Non-pharmacologic Pain Therapy

Non-pharmacologic pain therapy comprises treatments that reduce pain without relying on medications, making it an important component of comprehensive medical care. These approaches act through different mechanisms, including altering nociceptive signaling, improving movement and muscle function, reducing stress-related amplification, and changing attention or cognitive responses to pain. Common options include physical therapy, exercise, heat or cold, transcutaneous electrical nerve stimulation, cognitive behavioral therapy, relaxation training, and mindfulness practices. Used alone or alongside medication, they can improve function, support self-management, reduce treatment-related risks, and provide adaptable strategies for acute, chronic, and procedure-related pain.

Non-pharmacologic Pain Therapy - Related Videos

Research

JoVE Journal - Behavior

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

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Cited by 24 •

2016

The goal of this procedure is to demonstrate a battery of quantitative techniques for sensory and pain measurement in humans. The equipment and techniques described are commonly found in pain clinics or are easy to obtain.

Chuzhen Therapy as a Non-Invasive Traditional Chinese Therapy for Neck Pain

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2025

Chuzhen therapy has effectively addressed various conditions, with success in alleviating neck pain and enhancing patients' quality of life. This article presents Chuzhen as a safe and efficacious traditional Chinese method tailored specifically for the treatment of neck pain.

Research

JoVE Journal - Medicine
Free Sample

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse

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Cited by 181 •

2016

Osteoarthritis (OA), or degenerative joint disease, is a debilitating condition associated with pain that remains only partially controlled by available analgesics. Animal models are being developed to improve our understanding of OA-related pain mechanisms. Here we describe the methodology for the monoiodoacetate model of OA pain in the mouse.

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies

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Cited by 8 •

2022

Partial sciatic nerve ligation induces long-lasting chronic neuropathic pain, characterized by exaggerated responses to thermal and mechanical stimuli. This mouse model of neuropathic pain is commonly used to study innovative therapies for pain management. This article describes in detail the surgical procedure to improve standardization and reproducibility.

Research

JoVE Journal - Behavior
Free Sample

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

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Cited by 17 •

2016

Human pain models are valuable tools used to assess the analgesic potential of novel compounds and predict their clinical efficacy, especially when used in an integrated manner. Although implementation of these models is complex, with proper execution, the pain models described in this protocol can provide predictive and reliable results.

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