J-shaped Cannula

A J-shaped cannula is a specialized curved tube used to establish controlled access to a vessel or anatomical compartment, enabling precise fluid delivery or sample collection in experimental research. Its curved tip follows the target anatomy and helps maintain a stable pathway for administering solutions, infectious inocula, treatments, or collecting biological fluids under defined conditions. In immunology and infection studies, this device supports reproducible animal procedures, standardized exposure protocols, and longitudinal sampling while limiting disruption during repeated access. These capabilities help researchers assess pathogen behavior, host immune responses, treatment effects, and disease progression with greater experimental control.

J-shaped Cannula - Related Videos

Research

JoVE EoE - Neurotherapeutics

Cannula Implantation into the Cisterna Magna in a Mouse Model

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2025

Source: Xavier, A. L. R., et al. Cannula Implantation into the Cisterna Magna of Rodents. J. Vis. Exp. (2018)This video demonstrates the procedure for implanting a cannula into the cisterna magna of an anesthetized mouse. The technique involves guiding a needle-mounted cannula through the dura into the inverted triangular cisterna magna and securing it for targeted delivery into the cerebrospinal fluid.

Education

JoVE Core - Medical-Surgical Nursing

Administering Oxygen by Nasal Cannula

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2025

Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations. Nasal Cannulas A nasal cannula is a lightweight tube split into two prongs placed in the nostrils, connected...

Morphometric Analyses of Shape: The Analysis Software Toolbox for Craniofacial Shape Quantification in Zebrafish

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2026

This work describes a protocol for quantifying craniofacial cartilage shape using free software (tpsDigs2, MorphoJ, and PAST) to measure changes in facial structure in zebrafish larvae.

Molecular Shape and Polarity

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2020

Dipole Moment of a Molecule Polar covalent bonds connect two atoms with differing electronegativities, leaving one atom with a partial positive charge (δ+) and the other atom with a partial negative charge (δ–), as the electrons are pulled toward the more electronegative atom. This separation of charge gives rise to a bond dipole moment. The magnitude of a bond dipole moment is represented by the Greek letter mu (µ) and is given by the formula shown here, where Q is the magnitude of the...

VSEPR Theory and the Basic Shapes

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2020

Overview of VSEPR Theory Valence shell electron-pair repulsion theory (VSEPR theory) enables us to predict the molecular structure, including approximate bond angles around a central atom, of a molecule from an examination of the number of bonds and lone electron pairs in its Lewis structure. The VSEPR model assumes that electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between these electron pairs by maximizing the distance between them.

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