Negative State Relief Model

The Negative State Relief Model is a psychological theory proposing that people may help others partly to reduce their own unpleasant emotional states. When sadness, guilt, or distress heightens, helping behavior can provide a route to improved mood through the rewarding consequences of assistance or by shifting attention away from personal discomfort. The model helps explain why prosocial actions can occur without purely altruistic motives and guides research on mood, helping, empathy, and situational factors that influence cooperation. Its significance extends to social behavior studies and interventions, while experiments test when helping reflects genuine concern, self-focused relief, or both.

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Research

JoVE Journal - Immunology and Infection

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

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Cited by 5 •

2020

Infection of neonatal mice with bioluminescent E. coli O1:K1:H7 results in a septic infection with significant pulmonary inflammation and lung pathology. Here, we describe procedures to model and further study neonatal sepsis using longitudinal intravital imaging in parallel with enumeration of systemic bacterial burdens, inflammatory profiling, and lung histopathology.

Education

JoVE Core - Biology

Negative Regulator Molecules

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2019

Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a cell’s progression through the cell cycle—or pause it—until the cell meets specific criteria. Three of the best-understood negative regulators are p53, p21, and retinoblastoma protein (Rb). The regulatory roles of each of these proteins were discovered after faulty copies were found in cells with uncontrolled replication (i.e., cancer). These...

Utilization of Capsules for Negative Staining of Viral Samples within Biocontainment

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Cited by 3 •

2017

This protocol provides instruction for negative staining virus samples which can easily be used in BSL-2, -3, or -4 laboratories. It includes the use of an innovative processing capsule, which protects the transmission electron microscopy grid and provides the user easier handling in the more turbulent environments within biocontainment.

Negative Externalities

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2025

A negative externality occurs when an economic transaction imposes unintended costs on third parties who are not directly involved in the market transaction. These external costs are not captured in the market price. Negative Externalities and Market Failure Consider a chemical manufacturing plant that produces industrial chemicals for sale. The plant's private costs include raw materials, labor, equipment, and maintenance, which are reflected in the market price of the chemicals. However,...

Positive, Negative, and Zero Work

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2025

Work is done on an object when energy is transferred to the object. In other words, work is done when a force acts on a body that undergoes a displacement from one position to another. By definition, the work done by a force is the integral of the force with respect to the displacement along its path. Forces can vary as a function of position, and displacements can occur along various paths between two points. The magnitude of a force multiplied by the cosine of the angle that the force makes...

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