Lumbar Disc Degeneration

Lumbar disc degeneration is the progressive structural and biochemical deterioration of intervertebral discs in the lower spine, a common condition that can contribute to low back pain, stiffness, and nerve-related symptoms. With aging, mechanical stress, and other risk factors, disc cells and extracellular matrix lose proteoglycans and water, reducing disc height and load distribution; fissures in the annulus fibrosus may allow the nucleus pulposus to deform or irritate nearby tissues. In medicine, understanding this process supports clinical assessment, magnetic resonance imaging, physical rehabilitation, pain management, and, when necessary, surgical planning, while ongoing research seeks treatments that preserve or restore disc function.

Lumbar Disc Degeneration - Related Videos

Research

JoVE Journal - Medicine

Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury

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Cited by 18 •

2017

Intervertebral disc degeneration is a significant contributor to back pain and a leading cause of disability worldwide. Numerous animal models of intervertebral disc degeneration exist. We demonstrate an ovine model of intervertebral disc degeneration, utilizing a drill bit, which achieves a consistent disc injury and reproducible level of disc degeneration.

Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation

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2025

Source: Wang, L., et.al. Full-Endoscopic Isolation Zone Technique for the Treatment of Lumbar Disc Herniation. J. Vis. Exp.(2023)This video demonstrates a minimally invasive endoscopic procedure to treat lumbar disc herniation by removing the protruded nucleus pulposus and ruptured annulus fibrosus. The technique decompresses the affected nerve root, alleviates pain, and restores nerve function through targeted tissue resection and radiofrequency modulation.

Operational and Intervention Effects of Targeted Tuina in Lumbar Intervertebral Disc Degeneration Model Rabbits

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Cited by 1 •

2023

The finger tactile measurement system quantifies tactile pressure on the finger using a highly sensitive electrosurgical pressure sensor, with software displaying and accurately recording the pressure data and video in real time. Two analysis modules unify the data processing for thumb tracking and conditioning during Tuina.

Intrathecal Placement of Lumbar Drain: A Technique to Withdraw Cerebrospinal Fluid from the Lumbar Spine in Porcine Model

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2025

This video describes the technique of intrathecal placement of a lumbar drain in a porcine ischemic model, which helps in draining the cerebrospinal fluid to a drainage system. The cerebrospinal fluid pressure is monitored by the drainage system, and fluid is drained to maintain a constant cerebrospinal fluid pressure.

Surgical Induction of Lumbar Spine Instability in Mouse Model: A Surgical Procedure for the Resection of the Lumbar Spinous Processes and Connected Ligaments in Murine Model

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2025

In this video, we describe the surgical procedure to induce lumbar spine instability in a mouse model by resecting the Lumbar L3 to L5 spinous process along with supraspinous and interspinous ligaments.

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