Posterior Circulation Stroke

Posterior circulation stroke is an ischemic or hemorrhagic injury affecting brain regions supplied by the vertebral and basilar arteries, including the brainstem, cerebellum, and occipital lobes. Ischemic events typically occur when a thrombus or embolus blocks blood flow, depriving tissue of oxygen, while vessel rupture causes bleeding and pressure-related damage. Symptoms may include vertigo, imbalance, double vision, weakness, altered sensation, impaired coordination, or reduced consciousness, making recognition challenging because they can resemble benign vestibular disorders. Prompt neurological assessment and vascular imaging support diagnosis, while timely reperfusion or hemorrhage management can limit disability and improve outcomes.

Posterior Circulation Stroke - Related Videos

Research

JoVE Journal - Medicine

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

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Cited by 2 •

2015

Minimally invasive thumb-sized pterional craniotomy for aneurysm clipping has afforded our patients with a shorter hospital stay at a lower cost compared to the national average.

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy

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Cited by 3 •

2015

The goal of this protocol is to photochemically induce ischemic injury to the posterior optic nerve in rat. This model is critical to studies of the pathophysiology of posterior ischemic optic neuropathy, and therapeutic approaches for this and other optic neuropathies, as well as of other CNS ischemic diseases.

Research

JoVE Journal - Medicine
Free Sample

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

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Cited by 103 •

2014

Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.

Isolating Short Posterior Ciliary Arteries: A Protocol to Excise Intact Short Posterior Ciliary Microvessels from Porcine Eye

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2025

This video describes the protocol to isolate the short posterior ciliary arteries from the porcine eye. The isolated short posterior arteries are a suitable source for elucidating the molecular insights and protein profiles of the ocular blood vessels.

Isolation of Circulating Tumor Cells in an Orthotopic Mouse Model of Colorectal Cancer

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Cited by 13 •

2017

We describe the establishment of orthotopic colorectal tumors via injection of tumor cells or organoids into the cecum of mice and the subsequent isolation of circulating tumor cells (CTCs) from this model.

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