Name: 2013年3月：这个月在朱庇特 (视频) | JoVE Journal
Uploaded: 2013-03-01T16:00:00.000+00:00
Duration: 3 min 3 s
Description: 了解JoVE期刊2013年3月号中神经科学与生物学领域的前沿研究方法。通过可视化实验技术深入探索复杂生物机制，促进科研可重复性与知识共享。

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5 minutes

<h2 class="jove_title"><a href="https://www.jove.com/video/4326">小鼠淋巴管系统的无创光学成像</a></h2>
Holly A. Robinson， SunKuk Kwon， Mary A. Hall， John C. Rasmussen， Melissa B. Aldrich， 德克萨斯大学休斯顿健康科学中心-Eva M. Sevick-Muraca 分子影像中心 （CMI）
最近开发的使用近红外荧光 （NIRF） 的成像技术可能有助于阐明淋巴系统在癌症转移、免疫反应、伤口修复和其他淋巴相关疾病中的作用。
<h2 class="jove_title"><a href="https://www.jove.com/video/4379">婴儿脑代谢和血流动力学的无创光学测量</a></h2>
林培义1， Nadege Roche-Labarbe1， 2， Mathieu Dehaes3， Stefan Carp1， Angela Fenoglio3， Beniamino Barbieri4， Katherine Hagan1，P. Ellen Grant3， Maria Angela Franceschini1 1Athinoula A. Martinos 哈佛医学院马萨诸塞州总医院生物医学成像中心， 2Lab. PALM， Université de Caen Basse-Normandie， 3胎儿-新生儿神经影像学和发育科学中心，波士顿儿童医院，哈佛医学院，4ISS， INC.
我们将脑血红蛋白氧合的频域近红外光谱测量与脑血流指数的弥散相关光谱测量相结合，以估计氧代谢指数。我们测试了该措施作为床边筛查工具的效用，以评估新生儿大脑的健康和发育。
<h2 class="jove_title"><a href="https://www.jove.com/video/50096">使用 Algisyl-LVR 降低衰竭心脏的左心室壁应力和改善功能</a></h2>
Lik Chuan Lee1， 张志宏1， Andrew Hinson2， Julius M. Guccione1 1外科部，UCSF/VA医疗中心，2临床与监管部门，LoneStar Heart， Inc.
本文介绍了在衰竭心脏中植入新型水凝胶并量化其对左心室壁应力和功能影响的程序。这些程序已成功应用于狗和人类。
<h2 class="jove_title"><a href="https://www.jove.com/video/50272">开发基于音频的虚拟游戏环境，以协助盲人学习导航技能</a></h2>
Erin C. Connors1， Lindsay A. Yazzolino1， Jaime Sánchez2， Lotfi B. Merabet1 1哈佛医学院马萨诸塞州眼耳医院眼科眼科视觉神经可塑性实验室，2智利大学计算机科学系和高级教育研究中心 （CARE）

<h2 class="jove_title"><a href="https://www.jove.com/video/4325">通过多相机光场成像确定三维流场</a></h2>
Tadd T. Truscott1， Jesse Belden2， Joseph R. Nielson1， David J. Daily1， Scott L. Thomson1 1杨百翰大学机械工程系， 2 Naval Undersea Warfare Center， Newport， RI
介绍了一种对一系列流体流进行定量三维 （3D） 成像的技术。使用光场成像领域的概念，我们从图像阵列中重建 3D 体积。我们的 3D 结果涵盖广泛的范围，包括速度场和多相气泡尺寸分布。

No conflicts of interest declared.

march 2013: this month in jove

March 2013: This Month in JoVE

Here are some highlights from the March 2013 issue of Journal of Visualized Experiments (JoVE).
This month, JoVE features several video articles in the Clinical and Translational Medicine section. In the ophthalmology department, Connors et al. of Massachusetts Eye &amp; Ear and Harvard Medical School have developed an audio-based virtual environment simulator to help blind people improve their navigation skills. The simulator allows users to build cognitive maps of three-dimensional spaces in the context of a video game-using only audio cues. The users were not aware that the virtual building in the game represents an actual building; furthermore, the users were never asked to recall the building layout while playing. Nonetheless it appears that the game can help them navigate through unfamiliar spaces.
At Massachusetts General Hospital and Harvard Medical School, Lin et al. are developing an improved method to noninvasively measure brain metabolism and blood flow in newborns. This method combines measurements of hemoglobin oxygen saturation (SO2) with cerebral blood flow index (CBFi), which provides accurate measurements of cerebral metabolism and hemodynamics. This method also complies with neonatal ICU policies, making it potentially useful for assessing brain health, development, and response to therapy in newborns.
Also in this section, Lee et al. of UC San Francisco/VA Medical Center demonstrate how a biopolymer gel, derived from polysaccharides found in brown algae, can help patients with heart failure. The alginate-based biopolymer is injected into the area between the base and apex of the left ventricle free wall. This reduces left ventricle size and thickens its free wall; it also reduces left ventricular wall stress, as assessed by mathematical modeling. This therapy, called Algisyl-LVR, is currently in clinical development for treating patients with dilated cardiomyopathy.
In JoVE Immunology and Infection, Robinson et al. of University of Texas Health Science Center-Houston demonstrate a noninvasive technique for imaging lymphatic vessels, which are involved in many physiological and disease processes. A near-infrared fluorescent dye, such as indocyanine green (ICG), is injected intradermally-allowing the lymphatic vasculature to be visualized using a near-infrared fluorescence imaging system.
The JoVE Applied Physics section features a method in the field of fluid mechanics, developed at Brigham Young University in collaboration with the Naval Undersea Warfare Center of Newport, Rhode Island. Truscott et al. describe a novel technique for quantitative three-dimensional imaging of fluid flow fields, such as the airflow passing over a set of synthetic vocal folds, or bubbly flow fields. This method can help resolve a range of problems in the area of fluid mechanics.
This summary provides a preview of the cutting-edge video publications appearing this month in JoVE. Visit the website and check out the full-length articles, plus many more, in JoVE: The Journal of Visualized Experiments.

Here are some highlights from the March 2013 issue of Journal of Visualized Experiments (JoVE).

Here are some highlights from the March 2013 issue of Journal of Visualized Experiments (JoVE).
This month, JoVE features several video articles in the ...

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2013年3月：这个月在朱庇特

了解JoVE期刊2013年3月号中神经科学与生物学领域的前沿研究方法。通过可视化实验技术深入探索复杂生物机制，促进科研可重复性与知识共享。

2013年3月：这个月在朱庇特 (视频) | JoVE Journal

Wendy Chao

Aaron Kolski-Andreaco

March 2013: This Month in JoVE

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