Gastric Lavage Technique

Gastric lavage is a clinical decontamination technique that removes stomach contents through a tube, historically used after certain poisonings or drug overdoses. After airway protection and placement of a large-bore orogastric tube, repeated instillation and aspiration of small volumes of fluid mechanically evacuate material from the stomach. Because the procedure can cause aspiration, esophageal injury, fluid disturbances, and other complications, clinicians reserve it for carefully selected, potentially life-threatening ingestions when treatment can begin soon after exposure. In pharmacology, gastric lavage illustrates how drug absorption, toxicokinetics, timing, and risk-benefit assessment guide emergency management.

Gastric Lavage Technique - Related Videos

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JoVE Journal - Medicine
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Enhanced Spatial Mapping of Mouse Gastric Muscle Layers Using a Modified Swiss Roll Technique

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2025

This protocol outlines a whole-stomach immunostaining method modified from the "Swiss roll" technique originally developed for the murine intestine.

Research

JoVE EoE - Gastrointestinal Cancer

Peritoneal Low-density Neutrophil Isolation: A Technique to Obtain Low-density Neutrophils from Peritoneal Lavage Fluid Using Magnetic Activated Cell Sorting

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2023

In this video, we describe the procedure for isolating low-density neutrophils, or LDNs, from the peritoneal lavage fluid of a postoperative human patient. The LDNs thus obtained can be used in further downstream experiments to understand their role in tumor growth and progression.

Research

JoVE Journal - Medicine
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Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield

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Cited by 47 •

2014

We describe a research technique for fiberoptic bronchoscopy and bronchoalveolar lavage using low pressure suction. The technique is used to harvest immune cells from the lung bronchoalveolar surfaces. Local anesthetic and mild conscious sedation (midazolam) is used. Subjects tolerate the procedure well and experience minimal side effects.

Bronchoalveolar Lavage of Murine Lungs to Analyze Inflammatory Cell Infiltration

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Cited by 155 •

2017

The health status of the lung is reflected by the type and number of immune cells that are present in the bronchioles of the lung. We describe a bronchoalveolar lavage technique that allows the isolation and study of nonadherent cells and soluble factors from the lower respiratory tract of mice.

Roux-en-Y Gastric Bypass Operation in Rats

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Cited by 45 •

2012

Numerous studies using gastric bypass rat models have been recently conducted to uncover the underlying physiological mechanisms of Roux-en-Y gastric bypass operations. This article aims to demonstrate and discuss the technical and experimental details of our published gastric bypass rat model to understand advantages and limitations of this experimental tool.

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