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JoVE Journal
Medicine

This content is Open Access.

Modeling Stroke in Mice
 

Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

Article doi: 10.3791/51729
July 31st, 2014

Summary July 31st, 2014

Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.

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