Intravesical Pessary
Intravesical Pessary - Related Videos
08:43
An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
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Cited by 12 •
2012
Establishing an orthotopic bladder tumor model to evaluate antitumor effects of intravesically delivered saRNA and monitoring tumor growth by ultrasound and bioluminescent imaging.
04:28
Modeling Orthotopic Bladder Tumor in Mouse Model: A Procedure for Intravesical Administration of Cancer Cells into Murine Bladder
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2023
In this video, we describe the intravesical procedure of delivering cancer cells into the bladder of a mouse model. This procedure helps generate an orthotopic bladder tumor model that can be used to develop therapeutic strategies.
08:08
The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
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Cited by 42 •
2012
Cystometry is an efficient technique to measure bladder function of small animals in vivo. The bladder is continuously infused at rates controlled through an intravesical catheter, whereas the urethra is left free for micturition. This allows for repetitive filling and emptying of the bladder, while intravesical pressure and voided volume are recorded.
06:23
A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
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Cited by 8 •
2017
This protocol describes the generation of murine orthotopic bladder tumors in female C57BL/6J mice and the monitoring of tumor growth.
09:31
Evaluating the Procedure for Performing Awake Cystometry in a Mouse Model
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Cited by 10 •
2017
This study describes the surgical procedures and experimental techniques for performing awake cystometry in a freely moving mouse. In addition, it provides experimental evidence to support its optimization and standardization.
FAQs
Mechanical action is determined by where the device contacts the bladder neck, urethral opening, or nearby tissues. That contact can change the physical support around the bladder outlet and influence how urine passes or how continence is maintained. Consequently, the same general device concept may produce different effects when its design or position changes the tissues it engages.
The main distinction is the anatomical site through which mechanical influence is applied. A vaginal pessary represents the more familiar pelvic-support approach, whereas an intravesical pessary uses a specialized urological position to affect the bladder outlet or nearby structures. This difference makes device placement, retention, and contact relationships central to interpreting its intended function.
Design and retention determine whether the device remains positioned to maintain the intended contact with the bladder neck, urethral opening, or surrounding tissues. If that relationship changes, its influence on urine flow, continence, or pelvic support may also change. Evaluation therefore considers not only the device’s presence, but also how securely and appropriately it remains positioned.
Placement typically occurs through the urethra, allowing the device to reach the urinary bladder and assume its intended position. A meaningful procedural assessment must then consider the device’s location, retention, and contact with relevant outlet tissues. These factors connect the physical placement step with the functional effects being evaluated in lower urinary tract care.
Assessment can focus on changes in urine flow, continence, and pelvic support, because these outcomes relate to the device’s mechanical interaction with the bladder outlet and surrounding tissues. The findings help show whether the selected position and design produce the intended influence. They also provide a basis for considering retention and potential complications during device evaluation.
This approach is relevant when examining urinary dysfunction, mechanical device-based treatment, and lower urinary tract care. It also provides context for comparing historical and contemporary strategies that use physical support or altered outlet mechanics. Because the method is a specialized urological application rather than a routine vaginal-pessary approach, its evaluation centers on bladder and urethral relationships.