Stroke Spasticity

Stroke spasticity is a movement disorder that can develop after a stroke, causing involuntary muscle stiffness, increased muscle tone, and restricted joint movement. Damage to descending motor pathways reduces normal inhibition of spinal reflexes, making muscle responses abnormally strong and often more pronounced when a limb is moved quickly. In medicine, clinicians assess spasticity through muscle tone, resistance to passive movement, posture, and functional limitations. These findings guide rehabilitation strategies, including stretching, positioning, task-based therapy, and selected treatments such as botulinum toxin or oral medications, with the aim of improving mobility, comfort, independence, and quality of life.

Stroke Spasticity - Related Videos

Research

JoVE Journal - Medicine
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Breathing-controlled Electrical Stimulation (BreEStim) for Management of Neuropathic Pain and Spasticity

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Cited by 9 •

2013

The purpose is to present a new method, breathing-control electrical stimulation (BreEStim) for management of neuropathic pain and spasticity.

Research

JoVE Journal - Bioengineering

Isokinetic Robotic Device to Improve Test-Retest and Inter-Rater Reliability for Stretch Reflex Measurements in Stroke Patients with Spasticity

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Cited by 4 •

2019

Using a robotic isokinetic device with electromyography (EMG) measurements, this protocol illustrates that isokinetic motion itself can improve inter-rater reliability for the angle of catch measurements in stroke patients with mild elbow flexor spasticity.

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

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Cited by 101 •

2018

Here, we present a protocol to develop and apply a mobile game-based virtual reality program for the recovery of upper limb dysfunction in patients with stroke. The present study shows that the mobile program is feasible and effectively promotes upper limb recovery in stroke patients.

Research

JoVE Journal - Medicine
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Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

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Cited by 104 •

2014

Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.

Research

JoVE Journal - Neuroscience
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The Stroke Preclinical Assessment Network Multi-Laboratory Model of Thromboembolic Stroke with Thrombolysis: TE-MCAo

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2025

To simulate thromboembolic stroke, emboli prepared from heterologous rat blood were injected into the middle cerebral artery, followed by administration of systemic thrombolysis for recanalization. This version of the model is optimized for use in a multi-laboratory network and supports testing multiple candidate therapeutics.

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