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Immunology and Infection

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Underlätta Drug Discovery
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Underlätta Drug Discovery: En automatiserad hög halt Inflammation analys i zebrafisk

Article DOI: 10.3791/4203-v • 07:50 min • July 16th, 2012
July 16th, 2012 •
1, 2, 1, 2, 1,2, 1
1Institute for Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany, 2Institute for Applied Informatics, Karlsruhe Institute of Technology, Karlsruhe, Germany

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Här beskriver vi ett nytt high-halt kemiskt inducerad inflammation analys som syftar till att identifiera immun-modulerande bioaktiva substanser. Vi har framgångsrikt kombinerat automatiserad mikroskopering med egna utvecklade program skript som gör det möjligt automatisk kvantifiering av det inflammatoriska svaret samt ytterligare databehandling, analys, gruvdrift och lagring.

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Immunologi 65 Genetics zebrafisk Inflammation läkemedelsutveckling HCS High Content Screening automatiserad mikroskopering
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