspect reconstructed features and replicate surgical hand movements as if they were performing the surgery in close proximity.
06:04
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Cited by 1 •
2025
An upper-extremity approach for secondary access during transfemoral transcatheter aortic valve implantation is associated with fewer secondary access site-related bleeding complications and reduces time to mobilization in patients requiring extended pacing. This protocol aims to provide an extensive overview of the upper-extremity approach and guide operators in adopting this methodology.
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
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Cited by 4 •
2017
Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.
08:55
Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification
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Cited by 16 •
2017
This protocol describes the isolation, culture, and calcification of rat-derived valve interstitial cells, a highly physiological in vitro model of calcific aortic valve disease (CAVD). Exploitation of this rat model facilitates CAVD research in exploring the cell and molecular mechanisms that underlie this complex pathological process.
04:51
Isolation of Mouse Valve Interstitial Cells: An Enzymatic Method to Isolate and Culture VICs from Mouse Aortic Valve
0 Views •
2025
In this video, we demonstrate the isolation of aortic valve interstitial cells from the heart of an adult mouse using a two-step collagenase procedure and their subsequent culture in low volume of growth media.
FAQs
The expandable frame provides radial force, pressing the prosthesis against the surrounding native valve region after deployment. This support helps maintain stability while the device regulates blood flow. Engineers must balance sufficient outward force for anchoring with a design that can still be compressed inside the delivery catheter and expanded accurately at the intended location.
Sealing helps limit unwanted blood flow around the implanted prosthesis, while fatigue resistance allows the device to tolerate repeated mechanical loading over time. These requirements work alongside biocompatible materials, which must function in contact with the body. Together, they influence whether the valve can maintain effective flow control and structural performance after implantation.
During deployment, the prosthesis displaces or anchors within the calcified native leaflets. This interaction helps secure the device in the diseased valve region while its functional components regulate one-way blood flow. The relationship between leaflet calcification, frame expansion, and positioning is therefore central to achieving stable placement and restoring more effective cardiac output.
The prosthesis is first compressed within a delivery catheter so it can be advanced through a blood vessel. The catheter carries the device to the heart, where the valve is expanded and deployed inside the native aortic valve. Successful delivery depends on preserving controlled movement, accurate positioning, and reliable expansion at the target site.
Development requires coordination among biocompatible materials, collapsibility, radial force, sealing, fatigue resistance, and precise positioning. Improving one feature may affect another: the device must be compact enough for catheter delivery yet strong enough to anchor and maintain function after expansion. These linked constraints make transcatheter valve design an integrated engineering problem rather than a single-material or single-component task.
Transcatheter aortic valves are primarily relevant for severe aortic stenosis, particularly when an alternative to open surgical repair is desirable. The approach expands less-invasive treatment options for patients with elevated surgical risk. By supporting one-way flow through the aortic position, the implanted prosthesis can improve cardiac output while avoiding the same form of open procedure.