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Chapters
- 00:05Title
- 01:15Scaffold Fabrication
- 02:58Bioreactor Assembly
- 05:34Bioreactor Characterization
- 07:00Vibratory Cell Culture
- 08:44Results: Vibration Induces Extra Cellular Matrix (ECM) Protein Expression in MSC Cultures
- 10:44Conclusion
A novel vocal fold bioreactor capable of delivering physiologically relevant, vibratory stimulation to cultured cells is constructed and characterized. This dynamic culture device, when combined with a fibrous poly(ε-caprolactone) scaffold, creates a vocal fold-mimetic environment that modulates the behaviors of mesenchymal stem cells.
