Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Alice Sosic; Marta Cappellini; Matteo Scalabrin; Barbara Gatto

doi:10.3791/52474

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免疫与感染

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核衣壳退火介导电泳（NAME）分析允许HIV-1核衣壳抑制剂的快速鉴定

Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

JoVE 杂志
免疫与感染

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JoVE 杂志免疫与感染

Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

核衣壳退火介导电泳（NAME）分析允许HIV-1核衣壳抑制剂的快速鉴定

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8,859 Views

•

08:33 min

•

January 19, 2015

DOI:

10.3791/52474-v

DOI:

10.3791/52474-v

•

08:33 min

January 19, 2015

•

2 Views

Alice Sosic¹, Marta Cappellini¹, Matteo Scalabrin², Barbara Gatto¹

¹Department of Pharmaceutical and Pharmacological Sciences,University of Padova, ²The RNA Institute,SUNY Albany

Summary

This protocol describes NAME, an assay that allows the rapid identification of molecules able to inhibit in vitro the chaperone activities of HIV-1 nucleocapsid protein.

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核衣壳退火介导电泳（NAME）分析允许HIV-1核衣壳抑制剂的快速鉴定

Summary

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